CAS 2292-16-2

(-)-Neferina

Descripción:

(-)-Neferina es un alcaloide que se encuentra de forma natural, extraído principalmente de las semillas de la planta de loto, en particular de la especie *Nelumbo nucifera*. Se caracteriza por su estructura quiral, que contribuye a su actividad biológica. El compuesto exhibe una variedad de propiedades farmacológicas, incluyendo efectos antiinflamatorios, antioxidantes y potencialmente neuroprotectores. (-)-Neferina ha despertado interés en la química medicinal debido a su capacidad para modular diversas vías biológicas, lo que lo convierte en un candidato para investigaciones adicionales en aplicaciones terapéuticas. La sustancia se estudia típicamente en el contexto de la medicina tradicional y la farmacología moderna, con investigaciones en curso sobre sus mecanismos de acción y eficacia. Su solubilidad y estabilidad pueden variar dependiendo del disolvente y las condiciones, lo cual es crucial para su aplicación en estudios biológicos. En general, (-)-Neferina representa un compuesto significativo en el campo de los productos naturales y la farmacognosia, destacando la importancia de las sustancias derivadas de plantas en el descubrimiento de fármacos.

Fórmula: C₃₈H₄₄N₂O₆

InChI: InChI=1/C38H44N2O6/c1-39-15-14-27-21-36(44-5)38(23-30(27)31(39)17-24-7-10-28(42-3)11-8-24)46-34-19-25(9-12-33(34)41)18-32-29-22-37(45-6)35(43-4)20-26(29)13-16-40(32)2/h7-12,19-23,31-32,41H,13-18H2,1-6H3/t31-,32-/m1/s1

Clave InChI: InChIKey=MIBATSHDJRIUJK-ZWXJPIIXSA-N

SMILES: C([C@@H]1C=2C(=CC(OC)=C(OC3=CC(C[C@H]4C=5C(=CC(OC)=C(OC)C5)CCN4C)=CC=C3O)C2)CCN1C)C6=CC=C(OC)C=C6

Sinónimos:

• 4-[[(1R)-6,7-Dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-1-yl]methyl]-2-[[(1R)-6-methoxy-1-[(4-methoxyphenyl)methyl]-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl]oxy]phenol
• 4-[[(1S)-1,2,3,4-Tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]-2-[[(1R)-1,2,3,4-tetrahydro-6-methoxy-1-[(4-methoxyphenyl)methyl]-2-methyl-7-isoquinolinyl]oxy]phenol
• 4-{[(1R)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl}-2-{[(1R)-6-methoxy-1-(4-methoxybenzyl)-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl]oxy}phenol
• 4′′-O-Methylliensinine
• Methylliensinine
• Neferin
• Phenol, 4-[[(1S)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]-2-[[(1R)-1,2,3,4-tetrahydro-6-methoxy-1-[(4-methoxyphenyl)methyl]-2-methyl-7-isoquinolinyl]oxy]-
• Neferine
• 4-[[(1R)-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-1-yl]methyl]-2-[[(1R)-6-methoxy-1-(4-methoxybenzyl)-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl]oxy]phenol
• Neferine USP/EP/BP
• 4-[(1,2,3,4-Tetrahydro-6,7-dimethoxy-2-methylisoquinolin-1-yl)methyl]-2-[[1,2,3,4-tetrahydro-6-methoxy-1-[(4-methoxyphenyl)methyl]-2-methylisoquinolin-7-yl]oxy]phenol

Phenol, 4-[[(1S)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]-2-[[(1R)-1,2,3,4-tetrahydro-6-methoxy-1-[(4-methoxyphenyl)methyl]-2-methyl-7-isoquinolinyl]oxy]-

CAS: 2292-16-2

Fórmula: C₃₈H₄₄N₂O₆

Pureza: 99%

Forma y color: Solid

Peso molecular: 624.7658

Ref: IN-DA002LIY

Neferine

CAS: 2292-16-2

Fórmula: C₃₈H₄₄N₂O₆

Peso molecular: 624.78

Ref: 7W-GY2445

Neferine

CAS: 2292-16-2

Neferine

Pureza: ≥98%

Peso molecular: 624.77g/mol

Ref: 54-BUP06165

4-(((S)-6,7-Dimethoxy-2-Methyl-1,2,3,4-Tetrahydroisoquinolin-1-Yl)Methyl)-2-(((R)-6-Methoxy-1-(4-Methoxybenzyl)-2-Methyl-1,2,3,4-Tetrahydroisoquinolin-7-Yl)Oxy)Phenol

CAS: 2292-16-2

4-(((S)-6,7-Dimethoxy-2-Methyl-1,2,3,4-Tetrahydroisoquinolin-1-Yl)Methyl)-2-(((R)-6-Methoxy-1-(4-Methoxybenzyl)-2-Methyl-1,2,3,4-Tetrahydroisoquinolin-7-Yl)Oxy)Phenol

Pureza: 98%

Peso molecular: 624.77g/mol

Ref: 54-OR1023075

Neferine

CAS: 2292-16-2

Neferine

Fórmula: C₃₈H₄₄N₂O₆

Pureza: 95%~99%

Peso molecular: 624.778

Ref: BP-BP0987

Neferine

CAS: 2292-16-2

Neferine: anti-tumor, enhances DOX efficacy, prevents diabetic vasculopathy; mediates via CYP3A4, GSH depletion, blocks ROS/Akt/NF-κB.

Fórmula: C₃₈H₄₄N₂O₆

Pureza: 98.81% - 99.65%

Forma y color: Solid

Peso molecular: 624.77

Ref: TM-T5S1097

Neferine

CAS: 2292-16-2

Fórmula: C₃₈H₄₄N₂O₆

Peso molecular: 624.78

Ref: 4Z-N-107001

Neferine

CAS: 2292-16-2

Neferine is an alkaloid, which is derived from the seeds of Nelumbo nucifera, commonly known as the lotus plant. This compound acts as a bioactive molecule with diverse pharmacological properties, primarily through its antioxidant and neuroprotective modes of action. Neferine functions by scavenging reactive oxygen species and inhibiting oxidative stress pathways, making it significant in cellular protection. Furthermore, it modulates various signaling pathways that are crucial for maintaining cellular homeostasis and survival.

Fórmula: C₃₈H₄₄N₂O₆

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 624.77 g/mol

Ref: 3D-FN65588