CAS 27469-60-9

1-Bis(4-fluorofenil)metil piperazina

Descripción:

1-Bis(4-fluorofenil)metil piperazina, con el número CAS 27469-60-9, es un compuesto químico caracterizado por su núcleo de piperazina, que es una amina heterocíclica de seis miembros. Este compuesto presenta dos grupos para-fluorofenilo unidos a un anillo de piperazina central, lo que contribuye a sus propiedades únicas. Típicamente es un sólido a temperatura ambiente y exhibe una solubilidad moderada en disolventes orgánicos, que se ve influenciada por la presencia de los átomos de flúor que mejoran su lipofilia. Los sustituyentes de flúor también pueden afectar las propiedades electrónicas del compuesto, influyendo potencialmente en su reactividad e interacción con objetivos biológicos. 1-Bis(4-fluorofenil)metil piperazina puede ser de interés en la química medicinal, particularmente en el desarrollo de fármacos, debido a sus características estructurales que pueden modular la actividad biológica. Además, su síntesis y caracterización implican técnicas estándar de química orgánica, y puede ser estudiado por sus posibles aplicaciones en diversos campos, incluyendo el diseño de fármacos y la ciencia de materiales.

Fórmula: C₁₇H₁₈F₂N₂

InChI: InChI=1/C17H18F2N2/c18-15-5-1-13(2-6-15)17(21-11-9-20-10-12-21)14-3-7-16(19)8-4-14/h1-8,17,20H,9-12H2/p+2

Clave InChI: InChIKey=TTXIFFYPVGWLSE-UHFFFAOYSA-N

SMILES: C(C1=CC=C(F)C=C1)(C2=CC=C(F)C=C2)N3CCNCC3

Sinónimos:

• 1-(4,4'-Difluorobenzhydryl)Piperazine
• 1-(Di-p-fluorobenzhydryl)piperazine
• 1-[Bis(4-Fluorophenyl)Methyl]Piperazinediium
• 4,4'-Difluorobenzhydrylpiperazine
• 4-[Bis(4-fluorophenyl)methyl]piperazine
• Di(4-fluorophenyl)methyl piperazine
• N-(4,4-Difluorobenzhydryl)piperazine
• N-(Bis(4-fluorophenyl)methyl)piperazine
• Piperazine, 1-[bis(4-fluorophenyl)methyl]-
• Piperazine, 1-[bis(p-fluorophenyl)methyl]-
• R 19352
• T 841
• 1-[Bis(4-fluorophenyl)methyl]piperazine
• 1-[Bis(4-fluorophenyl)methyl]piperazine
• 1-(bis(4-fluorophenyl)methyl) piperazine
• 1-(4,4'-Diflurobenzhydryl)piperazine
• 1-(4,4'-DIFLUORODIPHENYLMETHYL)PIPERAZINE
• 1-(4,4'-Difluorobenzhydryl)piperazine 97%
• 1-[BIS(4-FLUOROPHENYL)METHYL]PIPERAZINE HYDROGEN CHLORIDE
• N-(4,4"-DIFLUOROBENZYLHYDRYL) PIPERAZINE
• 1-BIS (P-FLUOROPHENYL) METHYL PIPERAZINE
• 4,4-Difluorobenzhydrolpiperazine
• 1-[BIS(4-FLUOROPHENZYL)METHYL]PIPERAZINE
• 1-BIS(4-FLUOROPHENYL)METHYL PIPERAZINE 97%
• 1-(4,4'-Difluorobenzhydryl)piperazine97%
• TIMTEC-BB SBB002996
• 1-[DI(4-FLUOROPHENYL)METHYL]PIPERAZINE
• 1-[Bis(4-Fluorophenyl)methyl]p
• 4,4'-DIFLUOROBENZHYDRYL PIPERAZINE

1-[Bis(4-fluorophenyl)methyl]piperazine

CAS: 27469-60-9

Fórmula: C₁₇H₁₈F₂N₂

Pureza: >97.0%(GC)

Forma y color: White to Light yellow powder to crystal

Peso molecular: 288.34

Ref: 3B-B2764

1-Bis(4-fluorophenyl)methyl piperazine

CAS: 27469-60-9

Fórmula: C₁₇H₁₈F₂N₂

Pureza: 98%

Forma y color: Solid

Peso molecular: 288.3350

Ref: IN-DA003KF5

Flunarizine EP Impurity A

CAS: 27469-60-9

Fórmula: C₁₇H₁₈F₂N₂

Forma y color: White To Off-White Solid

Peso molecular: 288.34

Ref: 4Z-F-084009

1-[Bis(4-fluorophenyl)methyl]piperazine

CAS: 27469-60-9

1-[Bis(4-fluorophenyl)methyl]piperazine

Fórmula: C₁₇H₁₈F₂N₂

Pureza: 98%

Forma y color: white to off-white powder

Peso molecular: 288.34g/mol

Ref: 54-PC5636

Flunarizine EP Impurity A

Producto controlado

CAS: 27469-60-9

Fórmula: C₁₇H₁₈F₂N₂

Forma y color: Neat

Peso molecular: 288.34

Ref: 86-MM0175.04

1-Bis(4-fluorophenyl)methyl Piperazine

Producto controlado

CAS: 27469-60-9

Impurity Flumazenil EP Impurity A
Stability Hygroscopic
Applications 1-Bis(4-fluorophenyl)methyl Piperazine (Flumazenil EP Impurity A) is a chemical reagent used in the synthesis of novel tubulin polymerization inhibitors. Also used in the synthesis of novel benzhydrylpiperazine carboxamide derivatives. Impurity of F455200
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Yin, Y. et al.: Bioorg. Med. Chem., 22, 2409 (2014); Gurdal, E. et al.: J. Enz. Inhib. Med. Chem., 29, 205 (2014);

Fórmula: C₁₇H₁₈F₂N₂

Forma y color: White To Light Yellow

Peso molecular: 288.34

Ref: TR-B434875

1-[Bis-(4-fluorophenyl)methyl]piperazine

CAS: 27469-60-9

Pureza: 97.0%

Forma y color: Solid

Peso molecular: 288.3420104980469

Ref: 10-F019234

1-Bis(4-fluorophenyl)methyl Piperazine-d8

Producto controlado

CAS: 27469-60-9

Applications 1-Bis(4-fluorophenyl)methyl Piperzaine-d8 is a labelled analogue of 1-Bis(4-fluorophenyl)methyl Piperzaine (B434875), which is a chemical reagent used in the synthesis of novel tubulin polymerization inhibitors. Also used in the synthesis of novel benzhydrylpiperazine carboxamide derivatives. Impurity of F455200. It is also an intermediate in synthesizing Flunarizine-d8 Dihydrochloride (F455202), which is a calcium channel blocker; fluorinated derivative of Cinnarizine. Vasodilator (cerebral and peripheral).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Yin, Y. et al.: Bioorg. Med. Chem., 22, 2409 (2014); Gurdal, E. et al.: J. Enz. Inhib. Med. Chem., 29, 205 (2014); Desmedt, L.K., et al.: Arzneim.-Forsch., 25, 1408 (1975); Godfraind, T., et al.: Eur. J. Pharmacol., 53, 273 (1979); Nihard, P., et al.: Angiology, 33, 37 (1982); Holmes, B., et al.: Drugs, 27, 6 (1984);

Fórmula: C₁₇H₁₀D₈F₂N₂

Forma y color: Neat

Peso molecular: 296.38

Ref: TR-B434877

Flunarizine EP Impurity A

CAS: 27469-60-9

Fórmula: C₁₇H₁₈F₂N₂

Peso molecular: 288.34

Ref: ST-EA-CP-F140003

1-(4,4'-Difluorobenzhydry)piperazine

CAS: 27469-60-9

1-(4,4'-Difluorobenzhydry)piperazine (1-DFBP) is a potential antitumor agent that has been shown to inhibit the growth of leukemia cells. It may be an inhibitor of apoptotic cell death, as it has been shown to induce hydrogen bond formation with coumarin derivatives. 1-DFBP has also been shown to have inhibitory activities against leukemia HL-60 cells, and is a competitive inhibitor of cinnarizine. The catalytic mechanism for 1-DFBP is not known, although kinetic data suggest that it involves hydrogen bonding and/or pi stacking interactions.

Fórmula: C₁₇H₁₈F₂N₂

Pureza: Min. 95%

Peso molecular: 288.34 g/mol

Ref: 3D-FD55069