CAS 2353493-69-1

PRO-6E

CAS: 2353493-69-1

PRO-6E is an orally active, Cereblon ligand-based PROTAC that promotes MET degradation, achieving up to 81.9% effectiveness at a concentration of 1 μM in MKN-45 cells. It demonstrates tumor growth inhibition both in vivo and in vitro, alongside inducing cell apoptosis and cell cycle arrest.

Fórmula: C₄₂H₄₄Cl₂FN₇O₇

Forma y color: Solid

Peso molecular: 848.75

Ref: TM-T84709