CAS 27409-30-9

Picroside I

Descripción:

Picroside I es un compuesto glucósido derivado principalmente de las raíces de la planta Picrorhiza kurroa, conocida por sus propiedades medicinales en la medicina tradicional. Se caracteriza por su sabor amargo y a menudo se estudia por sus posibles efectos farmacológicos, incluyendo actividades hepatoprotectoras, antiinflamatorias y antioxidantes. La estructura química de Picroside I consiste en un moiety de glucosa unido a un aglicona fenólica, lo que contribuye a su actividad biológica. Es soluble en agua y solventes orgánicos, lo que lo hace versátil para diversas aplicaciones en formulaciones herbales e investigación. Además, se ha investigado el papel de Picroside I en la mejora de la función hepática y su posible uso en el tratamiento de trastornos hepáticos. Su perfil de seguridad y eficacia son temas de investigación en curso, enfatizando la importancia de comprender sus mecanismos de acción y potencial terapéutico. En general, Picroside I representa un compuesto significativo en el campo de los productos naturales y la farmacognosia.

Fórmula: C₂₄H₂₈O₁₁

InChI: InChI=1S/C24H28O11/c25-11-24-16-13(17(27)21(24)35-24)8-9-31-22(16)34-23-20(30)19(29)18(28)14(33-23)10-32-15(26)7-6-12-4-2-1-3-5-12/h1-9,13-14,16-23,25,27-30H,10-11H2/b7-6+/t13-,14-,16-,17+,18-,19+,20-,21+,22+,23+,24-/m1/s1

Clave InChI: InChIKey=XZGPUOQGERGURE-LUVHZPKESA-N

SMILES: C(O)[C@@]12[C@@](O1)([C@@H](O)[C@]3([C@@]2([C@H](O[C@@H]4O[C@H](COC(/C=C/C5=CC=CC=C5)=O)[C@@H](O)[C@H](O)[C@H]4O)OC=C3)[H])[H])[H]

Sinónimos:

• (1aS,1bS,2S,5aR,6S,6aS)-6-hydroxy-1a-(hydroxymethyl)-1a,1b,2,5a,6,6a-hexahydrooxireno[4,5]cyclopenta[1,2-c]pyran-2-yl 6-O-[(2E)-3-phenylprop-2-enoyl]-beta-D-glucopyranoside
• 6'-Cinnamoylcatalpol
• Amphicoside I
• Picroside I
• beta-D-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno(4,5)cyclopenta(1,2-c)pyran-2-yl, 6-(3-phenyl-2-propenoate), (1aS-(1aalpha,1bbeta,2beta(E),5abeta,6beta,6aalpha))-
• β-<span class="text-smallcaps">D</span>-Glucopyranoside, (1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl, 6-[(2E)-3-phenyl-2-propenoate]
• β-<span class="text-smallcaps">D</span>-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl, 6-(3-phenyl-2-propenoate), [1aS-[1aα,1bβ,2β(E),5aβ,6β,6aα]]-
• β-d-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl, 6-(3-phenyl-2-propenoate), [1aS-[1aα,1bβ,2β(E),5aβ,6β,6aα]]-
• β-D-Glucopyranoside, (1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl, 6-[(2E)-3-phenyl-2-propenoate]

Picroside I

CAS: 27409-30-9

Other glycosides, natural or reproduced by synthesis, and their salts, ethers, esters and other derivatives

Fórmula: C₂₄H₂₈O₁₁

Forma y color: White Powder

Peso molecular: 492.16316

Ref: 45-1538312

Picroside I

CAS: 27409-30-9

Fórmula: C₂₄H₂₈O₁₁

Pureza: 98%

Peso molecular: 492.4725

Ref: IN-DA00BBRS

Picroside I

CAS: 27409-30-9

Picroside I

Pureza: ≥98%

Peso molecular: 492.47g/mol

Ref: 54-BUP00055

Picroside I

CAS: 27409-30-9

Picroside I

Pureza: 98%

Peso molecular: 492.47g/mol

Ref: 54-OR1023026

Picroside 1

CAS: 27409-30-9

Fórmula: C₂₄H₂₈O₁₁

Peso molecular: 492.47

Ref: 7W-GC1565

Picroside I

CAS: 27409-30-9

Fórmula: C₂₄H₂₈O₁₁

Pureza: >95.0%(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 492.48

Ref: 3B-P2593

Picroside I

CAS: 27409-30-9

Picroside I is a hepatoprotective agent which is reported to be antimicrobial and used against hepatitis B. It has antioxidant, and anti-inflammatory activities, it may be the valuable anti-invasive drug candidates for cancer therapy by suppressing Collagenases and Gelatinases. Picroside I can enhance basic fibroblast growth factor(bFGF)-, staurosporine- or dbc-mitogen-activated protein (MAP)-induced neurite outgrowth from PC12D cells.

Fórmula: C₂₄H₂₈O₁₁

Pureza: 95%~99%

Peso molecular: 492.477

Ref: BP-BP1099

Picroside I

CAS: 27409-30-9

Picroside I (6'-Cinnamoylcatalpol), a hepatoprotective agent, is reported to be antimicrobial and used against hepatitis B.

Fórmula: C₂₄H₂₈O₁₁

Pureza: 99.70%

Forma y color: Solid

Peso molecular: 492.47

Ref: TM-T2787

Picroside i

CAS: 27409-30-9

Natural glycoside

Fórmula: C₂₄H₂₈O₁₁

Pureza: ≥ 90.0 % (HPLC)

Forma y color: Powder

Peso molecular: 492.48

Ref: 5G-89758

Picroside I

CAS: 27409-30-9

Picroside I is a naturally occurring iridoid glycoside, which is extracted from the plant Picrorhiza kurroa, commonly found in the Himalayan region. This compound acts primarily through its hepatoprotective and antioxidant properties, intervening in cellular pathways to reduce oxidative stress and inhibit inflammatory mediators. It effectively modulates liver enzymes and stabilizes cell membranes, thus supporting liver health.

Fórmula: C₂₄H₂₈O₁₁

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 492.48 g/mol

Ref: 3D-MP10467