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CAS 2760515-88-4

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  • mG2N001
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    mG2N001

    CAS:
    mG2N001, a negative allosteric modulator (NAM) of the metabotropic glutamate receptor mGluR2, has an IC50 of 93 nM and binds to mGluR2 as an antagonist with a Ki of 63 nM. This compound is microparticle- and plasma-stable, and its radioisotope [11C] mG2N001 can be utilized in PET imaging. [11C] mG2N001 exhibits good brain heterogeneity and penetration, selectively accumulating in mGluR2-rich regions to produce high-contrast brain images [1].
    Fórmula:C18H19FN2O3
    Forma y color:Solid
    Peso molecular:330.35

    Ref: TM-T86893