CAS 245443-52-1

L-Fenilalaninamida, glicil-L-tirosil-L-prolilglicil-L-lisil-

Descripción:

L-fenilalaninamida, glicil-L-tirosil-L-prolilglicil-L-lisina es un compuesto peptídico caracterizado por su secuencia específica de aminoácidos. Esta sustancia es un derivado de la fenilalanina, un aminoácido esencial, y forma parte de una cadena peptídica más grande que incluye glicina, tirosina, prolina y lisina. La presencia de estos aminoácidos contribuye a sus propiedades estructurales y funcionales, influyendo en su solubilidad, estabilidad y potencial actividad biológica. Los péptidos como este a menudo exhiben interacciones únicas con sistemas biológicos, lo que los hace de interés en campos como la bioquímica y la farmacología. El número CAS 245443-52-1 identifica de manera única este compuesto, facilitando su reconocimiento en la literatura científica y bases de datos. Si bien las aplicaciones específicas pueden variar, los compuestos de esta naturaleza a menudo se exploran por sus roles en vías de señalización, potencial terapéutico o como herramientas de investigación para entender las interacciones y funciones de las proteínas. En general, las características de este péptido sugieren una compleja interacción de propiedades bioquímicas que justifican una investigación más profunda.

Fórmula: C₃₃H₄₆N₈O₇

Sinónimos:

• H-Gly-Tyr-Pro-Gly-Lys-Phe-Nh2

PAR-4 (1-6) amide (mouse)

CAS: 245443-52-1

Protease-activated receptor-4 activating peptide derived from murine PAR-4. GYPGKF-amide was able to cause rat platelet aggregation with an EC₅₀ value of 40 µM. Its effect on leucocyte rolling and adherence points at a role of PAR-4 in mediating proinflammatory processes.

Fórmula: C₃₃H₄₆N₈O₇

Pureza: 98.5%

Forma y color: Whitish Powder

Peso molecular: 666.78

Ref: 01-4035649

H-Gly-Tyr-Pro-Gly-Lys-Phe-NH2

CAS: 245443-52-1

This is a synthetic peptide that mimics the endogenous human epidermal growth factor (EGF) and binds to the toll-like receptor. It has been shown to stimulate physiological function in experimental models of bowel disease and cardiac disease, as well as cancer tissues. The peptide also binds to the guanine nucleotide-binding protein, polymerase chain reaction, and inflammatory bowel disease genes. In vivo studies have confirmed that this peptide enhances the production of EGF in maternal blood and stimulates squamous carcinoma growth in an animal model.

Fórmula: C₃₃H₄₆N₈O₇

Pureza: Min. 95%

Peso molecular: 666.78 g/mol

Ref: 3D-PAR-3672-PI

PAR-4 (1-6) amide (mouse)

CAS: 245443-52-1

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Fórmula: C₃₃H₄₆N₈O₇

Peso molecular: 666.78 g/mol

Ref: 3D-PP50225

PAR-4 Agonist (Mouse)

CAS: 245443-52-1

Thrombin is the main effector of the coagulation cascade- it is a serine protease. Thrombin binds to active protease activated receptor (PAR) which belongs to a subfamily of G-protein coupled receptors (GPCR). Thrombin activation of mouse PAR-4 reveals an amino terminus sequence of GYPGKF. This is the natural ligand for PAR-4. GYPGKF binds internally to the receptor and leads to signalling activation. Identification of GYPGKF as a PAR-4 agonist has allowed better understand of the function of PAR. Addition of GYPGKF to PAR-4 expressing cell lines achieved 55% of the maximal response of thrombin. GYPGKF can provide understanding of PAR-4 and a template for more potent agonists.

Fórmula: C₃₃H₄₆N₈O₇

Forma y color: Powder

Peso molecular: 666.3 g/mol

Ref: 3D-CRB1000559

PAR-4 (1-6) amide (mouse) trifluoroacetate salt

CAS: 245443-52-1

PAR-4 (1-6) amide (mouse) trifluoroacetate salt H-Gly-Tyr-Pro-Gly-Lys-Phe-NH2 trifluoroacetate salt is a guanine nucleotide binding protein that belongs to the PAR family of proteins. It is expressed in wild type mice and binds to the cytosolic calcium, which regulates polymerase chain reaction. PAR-4 (1-6) amide (mouse) trifluoroacetate salt H-Gly-Tyr-Pro-Gly-Lys-Phe NH2 trifluoroacetate salt can be used as a potential drug target for epidermal growth factor. It has been shown to activate transcription polymerase chain and transcriptase polymerase chain during transcriptional regulation of messenger RNA.

Fórmula: C₃₃H₄₆N₈O₇

Pureza: Min. 95%

Peso molecular: 666.77 g/mol

Ref: 3D-FP109705

Protease-Activated Receptor-4

CAS: 245443-52-1

Protease-Activated Receptor-4 (PAR4) is a proteinase-activated receptor-4 agonist used in antiplatelet therapy.

Fórmula: C₃₃H₄₆N₈O₇

Pureza: 98%

Forma y color: Solid

Peso molecular: 666.77

Ref: TM-T7380