CAS 26662-94-2

1-palmitoil-2-oleoil-sn-glicero-3-fosfoetanolamina

Descripción:

1-palmitoil-2-oleoil-sn-glicero-3-fosfoetanolamina, comúnmente conocido como POPE, es un fosfolípido que desempeña un papel crucial en las membranas celulares, particularmente en la formación de bicapas lipídicas. Se caracteriza por su naturaleza anfifílica, poseyendo regiones tanto hidrofílicas (el grupo cabeza de fosfoetanolamina) como hidrofóbicas (las colas de ácidos grasos), lo que facilita su integración en las membranas lipídicas. La estructura incluye una cadena de palmitoil saturada y una cadena de oleoil insaturada, contribuyendo a su fluidez y estabilidad en entornos de membrana. POPE se utiliza a menudo en estudios biofísicos y en la formulación de liposomas para la entrega de fármacos debido a su biocompatibilidad y capacidad para formar vesículas estables. Además, está involucrado en varios procesos biológicos, incluyendo la fusión de membranas y las vías de señalización. Su número CAS, 26662-94-2, es un identificador único que ayuda en la catalogación y referencia de esta sustancia química específica en la literatura científica y bases de datos.

Fórmula: C₃₉H₇₆NO₈P

InChI: InChI=1S/C39H76NO8P/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-39(42)48-37(36-47-49(43,44)46-34-33-40)35-45-38(41)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2/h17-18,37H,3-16,19-36,40H2,1-2H3,(H,43,44)/b18-17-/t37-/m1/s1

Clave InChI: InChIKey=FHQVHHIBKUMWTI-OTMQOFQLSA-N

SMILES: [C@@H](OC(CCCCCCC/C=C\CCCCCCCC)=O)(COC(CCCCCCCCCCCCCCC)=O)COP(OCCN)(=O)O

Sinónimos:

• (R)-1-((((2-Aminoethoxy)hydroxyphosphinyl)oxy)methyl)-2-((1-oxohexadecyl)oxy)ethyl oleate
• 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine
• 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphorylethanolamine
• 1-Palmitoyl-2-oleoyl-sn-glyceryl-3-phosphorylethanolamine
• 1-Palmitoyl-2-oleoylphosphatidylethanolamine
• 2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphatidylethanolamine
• 9-Octadecenoic acid (9Z)-, (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-2-[(1-oxohexadecyl)oxy]ethyl ester
• 9-Octadecenoic acid (Z)-, 1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-2-[(1-oxohexadecyl)oxy]ethyl ester, (R)-
• <span class="text-smallcaps">L</span>-α-1-Palmitoyl-2-oleoylglycerophosphoethanolamine
• Ethanol, 2-amino-, dihydrogen phosphate (ester) monoester with 1-palmito-2-olein, <span class="text-smallcaps">L</span>-
• Olein, 1-palmito-2-, dihydrogen phosphate mono(2-aminoethyl) ester, <span class="text-smallcaps">L</span>-
• Palmitin, 2-oleo-1-, dihydrogen phosphate mono(2-aminoethyl) ester, <span class="text-smallcaps">L</span>-
• Pe(16:0/18:1(9Z))
• Phosphatidyl-β-oleoyl-γ-palmitoyl ethanolamine
• Phosphatidylethanolamine (16:0/18:1)
• Olein, 1-palmito-2-, dihydrogen phosphate mono(2-aminoethyl) ester, L-
• Palmitin, 2-oleo-1-, dihydrogen phosphate mono(2-aminoethyl) ester, L-

POPE

CAS: 26662-94-2

POPE(1-Palmitoyl-2-oleoyl-sn-glycero-3-PE) is a compound found in Escherichia coli, part of the cell membrane, and can be used to study changes in cell membrane permeability.

Fórmula: C₃₉H₇₆NO₈P

Pureza: 97% - 98.02%

Forma y color: Solid

Peso molecular: 718

Ref: TM-TF0083

1-HEXADECANOYL-2-[CIS-9-OCTADECENOYL]-SN-GLYCERO-3-PHOSPHOETHANOLAMINE

CAS: 26662-94-2

Fórmula: C₃₉H₇₆NO₈P

Pureza: 97%

Forma y color: Solid

Peso molecular: 717.9964

Ref: IN-DA00BG77

2-Oleoyl-1-Palmitoyl-sn-Glycero-3-Phosphoethanolamine

CAS: 26662-94-2

2-Oleoyl-1-Palmitoyl-sn-Glycero-3-Phosphoethanolamine

Pureza: 97%

Peso molecular: 718.00g/mol

Ref: 54-OR1010577

POPE

CAS: 26662-94-2

POPE

Pureza: ≥95%

Peso molecular: 718g/mol

Ref: 54-BUP11134

1-Palmitoyl-2-Oleoyl-sn-Glycero-3-Phosphatidylethanolamine

CAS: 26662-94-2

Fórmula: C39H76NO8P

Pureza: >98%

Forma y color: Solid

Peso molecular: 718

Ref: 48-37-1828

1-Palmitoyl-2-Oleoyl-sn-Glycero-3-Phosphoethanolamine

CAS: 26662-94-2

Fórmula: C₃₉H₇₆NO₈P

Peso molecular: 718.01

Ref: 4Z-P-312001

POPE

Producto controlado

CAS: 26662-94-2

Stability Light Sensitive, Moisture Sensitive
Applications POPE is a component of E. Coli bacteria cell membrane.
References Tu, Y., et al.: Nature Nanotechnology, 8, 594 (2013).

Fórmula: C₃₉H₇₆NO₈P

Forma y color: Neat

Peso molecular: 718.0

Ref: TR-P689510

1-Palmitoyl-2-Oleoyl-sn-Glycero-3-Phosphatidylethanolamine

CAS: 26662-94-2

1-Palmitoyl-2-Oleoyl-sn-Glycero-3-Phosphatidylethanolamine is a broad spectrum antimicrobial that has been shown to have binding properties to peptides. This compound can be used as a potential antimicrobial for the treatment of bacterial infections and gramicidin, an antibiotic that is active against bacteria. It has also been shown to permeabilize cell membranes, which may lead to its function as an antimicrobial agent. 1-Palmitoyl-2-Oleoyl-sn-Glycero-3-Phosphatidylethanolamine is water soluble and has been shown to have conformational properties. These conformational properties are responsible for its binding activity with peptides. 1POGPE is stable in both calorimetric assays and bilayers, which allows it to maintain its structure when interacting with other compounds. 1POGPE also has a high affinity for

Fórmula: C₃₉H₇₆NO₈P

Pureza: Min. 95%

Peso molecular: 718 g/mol

Ref: 3D-BBA66294