CAS 23025-68-5

acetato de fragmento 3-8 de angiotensina ii, *humano

Descripción:

El fragmento 3-8 de angiotensina II, también conocido por su número CAS 23025-68-5, es un péptido que desempeña un papel significativo en el sistema renina-angiotensina, que regula la presión arterial y el equilibrio de fluidos. Este fragmento específico consiste en una secuencia de aminoácidos derivados de la molécula más grande de angiotensina II, abarcando específicamente los aminoácidos de las posiciones 3 a 8. Se caracteriza por su capacidad para unirse a los receptores de angiotensina, influyendo en la vasoconstricción y la secreción de aldosterona, afectando así la función cardiovascular. La forma de acetato indica que el péptido está acetilado, lo que puede mejorar su estabilidad y solubilidad en sistemas biológicos. Típicamente, los fragmentos de angiotensina II se estudian por sus efectos fisiológicos, incluyendo su papel en la hipertensión y la insuficiencia cardíaca. En entornos de laboratorio, este péptido se utiliza a menudo en investigaciones para explorar su actividad biológica y posibles aplicaciones terapéuticas. Al igual que con muchos péptidos, es importante manejarlo bajo condiciones apropiadas para mantener su integridad y actividad biológica.

Fórmula: C₄₀H₅₄N₈O₈

InChI: InChI=1/C40H54N8O8/c1-5-24(4)34(47-35(50)29(44-37(52)33(41)23(2)3)18-26-13-15-28(49)16-14-26)38(53)45-30(20-27-21-42-22-43-27)39(54)48-17-9-12-32(48)36(51)46-31(40(55)56)19-25-10-7-6-8-11-25/h6-8,10-11,13-16,21-24,29-34,49H,5,9,12,17-20,41H2,1-4H3,(H,42,43)(H,44,52)(H,45,53)(H,46,51)(H,47,50)(H,55,56)/t24-,29-,30-,31-,32-,33-,34-/m0/s1

SMILES: CC[C@H](C)[C@@H](C(=N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=N[C@@H](Cc1ccccc1)C(=O)O)O)O)N=C([C@H](Cc1ccc(cc1)O)N=C([C@H](C(C)C)N)O)O

Sinónimos:

• Angiotensin I/II (3-8)
• H-Val-Tyr-Ile-His-Pro-Phe-OH
• L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanine

Angiotensin II (3-8), Human

CAS: 23025-68-5

For cellular and molecular biology applications

Forma y color: Lyophilized powder, White

Ref: 02-J66457

Angiotensin I/II (3-8)

CAS: 23025-68-5

Ang IV, one of the major metabolites of angiotensin II, binds with high affinity to a new angiotensin binding site distinct and separate from angiotensin II receptors.

Fórmula: C₄₀H₅₄N₈O₈

Pureza: 99.1%

Forma y color: White Powder

Peso molecular: 774.92

Ref: 01-4018068

Angiotensin IV acetate

CAS: 23025-68-5

Angiotensin IV (Human) is a peptide hormone and peptidase inhibitor that belongs to the family of angiotensins. It is produced by the renin-angiotensin system and inhibits the action of angiotensin converting enzyme, an enzyme that converts angiotensin I into angiotensin II. Angiotensin IV has been used for research purposes as well as for therapeutic applications in cardiovascular diseases, hypertension, and congestive heart failure. Angiotensin IV is a high purity product with a purity greater than 99%.

Fórmula: C₄₀H₅₄N₈O₈

Pureza: Min. 95%

Peso molecular: 774.91 g/mol

Ref: 3D-PAN-4331-V

Angiotensin IV acetate

CAS: 23025-68-5

Angiotensin IV (human) is an active analogue of the chemoattractant protein, angiotensin. It is a potent anti-inflammatory cytokine that inhibits the production of pro-inflammatory cytokines, such as IL-10. Angiotensin IV (human) has been shown to significantly reduce the production of pro-inflammatory cytokines in mice with chronic inflammation and can be used to treat autoimmune diseases. The biological properties of this protein have been studied using polymerase chain reactions and cytosolic calcium assays. It has been shown to inhibit binding to both the angiotensin receptor and angiotensin converting enzyme. Angiotensin IV (human) also has locomotor activity.

Fórmula: C₄₀H₅₄N₈O₈

Pureza: Min. 95%

Peso molecular: 774.91 g/mol

Ref: 3D-PAN-4331

Angiotensin II (3-8), human

CAS: 23025-68-5

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Fórmula: C₄₀H₅₄N₈O₈

Peso molecular: 774.9 g/mol

Ref: 3D-PP50266

Angiotensin I/II (3-8)

CAS: 23025-68-5

Angiotensin I/II (3-8) H-Val-Tyr-Ile-His-Pro-Phe-OH is a peptide that has physiological effects and is used as a drug. It is an active analogue of the peptide hormone angiotensin II, which regulates blood pressure and fluid volume. Angiotensin I/II (3-8) H-Val-Tyr-Ile-His-Pro-Phe-OH binds to angiotensin receptors and stimulates the release of calcium ions from cytosolic stores in cells, leading to increased muscle contractions and vasoconstriction. This drug may also have effects on dopamine levels in the brain, locomotor activity, and biochemical properties such as enzyme activity or protein binding.br>
Angiotensin I/II (3-8) H-Val-Tyr-Ile-His Pro Phe OH has been shown to reduce the level of dopamine

Fórmula: C₄₀H₅₄N₈O₈

Pureza: Min. 95%

Peso molecular: 774.91 g/mol

Ref: 3D-FA110283