CAS 2627-69-2
:AICAr
Descripción:
AICAr, o 5-aminoimidazol-4-carboxamida ribonucleótido, es un compuesto químico que desempeña un papel significativo en el metabolismo celular, particularmente en la vía de biosíntesis de purinas. Es un precursor de nucleótidos que está involucrado en la síntesis de adenosina monofosfato (AMP). AICAr es conocido por sus efectos potenciales en el metabolismo energético celular y ha sido estudiado por su papel en la activación de la quinasa de proteínas activada por AMP (AMPK), que es crucial para regular la homeostasis energética. El compuesto se investiga a menudo en el contexto de trastornos metabólicos, fisiología del ejercicio y aplicaciones terapéuticas potenciales para condiciones como la obesidad y la diabetes tipo 2. AICAr se caracteriza típicamente por su estructura molecular, que incluye un anillo de imidazol y un componente de ribonucleótido. Su número CAS, 2627-69-2, es un identificador único que facilita la identificación y el estudio de este compuesto en la literatura científica y bases de datos. En general, AICAr es una molécula significativa en bioquímica con implicaciones para la salud y el manejo de enfermedades.
Fórmula:C9H14N4O5
InChI:InChI=1S/C9H14N4O5/c10-7-4(8(11)17)12-2-13(7)9-6(16)5(15)3(1-14)18-9/h2-3,5-6,9,14-16H,1,10H2,(H2,11,17)/t3-,5-,6-,9-/m1/s1
Clave InChI:InChIKey=RTRQQBHATOEIAF-UUOKFMHZSA-N
SMILES:O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(N)=C(C(N)=O)N=C2
Sinónimos:- 1-Ribosyl-4-carboxamido-5-aminoimidazole
- 1-β-<span class="text-smallcaps">D</span>-Ribofuranosyl-5-amino-4-imidazolecarboxamide
- 1H-Imidazole-4-carboxamide, 5-amino-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
- 5-Amino-1-beta-ribofuranosyl-imidazole-4-carboxamide
- 5-Amino-1-ribosyl-4-imidazolecarboxamide
- 5-Amino-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-imidazole-4-carboxamide
- 5-Amino-1-β-<span class="text-smallcaps">D</span>-ribofuranosylimidazole-4-carboxamide
- 5-Amino-1beta-D-ribofuranosylimidazole-4-carboxamide
- 5-Amino-4-imidazolecarboxamide ribofuranoside
- 5-Amino-4-imidazolecarboxamide riboside
- 5-Aminoimidazole-4-carboxamid-1-β-<span class="text-smallcaps">D</span>-ribofuranoside
- 5-Aminoimidazole-4-carboxamide 1-(β-<span class="text-smallcaps">D</span>-ribofuranoside)
- 5-Aminoimidazole-4-carboxamide ribonucleoside
- 5-Aminoimidazole-4-carboxamide riboside
- 5-Aminoimidazole-4-carboxamide-1-§-D-Ribofuranoside
- 5-amino-1-(beta-D-ribofuranosyl)-1H-imidazole-4-carboxamide
- AIC-Riboside
- AICA-riboside
- Acadra
- Aicar
- Arasine
- Gp 1-110
- Imidazole-4-carboxamide, 5-amino-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
- NSC 105823
- 5-Amino-1-β-D-ribofuranosyl-1H-imidazole-4-carboxamide
- 1H-Imidazole-4-carboxamide, 5-amino-1-β-D-ribofuranosyl-
- Ver más sinónimos
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Encontrado 11 productos.
5-Aminoimidazole-4-carboxamide 1-β-D-Ribofuranoside
CAS:Fórmula:C9H14N4O5Pureza:>98.0%(HPLC)Forma y color:White to Light yellow to Light red powder to crystalPeso molecular:258.235-Aminoimidazole-4-carboxamide 1-β-D-ribofuranoside, 98%
CAS:Activator of AMP-activated protein kinase (AMPK)
Fórmula:C9H14N4O5Pureza:98%Peso molecular:258.23AICAR
CAS:AICAR (Acadesine) is an AMPK activator, metabolic regulation, muscle function regulation, anti-cancer effect, neuroprotection. High-Quality, Low-Cost!Fórmula:C9H14N4O5Pureza:98.00% - ≥95%Forma y color:SolidPeso molecular:258.235-Amino-1-(β-D-ribofuranosyl)-1H-imidazole-4-carboxamide
CAS:5-Amino-1-(β-D-ribofuranosyl)-1H-imidazole-4-carboxamideFórmula:C9H14N4O5Pureza:97%Forma y color: off-white to white solidPeso molecular:258.23g/mol5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside
CAS:Applications AICAR is a nucleoside analogue that is able to enter nucleoside pools and is able to significantly increase levels of adenosine during periods of ATP breakdown. Adenosine-regulating agents (ARAs) have been recognized for therapeutic potential in myocardial ischemia. Cardioprotective.
References Mullane, K., et al.: Trends Cardiovasc Med., 3, 227 (1993), Browne, G.J., et al.: J. Biol. Chem., 279, 13, 12220 (2004)Fórmula:C9H14N4O5Forma y color:NeatPeso molecular:258.235-Aminoimidazole-4-carboxamide-1-b-D-ribofuranose
CAS:Acadesine is a purine nucleoside analogue that inhibits the synthesis of ATP in cells. Acadesine blocks phosphorylation of adenosine monophosphate (AMP) to adenosine triphosphate (ATP) by inhibiting the activity of kinase-3, an enzyme involved in the production of ATP. Acadesine also inhibits the release of ATP from muscle cells into the blood stream and preferentially targets kidney cells, thereby reducing renal injury. Acadesine has been shown to be effective at reducing proteinuria and improving renal function in rats with acute kidney injury. Acadesine also has anti-inflammatory properties due to its ability to inhibit proteins that are involved in inflammation.Fórmula:C9H14N4O5Pureza:Min. 98 Area-%Forma y color:PowderPeso molecular:258.23 g/molAICA Riboside
CAS:M04018 - AICA Riboside
Fórmula:C9H14N4O5Pureza:98%Forma y color:SolidPeso molecular:258.2345-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside-15N4
CAS:Producto controladoApplications A labelled nucleoside analogue that is able to enter nucleoside pools and is able to significantly increase levels of adenosine during periods of ATP breakdown. Adenosine-regulating agents (ARAs) have been recognized for therapeutic potential in myocardial ischemia. Cardioprotective.
References Mullane, K., et al.: Trends Cardiovasc Med., 3, 227 (1993), Browne, G.J., et al.: J. Biol. Chem., 279, 13, 12220 (2004)Fórmula:C9H1415N4O5Forma y color:NeatPeso molecular:262.205-Amino-1-β-D-ribofuranosyl-1H-imidazole-4-carboxamide
CAS:Fórmula:C9H14N4O5Pureza:95%Forma y color:SolidPeso molecular:258.2313
