CAS 2841750-32-9

6-Chloro-1,5-dihydro-7-(4-methylphenyl)imidazo[2,1-b]quinazolin-2(3H)-one

Fórmula: C₁₇H₁₄ClN₃O

Sinónimos:

• 6-Chloro-1,5-dihydro-7-(4-methylphenyl)imidazo[2,1-b]quinazolin-2(3H)-one
• Antitumor agent-100

Antitumor agent-100

CAS: 2841750-32-9

Antitumor Agent-100 (compound A6) is a molecular gel and apoptosis inducer targeting PDE3A-SLFN12 with an IC50 of 0.3 μM, demonstrating potent antitumor activity. This orally available agent binds to the PDE3A enzyme pocket, recruiting and stabilizing SLFN12 which disrupts protein translation and induces apoptosis [1].

Fórmula: C₁₇H₁₄ClN₃O

Forma y color: Solid

Peso molecular: 311.77

Ref: TM-T85701