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CAS 2413986-35-1

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  • RORγt Inverse agonist 10
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    RORγt Inverse agonist 10

    CAS:
    <p>RORγt Inverse agonist 10 is a highly potent, orally bioavailable compound that acts as an antagonist for the retinoic acid receptor-related orphan nuclear receptor gamma t (RORγt). With an IC50 of 51 nM, it effectively inhibits RORγt activity, a key transcription factor regulating genes linked to psoriasis pathogenesis, including [IL-17A], [IL-22], and [IL-23R].</p>
    Fórmula:C25H26F6N6O3
    Forma y color:Solid
    Peso molecular:572.512

    Ref: TM-T40043

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