CAS 27548-93-2
:Baccatina III
Descripción:
Baccatina III es un compuesto químico que ocurre de forma natural, clasificado como un diterpeno, específicamente un taxano, y se deriva principalmente del tejo del Pacífico (Taxus brevifolia). Es conocido por su complejidad estructural, que presenta un núcleo bicíclico único característico de los taxanos. Baccatina III sirve como un precursor crucial en la síntesis del fármaco anticancerígeno paclitaxel (Taxol), que se utiliza en el tratamiento de varios tipos de cáncer, incluidos el cáncer de ovario y de mama. El compuesto exhibe una actividad biológica significativa, particularmente en su capacidad para estabilizar microtúbulos e inhibir la división celular, lo que lo convierte en un valioso objeto de investigación en química medicinal. Baccatina III se caracteriza típicamente por su fórmula molecular, que refleja su composición de átomos de carbono, hidrógeno y oxígeno. Sus propiedades de solubilidad y estabilidad bajo diversas condiciones también son de interés en aplicaciones farmacéuticas. En general, Baccatina III desempeña un papel vital en el desarrollo de agentes terapéuticos y continúa siendo estudiado por su potencial en el tratamiento del cáncer y otras aplicaciones médicas.
Fórmula:C31H38O11
InChI:InChI=1S/C31H38O11/c1-15-19(34)13-31(38)26(41-27(37)18-10-8-7-9-11-18)24-29(6,20(35)12-21-30(24,14-39-21)42-17(3)33)25(36)23(40-16(2)32)22(15)28(31,4)5/h7-11,19-21,23-24,26,34-35,38H,12-14H2,1-6H3/t19-,20-,21+,23+,24-,26-,29+,30-,31+/m0/s1
Clave InChI:InChIKey=OVMSOCFBDVBLFW-VHLOTGQHSA-N
SMILES:O(C(C)=O)[C@]12[C@]3([C@H](OC(=O)C4=CC=CC=C4)[C@@]5(O)C(C)(C)C([C@@H](OC(C)=O)C(=O)[C@]3(C)[C@@H](O)C[C@]1(OC2)[H])=C(C)[C@@H](O)C5)[H]
Sinónimos:- (1Beta,2Alpha,5Beta,7Beta,10Alpha,13Alpha)-4,10-Bis(Acetyloxy)-1,7,13-Trihydroxy-9-Oxo-5,20-Epoxytax-11-En-2-Yl Benzoate
- (2Alpha,3Beta,5Beta,7Beta,10Beta,13Alpha)-4,10-Bis(Acetyloxy)-1,7,13-Trihydroxy-9-Oxo-5,20-Epoxytax-11-En-2-Yl Benzoate
- (2Alpha,3Xi,5Beta,7Beta,10Beta,13Alpha)-4,10-Bis(Acetyloxy)-1,7,13-Trihydroxy-9-Oxo-5,20-Epoxytax-11-En-2-Yl Benzoatato
- (2Alpha,5Beta,7Beta,10Beta,13Alpha)-4,10-Bis(Acetyloxy)-1,7,13-Trihydroxy-9-Oxo-5,20-Epoxytax-11-En-2-Yl Benzoate
- (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,9,11-trihydroxy-4a,8,13,13-tetramethyl-7,11-methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one
- 7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one, 6,12b-bis(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,9,11-trihydroxy-4a,8,13,13-tetramethyl-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-
- 7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one, 6,12b-bis(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,9,11-trihydroxy-4a,8,13,13-tetramethyl-, [2aR-(2aα,4β,4aβ,6β,9α,11α,12α,12aα,12bα)]-
- Baccatin III
- NSC 330753
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Encontrado 13 productos.
Baccatin III ((2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12-(Benzoyloxy)-4,9,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-3,4,4a,5,6,9,10,11,12,12a-decahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxete-6,12b(2aH)-diyl diacetate)
CAS:Aromatic heterocyclic compounds with oxygen hetero-atom(s) only, nesoiFórmula:C31H38O11Forma y color:White SolidPeso molecular:586.24141Baccatin III
CAS:<p>Baccatin III: polycyclic diterpene for semi-synthetic paclitaxel, with immunomodulatory and anticancer properties.</p>Fórmula:C31H38O11Pureza:98.45%Forma y color:White To Off-White PowderPeso molecular:586.63Baccatin III
CAS:Fórmula:C31H38O11Pureza:≥ 98.0%Forma y color:White to off-white powderPeso molecular:586.63Paclitaxel EP Impurity N (Baccatin III)
CAS:Fórmula:C31H38O11Forma y color:White To Off-White SolidPeso molecular:586.63Baccatin III
CAS:Baccatin III, which is the precursor for the semisynthesis of paclitaxel,exerts anti-tumor immunomodulatory activity in very low doses (0.05-0.5mg/kg),it reduces tumor progression by inhibiting the accumulation and suppressive function of MDSCs. Baccatin III also exerts immunomodulatory activities in vivo as well as in vitro on the MHC-restricted antigen presentation.Fórmula:C31H38O11Pureza:95%~99%Peso molecular:586.634Paclitaxel EP Impurity N
CAS:Producto controladoFórmula:C31H38O11Forma y color:NeatPeso molecular:586.63Baccatin iii
CAS:Oxygen-heterocyclic compoundFórmula:C31H38O11Pureza:≥ 95.0 % (HPLC)Forma y color:PowderPeso molecular:586.64Baccatin III
CAS:Producto controlado<p>Impurity Paclitaxel - Impurity N<br>Applications A precursor to Paclitaxel, a neoplasm inhibitor to ovarian and breast cancers found in Taxus species. Paclitaxel - Impurity N.<br>References Katkovcinova, Z., et al.: J. Biosci., 63, 721 (2008), Tian, J., et al.: J. Pharm. Sci., 97, 3100 (2008), Miao, Z., et al.: App. Biochem. Microbiol., 45, 81 (2009),<br></p>Fórmula:C31H38O11Forma y color:NeatPeso molecular:586.63Baccatin III
CAS:<p>Baccatin III is a naturally occurring diterpenoid compound, which is sourced from the needles of the European yew tree, *Taxus baccata*. This plant-based compound serves as a crucial precursor in the biosynthesis and semi-synthesis of paclitaxel, a chemotherapeutic agent widely used in cancer treatment. The mode of action of baccatin III involves its transformation into more active drug forms, such as paclitaxel and docetaxel, both of which function by stabilizing microtubules and thus inhibiting cell division.</p>Fórmula:C31H38O11Pureza:Min. 97.5 Area-%Forma y color:White PowderPeso molecular:586.63 g/mol7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one, 6,12b-bis(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,9,11-trihydroxy-4a,8,13,13-tetramethyl-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-
CAS:Fórmula:C31H38O11Forma y color:SolidPeso molecular:586.6268
![7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one, 6,12b-bis(acetyloxy)-12-(benzoyloxy)-1,2a,3,4…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA002U1C.jpg&w=3840&q=75)
