CAS 24305-27-9
:Hormona liberadora de tirotropina
Descripción:
La hormona liberadora de tirotropina (TRH), también conocida como Hormona liberadora de tirotropina, es una hormona tripeptídica compuesta por tres aminoácidos: ácido pirrolidínico, histidina y prolina. Juega un papel crucial en la regulación de la función tiroidea al estimular la liberación de la hormona estimulante de tiroides (TSH) de la glándula pituitaria anterior. La TRH se sintetiza en el hipotálamo y está involucrada en el eje hipotálamo-hipofisario-tiroideo, influyendo en los procesos metabólicos y la homeostasis energética. El número CAS 24305-27-9 identifica específicamente este péptido, que se encuentra típicamente en forma sólida o liofilizada para aplicaciones de investigación y terapéuticas. La TRH es soluble en agua y se puede administrar por diversas vías, incluyendo inyección intravenosa o subcutánea. Su actividad biológica se media a través de receptores específicos en la glándula pituitaria, lo que lleva a efectos posteriores en la producción de hormonas tiroideas. Además, se ha estudiado la TRH por sus posibles roles en diversas condiciones fisiológicas y patológicas, incluidos sus efectos sobre el estado de ánimo y las respuestas al estrés.
Fórmula:C16H22N6O4
InChI:InChI=1S/C16H22N6O4/c17-14(24)12-2-1-5-22(12)16(26)11(6-9-7-18-8-19-9)21-15(25)10-3-4-13(23)20-10/h7-8,10-12H,1-6H2,(H2,17,24)(H,18,19)(H,20,23)(H,21,25)/t10-,11-,12-/m0/s1
Clave InChI:InChIKey=XNSAINXGIQZQOO-SRVKXCTJSA-N
SMILES:C([C@H](CC1=CN=CN1)NC(=O)[C@@H]2CCC(=O)N2)(=O)N3[C@H](C(N)=O)CCC3
Sinónimos:- (Pyro)-<span class="text-smallcaps">L</smallcap>-glutamic acid-<smallcap>L</smallcap>-histidine-<smallcap>L</span>-proline-NH<sub>2</sub>
- (Pyro)-L-glutamic acid-L-histidine-L-proline-NH2
- 252: PN: WO2010033207 SEQID: 378 claimed protein
- 5-Oxo-<span class="text-smallcaps">L</smallcap>-prolyl-<smallcap>L</smallcap>-histidyl-<smallcap>L</span>-prolinamide
- 83: PN: US20090175821 PAGE: 403 claimed protein
- <span class="text-smallcaps">L</smallcap>-Prolinamide, 5-oxo-<smallcap>L</smallcap>-prolyl-<smallcap>L</span>-histidyl-
- <span class="text-smallcaps">L</smallcap>-Pyroglutamyl-<smallcap>L</smallcap>-histidyl-<smallcap>L</span>-prolinamide
- <span class="text-smallcaps">L</smallcap>-Pyroglutamyl-<smallcap>L</smallcap>-histidyl-<smallcap>L</span>-proline amide
- Abbott 38579
- Antepan
- Fda 1725
- L-Pyroglutamyl-L-histidyl-L-prolinamide
- L-Pyroglutamyl-L-histidyl-L-proline amide
- Lopremone
- Prem
- Protirelin
- Protirelina
- Protireline
- Relefact TRH
- Rifathyroin
- Rifotironin
- Ro 8-6270/9
- Stimu TSH
- Synthetic TRF
- Synthetic TRH
- Synthetic TSH-releasing factor
- Synthetic TSH-releasing hormone
- Synthetic thyrotropin-releasing factor
- Synthetic thyrotropin-releasing hormone
- TRF
- TRH
- TSH-releasing factor
- TSH-releasing hormone
- Thypinone
- Thyrefact
- Thyroid releasing hormone
- Thyroid-stimulating hormone-releasing factor
- Thyroliberin
- Thyrotropic hormone-releasing factor
- Thyrotropic hormone-releasing hormone
- Thyrotropic releasing hormone
- Thyrotropic-releasing factor
- Thyrotropin-releasing factor
- Thyrotropin-releasing hormone
- Tsh-Rf
- L-Prolinamide, 5-oxo-L-prolyl-L-histidyl-
- Ver más sinónimos
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Encontrado 14 productos.
Thyrotropin-Releasing Hormone
CAS:<p>Thyrotropin-Releasing Hormone</p>Fórmula:C16H22N6O4Forma y color:White, Lyophilized powderPeso molecular:362.38TRH
CAS:TRH exhibits a variety of biological effects, when injected into humans or animals. Its physiological role appears to be the stimulation of thyrotropin (TSH) and prolactin (PRL) release from the anterior pituitary. Though it was first identified in the hypothalamus as a regulator of the pituitary-thyroid axis, TRH was detected as well by Luo et al. in pancreatic β-cells co-localized with insulin. Application of the hormone reverted hyperglycemia in rats. Moreover, TRH plays an important role in the control of human hair-growth and hair follicle pigmentation.Fórmula:C16H22N6O4Pureza:98.6%Forma y color:Whitish PowderPeso molecular:362.39L-Pyroglutamyl-L-Histidyl-L-Prolinamide
CAS:L-Pyroglutamyl-L-Histidyl-L-ProlinamidePureza:98%Peso molecular:362.38g/molProtirelin
CAS:Protirelin (Thyroliberin) is a tripeptide that stimulates the release of thyrotropin and prolactin.Fórmula:C16H22N6O4Pureza:99.76%Forma y color:White Or Almost White PowderPeso molecular:362.38Protirelin
CAS:Fórmula:C16H22N6O4Pureza:95%~99%Forma y color:White to Off-white PowderPeso molecular:362.38Thyrotropin-Releasing Hormone
CAS:Producto controlado<p>Applications Thyrotropin-Releasing Hormone is a hypothalamic hypophysiotropic neuropeptide, which has the ability to stimulate the release of thyroid-stimulating hormone in mammals. It is proven that Thyrotropin-Releasing Hormone can be used to accelerate wound healing.<br>References Kanasaki, H., et al.: Neuropeptides., 54, 73 (2015); Nie, C., et al.: J. Surg. Res., 189, 364 (2014);<br></p>Fórmula:C16H22N6O4Forma y color:Off-WhitePeso molecular:362.38L-Pyroglutamyl-L-histidyl-L-prolinamide
CAS:<p>L-Pyroglutamyl-L-histidyl-L-prolinamide (PGC) is a pyrrolidine that is used for the treatment of neurologic disorders. It has been shown to be effective in treating depression and a number of other neurologic disorders, including Parkinson's disease, Alzheimer's disease, and epilepsy. PGC has also been shown to have an antidepressant effect in women with depression who are pregnant or have recently given birth. In addition, it has been found to be clinically effective in the treatment of symptoms associated with Parkinson’s Disease. PGC is not absorbed into the bloodstream and must be injected directly into muscle tissue or fat cells in order to produce its therapeutic effects.</p>Fórmula:C16H22N6O4Pureza:Min. 95%Forma y color:White PowderPeso molecular:362.38 g/molThyrotropin Releasing Hormone (TRH) (Human, Ovine, Porcine, Rat)
CAS:Thyrotropin releasing hormone (TRH) is a peptide that is produced in the hypothalamus. It has various functions, including being an activator of thyroid stimulating hormone (TSH) and releasing growth hormone from the anterior pituitary gland. TRH also has anti-inflammatory effects and is used as a research tool in cell biology. TRH binds to receptors on cells and can activate ion channels, which causes an influx of calcium ions into cells. This leads to the activation of protein kinases, which are important in cell signaling pathways. TRH also interacts with other proteins, such as receptor tyrosine kinases and G-protein coupled receptors.Fórmula:C16H22N6O4Pureza:Min. 95%Peso molecular:362.38 g/molThyrotropin Releasing Hormone (TRH) (Human, Ovine, Porcine, Rat)
CAS:<p>Thyrotropin Releasing Hormone (TRH) is a hormone that stimulates the release of thyroid hormones. TRH has been used to diagnose and treat conditions such as autoimmune diseases, infectious diseases, and thyroid disease. It is also used in the treatment of patients with hypothyroidism who are not responding to levothyroxine therapy. TRH is administered intravenously or intramuscularly. This drug is primarily used for diagnostic purposes in women who have symptoms of hyperthyroidism but normal serum levels of TSH and thyroxine levels. TRH administration can result in a rise in serum prolactin levels, which may be useful for diagnosis of the condition hyperprolactinemia.</p>Fórmula:C16H22N6O4•H2OPureza:Min. 95%Peso molecular:380.4 g/mol
