CAS 23327-57-3
:(±)-Clorhidrato de nefopam
Descripción:
(±)-Clorhidrato de nefopam es un compuesto sintético reconocido principalmente por sus propiedades analgésicas. Se clasifica como un analgésico no opioide y se utiliza a menudo para manejar el dolor, particularmente en casos donde los opioides tradicionales pueden no ser adecuados. La sustancia exhibe un mecanismo de acción único, principalmente a través de la inhibición de la recaptación de neurotransmisores como la serotonina, la norepinefrina y la dopamina, lo que contribuye a sus efectos analgésicos. Químicamente, es una mezcla racémica, lo que significa que contiene partes iguales de dos enantiómeros, que pueden exhibir diferentes actividades farmacológicas. El clorhidrato de nefopam se administra típicamente en su forma de sal clorhidrato, mejorando su solubilidad y estabilidad. El compuesto es conocido por su relativamente baja incidencia de efectos secundarios en comparación con los opioides, lo que lo convierte en una alternativa valiosa en el manejo del dolor. Sin embargo, aún puede causar algunos efectos adversos, incluyendo náuseas y mareos. Al igual que con cualquier medicamento, su uso debe ser guiado por un profesional de la salud, considerando las necesidades individuales del paciente y las posibles interacciones con otros medicamentos.
Fórmula:C17H19NO·ClH
InChI:InChI=1S/C17H19NO.ClH/c1-18-11-12-19-17(14-7-3-2-4-8-14)16-10-6-5-9-15(16)13-18;/h2-10,17H,11-13H2,1H3;1H
Clave InChI:InChIKey=CNNVSINJDJNHQK-UHFFFAOYSA-N
SMILES:CN1CC=2C(C(OCC1)C3=CC=CC=C3)=CC=CC2.Cl
Sinónimos:- 1H-2,5-Benzoxazocine, 3,4,5,6-tetrahydro-5-methyl-1-phenyl-, hydrochloride
- 1H-2,5-Benzoxazocine, 3,4,5,6-tetrahydro-5-methyl-1-phenyl-, hydrochloride (1:1)
- 3,4,5,6-Tetrahydro-5-Methyl-1-Phenyl-1H-2,5-Benzoxazocine Hydrochloride
- 3-Methyl-7-Phenyl-6-Oxa-3-Azabicyclo[6.4.0]Dodeca-8,10,12-Triene Hydrochloride
- 5-methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocin-5-ium chloride
- Acupan
- Fenazoxine
- Fenazoxine hydrochloride
- Nefopam HCl
- R 738
- Nefopam hydrochloride
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Encontrado 16 productos.
Nefopam Hydrochloride
CAS:Fórmula:C17H19NO·HClPureza:>98.0%(T)(HPLC)Forma y color:White to Almost white powder to crystalPeso molecular:289.805-Methyl-1-phenyl-3,4,5,6-tetrahydro-1H-benzo[f][1,4]oxazocine hydrochloride
CAS:Pureza:95.0%Forma y color:SolidPeso molecular:289.79998779296875(±)-Nefopam (hydrochloride)
CAS:Fórmula:C17H20ClNOPureza:98%Forma y color:SolidPeso molecular:289.7998Nefopam hydrochloride
CAS:Nefopam hydrochloride (Nefopam HCl) is the hydrochloride salt form of nefopam, a centrally-acting, non-opioid benzoxazocine with analgesic activity.Fórmula:C17H20ClNOPureza:99.32% - 99.85%Forma y color:SolidPeso molecular:289.8Nefopam hydrochloride
CAS:Fórmula:C17H19NO·HClPureza:≥ 98.0%Forma y color:White to off-white or beige powderPeso molecular:289.80Nefopam HCl
CAS:Fórmula:C17H19NO·HClForma y color:White To Off-White SolidPeso molecular:253.35 36.46Nefopam-d4 HCl
CAS:Fórmula:C17H15D4NO·HClForma y color:White To Off-White SolidPeso molecular:257.37 36.46Nefopam Hydrochloride
CAS:Producto controladoFórmula:C17H19NO·ClHForma y color:NeatPeso molecular:289.80Nefopam Hydrochloride
CAS:Producto controlado<p>Applications A cyclized analog of orphenadrine and diphenhydramine; representative of a new class of centrally acting skeletal muscle relaxants, the benzoxazocines. Analgesic; antidepressant.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bassett, et al.: Br. J. Pharmacol., 37, 69 (1969), Klohs, et al.: Arzneim.-Forsch., 22, 132 (1972), Hell, et al.: Drugs, 19, 249 (1980),<br></p>Fórmula:C17H19NO·ClHForma y color:White To Off-WhitePeso molecular:289.80Nefopam HCl - Bio-X ™
CAS:Nefopam is a non-narcotic analgesic drug that has been used in the treatment of chronic pain. It belongs to the class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs). Nefopam is also a nasal drug that relieves pain by blocking neurokinin 1 receptor, which reduces the production of prostaglandins. Nefopam acts in the brain and spinal cord to relieve pain through different mechanisms such as antinociceptive effects from triple monoamine reuptake inhibition, and antihyperalgesic activity through modulation of glutamatergic transmission.Fórmula:C17H19NO·HClPureza:Min. 95%Forma y color:PowderPeso molecular:289.8 g/molNefopam hydrochloride
CAS:<p>3,4,5,6-Tetrahydro-5-methyl-1-phenyl-1H-2,5-benzoxazocine hydrochloride (THPP) is a drug that is used as an analgesic and anti-inflammatory agent. THPP interacts with nonsteroidal anti-inflammatory drugs (NSAIDs) to cause neuronal death. It has been shown to inhibit the plate test for prostaglandin synthesis in human erythrocytes. The disulfide bond between cysteine residues on the protein molecule is susceptible to oxidative cleavage by reactive oxygen species from reactive oxygen species such as hydrogen peroxide and lipid peroxidation products. This can lead to the formation of a thiolate ion and a sulfenic acid intermediate. THPP is also known to produce chronic oral toxicity in rats at doses of 837 mg/kg/day for two months. A chemiluminescence method was used to measure the reaction</p>Fórmula:C17H20ClNOPureza:Min. 95%Forma y color:PowderPeso molecular:289.8 g/molN-Hydroxymethyl Nefopam N-Oxide
CAS:Fórmula:C17H19NO3Forma y color:White To Off-White SolidPeso molecular:285.35Ref: 4Z-N-3710
Producto descatalogado
![5-Methyl-1-phenyl-3,4,5,6-tetrahydro-1H-benzo[f][1,4]oxazocine hydrochloride](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb%2FF241971.jpg&w=3840&q=75)
