CAS: 257933-82-7 - Pelitinib

Fórmula: C₂₄H₂₃ClFN₅O₂

InChI: InChI=1S/C24H23ClFN5O2/c1-4-33-22-12-20-17(11-21(22)30-23(32)6-5-9-31(2)3)24(15(13-27)14-28-20)29-16-7-8-19(26)18(25)10-16/h5-8,10-12,14H,4,9H2,1-3H3,(H,28,29)(H,30,32)/b6-5+

Clave InChI: InChIKey=WVUNYSQLFKLYNI-AATRIKPKSA-N

SMILES: N#CC1=CN=C2C=C(OCC)C(=CC2=C1NC3=CC=C(F)C(Cl)=C3)NC(=O)C=CCN(C)C

Sinónimos:

• (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide
• (2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]-3-cyano-7-ethoxyquinolin-6-yl}-4-(dimethylamino)but-2-enamide
• (E)-N-(4-(3-chloro-4-fluorophenylamino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide
• 2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-, (2E)-
• Ekb-569
• Way-Ekb 569

Pelitinib

CAS: 257933-82-7

• Fórmula: C₂₄H₂₃ClFN₅O₂
• Pureza: >97.0%(HPLC)
• Forma y color: White to Light yellow powder to crystal
• Peso molecular: 467.93

Pelitinib

CAS: 257933-82-7

• Fórmula: C₂₄H₂₃ClFN₅O₂
• Peso molecular: 467.92

Pelitinib

CAS: 257933-82-7

Pelitinib (EKB-569) (EKB-569) is an effective irreversible EGFR inhibitor (IC50: 38.5 nM).

• Fórmula: C₂₄H₂₃ClFN₅O₂
• Pureza: 99.86%
• Forma y color: Off-White Solid
• Peso molecular: 467.92

Pelitinib

CAS: 257933-82-7

Applications A tyrosine kinase inhibitor; it is used to prepare formulation for treating primary or …

• Fórmula: C₂₄H₂₃ClFN₅O₂
• Forma y color: Off-White to Pale Yellow Solid
• Peso molecular: 467.92

Pelitinib

CAS: 257933-82-7

EGFR tyrosine kinase inhibitor; pro-apoptotic; antiproliferative in cancer cells

• Fórmula: C₂₄H₂₃ClFN₅O₂
• Pureza: Min. 95%
• Forma y color: Powder
• Peso molecular: 467.92 g/mol

Pelitinib

CAS: 257933-82-7

• Fórmula: C₂₄H₂₃ClFN₅O₂
• Pureza: 98%
• Forma y color: Solid
• Peso molecular: 467.9231