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CAS 2782022-40-4

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  • LD4172
    Targetmol
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    LD4172

    CAS:
    <p>LD4172 is a PROTAC degrader capable of degrading RIP kinase (RIPK1) with a DC50 in the nanomolar range. When used in combination with TNF-α, LD4172 can induce apoptosis in B16F10 cells. In mouse models, it demonstrates antitumor activity. (Pink: ligand for target protein; Black: linker; Blue: ligand for E3 ligase VHL)</p>
    Fórmula:C61H75F3N10O7S
    Forma y color:Solid
    Peso molecular:1149.37

    Ref: TM-T204416