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CAS 2757498-74-9

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  • ER covalent antagonist-1
    Targetmol
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    ER covalent antagonist-1

    CAS:
    <p>ER covalent antagonist-1 (Compound 39D) acts as an antagonist of the estrogen receptor α (ERα). This compound inhibits the proliferation of ERα-positive MCF-7 cells with an IC50 of 0.98 μM, induces cell cycle arrest at the G0/G1 phase, and triggers apoptosis. Additionally, ER covalent antagonist-1 demonstrates antitumor activity in mouse models.</p>
    Fórmula:C33H32N2O5S
    Forma y color:Solid
    Peso molecular:568.683

    Ref: TM-T204764