CAS 25507-04-4

Clindamicina palmitato hidrocloruro

Descripción:

Clindamicina palmitato hidrocloruro es un antibiótico semisintético derivado de la lincomicina, utilizado principalmente para tratar diversas infecciones bacterianas, particularmente aquellas causadas por bacterias anaerobias y ciertas cepas de estreptococos. Se caracteriza por su forma de polvo cristalino blanco a blanco amarillento, que es soluble en agua y exhibe estabilidad bajo condiciones normales de almacenamiento. La sustancia funciona inhibiendo la síntesis de proteínas bacterianas, ejerciendo así sus efectos antimicrobianos. Clindamicina palmitato hidrocloruro se administra a menudo en formulaciones orales, lo que lo hace adecuado para su uso pediátrico debido a su éster de palmitato, que mejora su sabor y palatabilidad. La forma de sal hidrocloruro mejora su solubilidad y biodisponibilidad. Al igual que con cualquier antibiótico, es esencial usar Clindamicina palmitato hidrocloruro de manera juiciosa para prevenir el desarrollo de resistencia a los antibióticos. Los efectos secundarios potenciales pueden incluir trastornos gastrointestinales y reacciones alérgicas, lo que requiere un monitoreo cuidadoso durante el tratamiento. En general, es un agente terapéutico valioso en el manejo de infecciones específicas, particularmente en pacientes alérgicos a la penicilina.

Fórmula: C₃₄H₆₃ClN₂O₆S·ClH

InChI: InChI=1S/C34H63ClN2O6S.ClH/c1-6-8-9-10-11-12-13-14-15-16-17-18-19-21-27(38)42-32-30(40)29(39)31(43-34(32)44-5)28(24(3)35)36-33(41)26-22-25(20-7-2)23-37(26)4;/h24-26,28-32,34,39-40H,6-23H2,1-5H3,(H,36,41);1H/t24-,25+,26-,28+,29+,30-,31+,32+,34+;/m0./s1

Clave InChI: InChIKey=GTNDZRUWKHDICY-DJHAJVGHSA-N

SMILES: [C@@H](NC(=O)[C@@H]1C[C@@H](CCC)CN1C)([C@H](C)Cl)[C@]2(O[C@H](SC)[C@H](OC(CCCCCCCCCCCCCCC)=O)[C@@H](O)[C@H]2O)[H].Cl

Sinónimos:

• <span class="text-smallcaps">L</smallcap>-threo-<smallcap>D</smallcap>-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-4-propyl-<smallcap>L</span>-2-pyrrolidinecarboxamido)-1-thio-, 2-palmitate, monohydrochloride, trans-α-
• <span class="text-smallcaps">L</smallcap>-threo-α-<smallcap>D</span>-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-, 2-hexadecanoate, monohydrochloride, (2S-trans)-
• <span class="text-smallcaps">L</smallcap>-threo-α-<smallcap>D</span>-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-, 2-hexadecanoate, monohydrochloride
• Cleocin Pediatric
• Clindamycin 2-palmitate hydrochloride
• Clindamycin palmitate hydrochloride
• Palmitic acid, 2-ester with methyl 7-chloro-6,7,8-trideoxy-6-(trans-1-methyl-4-propyl-<span class="text-smallcaps">L</smallcap>-2-pyrrolidinecarboxamido)-1-thio-<smallcap>L</smallcap>-threo-α-<smallcap>D</span>-galacto-octopyranoside monohydrochloride
• [(2R,3R,4S,5R,6R)-6-[2-chloro-1-[[(2S,4R)-1-methyl-4-propyl-pyrrolidine-2-carbonyl]amino]propyl]-4,5-dihydroxy-2-methylsulfanyl-tetrahydropyran-3-yl] hexadecanoate hydrochloride
• methyl 7-chloro-6,7,8-trideoxy-2-O-hexadecanoyl-6-{[(4R)-1-methyl-4-propyl-L-prolyl]amino}-1-thio-L-threo-alpha-D-galacto-octopyranoside hydrochloride (1:1)
• methyl 7-chloro-6,7,8-trideoxy-2-O-hexadecanoyl-6-{[(4R)-1-methyl-4-propyl-L-prolyl]amino}-1-thio-beta-L-erythro-octopyranoside hydrochloride (1:1)
• L-threo-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-, 2-palmitate, monohydrochloride, trans-α-
• L-threo-α-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-, 2-hexadecanoate, monohydrochloride
• L-threo-α-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-, 2-hexadecanoate, monohydrochloride, (2S-trans)-

Clindamycin Palmitate Hydrochloride

CAS: 25507-04-4

Antibiotics nesoi

Fórmula: C₃₄H₆₃ClN₂O₆S·HCl

Forma y color: White Off-White Powder

Peso molecular: 662.40954

Ref: 45-1137005

Clindamycin 2-Palmitate

CAS: 25507-04-4

Fórmula: C₃₄H₆₃ClN₂O₆S·HCl

Forma y color: White To Off-White Solid

Peso molecular: 663.41 36.46

Ref: 4Z-C-5026

Clindamycin palmitate hydrochloride

CAS: 25507-04-4

Clindamycin palmitate hydrochloride (Clindamycin palmitate HCl) is the hydrochloride salt of clindamycin and palmitate, a lincosamide antibiotic.

Fórmula: C₃₄H₆₃ClN₂O₆S·HCl

Pureza: 98%

Forma y color: Solid

Peso molecular: 699.85

Ref: TM-T6449

Clindamycin Palmitate Hydrochloride

CAS: 25507-04-4

Forma y color: Neat

Ref: 61-FOR1989.00

Clindamycin Palmitate Hydrochloride

Producto controlado

CAS: 25507-04-4

Fórmula: C₃₄H₆₃ClN₂O₆S·ClH

Forma y color: Neat

Peso molecular: 699.85

Ref: 86-MM1989.00

Clindamycin Palmitate Hydrochloride

Producto controlado

CAS: 25507-04-4

Applications Clindamycin Palmitate is a semi-synthetic antibiotic with high bioavailability. Clindamycin Palmitate is an antibacterial.
References Platzer, D., et al.: J. Pharm. Biomed. Anal., 41, 84 (2006),

Fórmula: C₃₄H₆₃ClN₂O₆S·ClH

Forma y color: Neat

Peso molecular: 699.85

Ref: TR-C580035

Clindamycin Palmitate Hydrochloride

CAS: 25507-04-4

Fórmula: C₃₄H₆₃ClN₂O₆SHCl

Peso molecular: 663.4 : 36.5

Ref: ST-EA-CP-C26050