CAS 2361-96-8

Éster etílico de acetil-L-fenilalanina

Descripción:

Éster etílico de acetil-L-fenilalanina, con el número CAS 2361-96-8, es un derivado éster del aminoácido fenilalanina. Este compuesto presenta un grupo acetilo unido al grupo amino de la fenilalanina, junto con un grupo éster etílico en el extremo del ácido carboxílico. Típicamente es un sólido cristalino blanco a blanco sucio, soluble en disolventes orgánicos como el etanol y el metanol, pero menos soluble en agua. La presencia del grupo acetilo mejora su lipofilia, lo que puede influir en su actividad biológica y características de absorción. Éster etílico de acetil-L-fenilalanina se estudia a menudo en el contexto de la síntesis de péptidos y como un posible intermedio en la producción de productos farmacéuticos. Sus características estructurales le permiten participar en varias reacciones químicas, lo que lo convierte en un compuesto valioso en la síntesis orgánica y la química medicinal. Además, debido a su naturaleza de aminoácido, puede exhibir algunas actividades biológicas, aunque las aplicaciones específicas pueden variar según la investigación y el desarrollo en curso.

Fórmula: C₁₃H₁₇NO₃

InChI: InChI=1S/C13H17NO3/c1-3-17-13(16)12(14-10(2)15)9-11-7-5-4-6-8-11/h4-8,12H,3,9H2,1-2H3,(H,14,15)/t12-/m0/s1

Clave InChI: InChIKey=YIVZYFDBEPMPNL-LBPRGKRZSA-N

SMILES: [C@H](CC1=CC=CC=C1)(C(OCC)=O)NC(C)=O

Sinónimos:

• <span class="text-smallcaps">L</span>-N-Acetylphenylalanine ethyl ester
• <span class="text-smallcaps">L</span>-Phenylalanine, N-acetyl-, ethyl ester
• Ac-Phe-OEt
• Acetyl-<span class="text-smallcaps">L</span>-phenylalanine ethyl ester
• Acetylphenylalanine ethyl ester
• Alanine, N-acetyl-3-phenyl-, ethyl ester, <span class="text-smallcaps">L</span>-
• Ethyl N-acetyl-<span class="text-smallcaps">L</span>-phenylalaninate
• N-Acetyl-<span class="text-smallcaps">L</span>-phenylalanine ethyl ester
• N-Acetylphenylalanine ethyl ester
• ethyl N-acetyl-3-phenyl-L-alaninate
• ethyl N-acetyl-L-phenylalaninate
• ethyl N-acetylphenylalaninate
• L-Phenylalanine, N-acetyl-, ethyl ester
• N-Acetyl-L-phenylalanine ethyl ester
• Acetyl-L-phenylalanine ethyl ester

(S)-Ethyl 2-acetamido-3-phenylpropanoate

CAS: 2361-96-8

Fórmula: C₁₃H₁₇NO₃

Pureza: 98%

Forma y color: Solid

Peso molecular: 235.2790

Ref: IN-DA003SP2

N-Acetyl-L-Phenylalanine Ethyl Ester

CAS: 2361-96-8

N-Acetyl-L-Phenylalanine Ethyl Ester

Pureza: 98%

Peso molecular: 235.28g/mol

Ref: 54-OR1014236

Ac-Phe-OEt

CAS: 2361-96-8

Fórmula: C₁₃H₁₇NO₃

Pureza: >98.0%(HPLC)

Forma y color: White to Light yellow powder to crystal

Peso molecular: 235.28

Ref: 3B-A3498

Ac-Thz-Tle-Leu-Gln-MCA

CAS: 2361-96-8

A prototype fluorogenic substrate targeting the SARS-CoV and SARS-CoV-2 Main Protease (Mpro). The main protease (Mpro­), also called endopeptidase C30 or 3C-like proteinase (3CLpro), controls viral replication activities and is a prime therapeutical target. Both substrates and inhibitors of SARS-CoV-2 Mpro are currently of interest to researchers of the coronavirus. This product can be used as a Prototype Fluorescence Substrate for SARS-CoV Mpro/SARS-CoV-2 Mpro Proteases.

Fórmula: C₁₃H₁₇NO₃

Pureza: Min. 95%

Peso molecular: 235.28 g/mol

Ref: 3D-SFP-3251-V

Acetyl-L-phenylalanine Ethyl Ester

Producto controlado

CAS: 2361-96-8

Applications Acetyl-L-phenylalanine ethyl ester is a derivative of L-Phenylalanine (P319415), a nonpolar, essential amino acid that naturally occurs in the human body and is also used to treat patients with depression. Acetyl-L-phenylalanine ethyl ester is also used to inhibit pepsin-catalyzed reactions.
References Auer, H. & Doty, P.: Biochemistry, 5, 1708 (1966); Birkmayer, W., et al.: J. Neural Transm., 59, 81 (1984); Borison, R., et al.: Res. Commun. Chem. Path., 21, 363 (1978); Kitson, T., et al.: Biochem. J., 122, 241 (1971)

Fórmula: C₁₃H₁₇NO₃

Forma y color: Neat

Peso molecular: 235.28

Ref: TR-A187950

(S)-Ethyl 2-acetamido-3-phenylpropanoate

CAS: 2361-96-8

Fórmula: C₁₃H₁₇NO₃

Pureza: 98%

Forma y color: Solid

Peso molecular: 235.283

Ref: 10-F224477

Acetyl-L-phenylalanine ethyl ester

CAS: 2361-96-8

Acetyl-L-phenylalanine ethyl ester is a substrate analogue that competes with the natural substrate, L-phenylalanine, for binding sites on the enzyme. The acetyl group of acetyl-L-phenylalanine ethyl ester reacts with the amino acid residues of L-phenylalanine to form covalent linkages. This prevents the enzyme from catalyzing reactions involving L-phenylalanine and other substrates. Acetyl-L-phenylalanine ethyl ester binds to cytochalasin B and inhibits its ability to bind to actin filaments, thus inhibiting cell growth. The high salt concentration in this experiment allows for separation of the protein from other cellular components by sephadex g-100 chromatography. Kinetic studies have been done on human serum albumin, which is a protein that can bind acetyl-L-phenylalanine ethl ester with a

Fórmula: C₁₃H₁₇NO₃

Pureza: Min. 95%

Peso molecular: 235.28 g/mol

Ref: 3D-FA47441

Ac-Phe-OEt

CAS: 2361-96-8

Ac-Phe-OEt is a covalently conjugated bifunctional peptide that has been synthesized by linking the amino acid phenylalanine to the amino acid ethyl ester of oleic acid. Ac-Phe-OEt exhibits a high affinity for bacterial serine proteases (Km=0.1 μM) and lysine residues (Ki=4 μM). This peptide also binds to immobilized cytochalasin, which prevents the formation of amyloid fibrils. Ac-Phe-OEt can be used in enzyme catalysis as an inhibitor or competitive inhibitor, as well as being immobilized on surfaces. The kinetic data suggests that Ac-Phe-OEt competes with lysine residues for binding to bacterial serine proteases and inhibits their activity.

Fórmula: C₁₃H₁₇NO₃

Pureza: Min. 95%

Peso molecular: 235.28 g/mol

Ref: 3D-SFE-3006