CAS 2627-69-2

AICAr

Descripción:

AICAr, o 5-aminoimidazol-4-carboxamida ribonucleótido, es un compuesto químico que desempeña un papel significativo en el metabolismo celular, particularmente en la vía de biosíntesis de purinas. Es un precursor de nucleótidos que está involucrado en la síntesis de adenosina monofosfato (AMP). AICAr es conocido por sus efectos potenciales en el metabolismo energético celular y ha sido estudiado por su papel en la activación de la quinasa de proteínas activada por AMP (AMPK), que es crucial para regular la homeostasis energética. El compuesto se investiga a menudo en el contexto de trastornos metabólicos, fisiología del ejercicio y aplicaciones terapéuticas potenciales para condiciones como la obesidad y la diabetes tipo 2. AICAr se caracteriza típicamente por su estructura molecular, que incluye un anillo de imidazol y un componente de ribonucleótido. Su número CAS, 2627-69-2, es un identificador único que facilita la identificación y el estudio de este compuesto en la literatura científica y bases de datos. En general, AICAr es una molécula significativa en bioquímica con implicaciones para la salud y el manejo de enfermedades.

Fórmula: C₉H₁₄N₄O₅

InChI: InChI=1S/C9H14N4O5/c10-7-4(8(11)17)12-2-13(7)9-6(16)5(15)3(1-14)18-9/h2-3,5-6,9,14-16H,1,10H2,(H2,11,17)/t3-,5-,6-,9-/m1/s1

Clave InChI: InChIKey=RTRQQBHATOEIAF-UUOKFMHZSA-N

SMILES: O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(N)=C(C(N)=O)N=C2

Sinónimos:

• 1-Ribosyl-4-carboxamido-5-aminoimidazole
• 1-β-<span class="text-smallcaps">D</span>-Ribofuranosyl-5-amino-4-imidazolecarboxamide
• 1H-Imidazole-4-carboxamide, 5-amino-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
• 5-Amino-1-beta-ribofuranosyl-imidazole-4-carboxamide
• 5-Amino-1-ribosyl-4-imidazolecarboxamide
• 5-Amino-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-imidazole-4-carboxamide
• 5-Amino-1-β-<span class="text-smallcaps">D</span>-ribofuranosylimidazole-4-carboxamide
• 5-Amino-1beta-D-ribofuranosylimidazole-4-carboxamide
• 5-Amino-4-imidazolecarboxamide ribofuranoside
• 5-Amino-4-imidazolecarboxamide riboside
• 5-Aminoimidazole-4-carboxamid-1-β-<span class="text-smallcaps">D</span>-ribofuranoside
• 5-Aminoimidazole-4-carboxamide 1-(β-<span class="text-smallcaps">D</span>-ribofuranoside)
• 5-Aminoimidazole-4-carboxamide ribonucleoside
• 5-Aminoimidazole-4-carboxamide riboside
• 5-Aminoimidazole-4-carboxamide-1-§-D-Ribofuranoside
• 5-amino-1-(beta-D-ribofuranosyl)-1H-imidazole-4-carboxamide
• AIC-Riboside
• AICA-riboside
• Acadra
• Aicar
• Arasine
• Gp 1-110
• Imidazole-4-carboxamide, 5-amino-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
• NSC 105823
• 5-Amino-1-β-D-ribofuranosyl-1H-imidazole-4-carboxamide
• 1H-Imidazole-4-carboxamide, 5-amino-1-β-D-ribofuranosyl-

5-Aminoimidazole-4-carboxamide 1-β-D-Ribofuranoside

CAS: 2627-69-2

Fórmula: C₉H₁₄N₄O₅

Pureza: >98.0%(HPLC)

Forma y color: White to Light yellow to Light red powder to crystal

Peso molecular: 258.23

Ref: 3B-A2528

5-Aminoimidazole-4-carboxamide 1-β-D-ribofuranoside, 98%

CAS: 2627-69-2

Activator of AMP-activated protein kinase (AMPK)

Fórmula: C₉H₁₄N₄O₅

Pureza: 98%

Peso molecular: 258.23

Ref: 02-J64720

AICAR

CAS: 2627-69-2

AICAR (Acadesine) is an AMPK activator, metabolic regulation, muscle function regulation, anti-cancer effect, neuroprotection. High-Quality, Low-Cost!

Fórmula: C₉H₁₄N₄O₅

Pureza: 98.00% - ≥95%

Forma y color: Solid

Peso molecular: 258.23

Ref: TM-T1477

AICAR

CAS: 2627-69-2

AICAR

Pureza: ≥95%

Peso molecular: 258.23g/mol

Ref: 54-BUP11706

5-Amino-1-(β-D-ribofuranosyl)-1H-imidazole-4-carboxamide

CAS: 2627-69-2

5-Amino-1-(β-D-ribofuranosyl)-1H-imidazole-4-carboxamide

Fórmula: C₉H₁₄N₄O₅

Pureza: 97%

Forma y color: off-white to white solid

Peso molecular: 258.23g/mol

Ref: 54-OR1170T

Acadesine

CAS: 2627-69-2

Fórmula: C₉H₁₄N₄O₅

Pureza: ≥ 98.0%

Forma y color: White to beige solid

Peso molecular: 258.23

Ref: 7W-GP6637

5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside

CAS: 2627-69-2

Applications AICAR is a nucleoside analogue that is able to enter nucleoside pools and is able to significantly increase levels of adenosine during periods of ATP breakdown. Adenosine-regulating agents (ARAs) have been recognized for therapeutic potential in myocardial ischemia. Cardioprotective.
References Mullane, K., et al.: Trends Cardiovasc Med., 3, 227 (1993), Browne, G.J., et al.: J. Biol. Chem., 279, 13, 12220 (2004)

Fórmula: C₉H₁₄N₄O₅

Forma y color: Neat

Peso molecular: 258.23

Ref: TR-A611700

5-Aminoimidazole-4-carboxamide-1-b-D-ribofuranose

CAS: 2627-69-2

Acadesine is a purine nucleoside analogue that inhibits the synthesis of ATP in cells. Acadesine blocks phosphorylation of adenosine monophosphate (AMP) to adenosine triphosphate (ATP) by inhibiting the activity of kinase-3, an enzyme involved in the production of ATP. Acadesine also inhibits the release of ATP from muscle cells into the blood stream and preferentially targets kidney cells, thereby reducing renal injury. Acadesine has been shown to be effective at reducing proteinuria and improving renal function in rats with acute kidney injury. Acadesine also has anti-inflammatory properties due to its ability to inhibit proteins that are involved in inflammation.

Fórmula: C₉H₁₄N₄O₅

Pureza: Min. 98 Area-%

Forma y color: Powder

Peso molecular: 258.23 g/mol

Ref: 3D-NA03552

AICA Riboside

CAS: 2627-69-2

M04018 - AICA Riboside

Fórmula: C₉H₁₄N₄O₅

Pureza: 98%

Forma y color: Solid

Peso molecular: 258.234

Ref: 10-M04018

5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside-15N4

Producto controlado

CAS: 2627-69-2

Applications A labelled nucleoside analogue that is able to enter nucleoside pools and is able to significantly increase levels of adenosine during periods of ATP breakdown. Adenosine-regulating agents (ARAs) have been recognized for therapeutic potential in myocardial ischemia. Cardioprotective.
References Mullane, K., et al.: Trends Cardiovasc Med., 3, 227 (1993), Browne, G.J., et al.: J. Biol. Chem., 279, 13, 12220 (2004)

Fórmula: C₉H₁₄₁₅N₄O₅

Forma y color: Neat

Peso molecular: 262.20

Ref: TR-A611703

5-Amino-1-β-D-ribofuranosyl-1H-imidazole-4-carboxamide

CAS: 2627-69-2

Fórmula: C₉H₁₄N₄O₅

Pureza: 95%

Forma y color: Solid

Peso molecular: 258.2313

Ref: IN-DA0034FR