CAS 2498-41-1

5-Metil dCMP

Descripción:

5-Metil dCMP, o 5-metil-2'-desoxicitidina monofosfato, es un monofosfato de nucleósido que juega un papel significativo en la estructura del ADN. Es un derivado de la desoxicitidina, donde un grupo metilo está unido al quinto carbono del anillo de pirimidina. Esta modificación puede influir en la expresión génica y a menudo se estudia en el contexto de la epigenética, particularmente en relación con los patrones de metilación del ADN. La presencia del grupo metilo puede afectar la estabilidad de la molécula de ADN y sus interacciones con proteínas, impactando así procesos celulares como la replicación y la transcripción. 5-Metil dCMP también está involucrado en diversas vías bioquímicas, incluidas las relacionadas con el metabolismo de nucleótidos. Su número CAS, 2498-41-1, se utiliza para la identificación en bases de datos químicas. Como entidad química, se caracteriza típicamente por su fórmula molecular, que refleja sus átomos constituyentes, y sus propiedades físicas, que pueden incluir solubilidad y estabilidad bajo diversas condiciones. Comprender sus características es esencial para la investigación en biología molecular y genética.

Fórmula: C₁₀H₁₆N₃O₇P

InChI: InChI=1/C10H16N3O7P/c1-5-3-13(10(15)12-9(5)11)8-2-6(14)7(20-8)4-19-21(16,17)18/h3,6-8,14H,2,4H2,1H3,(H2,11,12,15)(H2,16,17,18)/t6-,7+,8+/m0/s1

Clave InChI: InChIKey=RGDVNLHBCKWZDA-XLPZGREQSA-N

SMILES: O=C1N([C@@H]2O[C@H](COP(=O)(O)O)[C@@H](O)C2)C=C(C)C(N)=N1

Sinónimos:

• 2'-Deoxy-5-Methylcytidine 5'-(Dihydrogen Phosphate)
• 2'-Deoxy-5-methylcytidine 5'-monophosphate
• 2′-Deoxy-5-methyl-5′-cytidylic acid
• 2′-Deoxy-5-methylcytidine 5′-phosphate
• 5-Methyl dCMP
• 5-Methyl-deoxycytidylic acid
• 5-Methyldeoxycytidine monophosphate
• 5-Methyldeoxycytidylic acid
• 5′-Cytidylic acid, 2′-deoxy-5-methyl-
• Cytidine, 2′-deoxy-5-methyl-, 5′-(dihydrogen phosphate)
• Cytidine, 2′-deoxy-5-methyl-, 5′-phosphate
• Deoxy-5-methylcytidylic acid
• 5-methyl-2'-deoxycytidine 5'-monophosphate
• 2''-Deoxy-5-methylcytidine-5''-phosphoric acid
• 5-Methyldeoxycytidine-5'-monophosphoric acid
• 5-Methyl-2'-deoxy-5'-cytidylic acid
• 5-mdCMP
• 5-MedCTP
• 5-MedCT

5'-Cytidylic acid, 2'-deoxy-5-methyl-

CAS: 2498-41-1

Fórmula: C₁₀H₁₆N₃O₇P

Pureza: 95%

Forma y color: Solid

Peso molecular: 321.2237

Ref: IN-DA002Q2V

5-Methyl-2'-deoxycytidine 5'-monophosphate

CAS: 2498-41-1

5-Methyl-2'-deoxycytidine 5'-monophosphate

Pureza: 95%

Peso molecular: 321.23g/mol

Ref: 54-OR1070343

2''-Deoxy-5-methylcytidine-5''-monophosphate disodium salt

CAS: 2498-41-1

Fórmula: C₁₀H₁₄N₃O₇PNa₂

Pureza: (HPLC) ≥ 97.0%

Forma y color: White to off-white powder

Peso molecular: 365.19

Ref: 7W-GN7411

2'-Deoxy-5-methylcytidine-5'-monophosphate disodium

CAS: 2498-41-1

2'-Deoxy-5-methylcytidine-5'-monophosphate disodium (2D5MCP) is a nucleoside analog that inhibits the synthesis of DNA. It is used in the treatment of cervical cancer and other cancers that are dependent on DNA synthesis. 2D5MCP works by binding to and inhibiting the activity of an enzyme called DNA polymerase, which is needed for DNA replication. This drug also has been shown to inhibit fatty acid synthase enzymes and surface glycoprotein enzymes, which may be responsible for its anti-cancer effects. 2D5MCP has been shown to have an effective dose range between 50 and 150 mg/kg, with no significant side effects seen at doses up to 300 mg/kg. 2D5MCP does not bind to plasma proteins or erythrocytes, so it can be administered intravenously without risk of tissue damage caused by osmotic lysis.

Fórmula: C₁₀H₁₄N₃O₇PNa₂

Pureza: Min. 95%

Forma y color: White Powder

Peso molecular: 365.19 g/mol

Ref: 3D-ND10012

((2R,3S,5R)-5-(4-amino-5-methyl-2-oxopyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate

CAS: 2498-41-1

Pureza: 95%

Peso molecular: 321.2260132

Ref: 10-F772402