CAS 28541-83-5

4-Metilumbeliferil α-D-manopiranósido

Descripción:

4-Metilumbeliferil α-D-manopiranósido (CAS 28541-83-5) es un glucósido sintético comúnmente utilizado como sustrato en ensayos enzimáticos, particularmente para la detección de la actividad de α-manosidasa. Este compuesto presenta una parte de 4-metilumbeliferona, que es un marcador fluorescente, unida a una unidad de α-D-mannopiranósido. Su estructura permite la liberación de 4-metilumbeliferona tras la hidrólisis por enzimas específicas, resultando en una fluorescencia medible que puede ser cuantificada. La sustancia es típicamente un polvo blanco a blanco sucio y es soluble en agua y disolventes orgánicos, lo que la hace versátil para aplicaciones de laboratorio. Es estable en condiciones normales, pero debe ser almacenada en un lugar fresco y seco para mantener su integridad. La fluorescencia emitida tras la escisión enzimática la convierte en una herramienta valiosa en la investigación bioquímica, particularmente en estudios que involucran el metabolismo de carbohidratos y la cinética enzimática. Se deben consultar las hojas de datos de seguridad para las pautas de manejo y eliminación, como con cualquier reactivo químico.

Fórmula: C₁₆H₁₈O₈

InChI: InChI=1S/C16H18O8/c1-7-4-12(18)23-10-5-8(2-3-9(7)10)22-16-15(21)14(20)13(19)11(6-17)24-16/h2-5,11,13-17,19-21H,6H2,1H3/t11-,13-,14+,15+,16+/m1/s1

Clave InChI: InChIKey=YUDPTGPSBJVHCN-VMMWWAARSA-N

SMILES: CC=1C=2C(=CC(O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]3O)=CC2)OC(=O)C1

Sinónimos:

• 7-(α-D-Mannopyranosyloxy)-4-methyl-2H-1-benzopyran-2-one
• 4-Methylumbelliferyl α-D-mannoside
• 2H-1-Benzopyran-2-one, 7-(α-D-mannopyranosyloxy)-4-methyl-
• 4-Methylumbelliferyl α-D-mannopyranoside
• Mannopyranoside, 4-methyl-2-oxo-2H-1-benzopyran-7-yl, α-D-

2H-1-Benzopyran-2-one, 7-(α-D-mannopyranosyloxy)-4-methyl-

CAS: 28541-83-5

Fórmula: C₁₆H₁₈O₈

Pureza: 97%

Forma y color: Solid

Peso molecular: 338.3093

Ref: IN-DA002VOE

4-Methylumbelliferyl a-D-mannopyranoside

CAS: 28541-83-5

Fórmula: C₁₆H₁₈O₈

Peso molecular: 338.30

Ref: 7W-GC6981

4-Methylumbelliferyl α-D-Mannopyranoside

CAS: 28541-83-5

Fórmula: C₁₆H₁₈O₈

Pureza: >97.0%(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 338.31

Ref: 3B-M3023

4-Methylumbelliferyl-α-D-mannopyranoside

CAS: 28541-83-5

4-Methylumbelliferyl-α-D-mannopyranoside

Fórmula: C₁₆H₁₈O₈

Pureza: By hplc: >99% (Typical Value in Batch COA)

Forma y color: white crystalline powder

Peso molecular: 338.31g/mol

Ref: 54-BIM1100

4-Methylumbelliferyl a-D-Mannopyranoside

CAS: 28541-83-5

Stability Hygroscopic
Applications A substrate for mannosidase.

Fórmula: C₁₆H₁₈O₈

Forma y color: Neat

Peso molecular: 338.31

Ref: TR-M334745

4-Methylumbelliferyl a-D-mannopyranoside

CAS: 28541-83-5

4-Methylumbelliferyl alpha-D-mannopyranoside (4-MU-a-D-Man) is a fluorogenic substrate used in activity assays for alpha-mannosidase. When it is hydrolyzed by alpha-mannosidase, it produces a fluorescent compound, 4-methylumbelliferone (4-MU). 4-MU-a-D-Man is often used in medical research to monitor the activity of alpha-mannosidase, which is important in lysosomal storage diseases.  In addition, 4-Methylumbelliferyl alpha-D-mannopyranoside has been used to study the the activity of concanavalin A, a lectin that specifically binds to alpha-D-mannopyranosyl and alpha-D-glucopyranosyl residues on various glycoproteins. The use of this fluorogenic enzyme substrate permits study the degree of alpha-D-mannosidic linkage cleavage by the enzyme.

Fórmula: C₁₆H₁₈O₈

Pureza: Min. 98 Area-%

Forma y color: White Off-White Powder

Peso molecular: 338.31 g/mol

Ref: 3D-EM03179

4-Methylumbelliferyl-α-D-mannopyranoside

CAS: 28541-83-5

4-Methylumbelliferyl alpha-D-mannopyranoside (4-MU-a-D-Man) is a fluorogenic substrate used in activity assays for alpha-mannosidase. When it is hydrolyzed by alpha-mannosidase, it produces a fluorescent compound, 4-methylumbelliferone (4-MU). 4-MU-a-D-Man is often used in medical research to monitor the activity of alpha-mannosidase, which is important in lysosomal storage diseases.  In addition, 4-Methylumbelliferyl alpha-D-mannopyranoside has been used to study the the activity of concanavalin A, a lectin that specifically binds to alpha-D-mannopyranosyl and alpha-D-glucopyranosyl residues on various glycoproteins. The use of this fluorogenic enzyme substrate permits study the degree of alpha-D-mannosidic linkage cleavage by the enzyme.

Fórmula: C₁₆H₁₈O₈

Pureza: Min. 98 Area-%

Peso molecular: 338.32 g/mol

Ref: 3D-M-5730

GC-204

CAS: 28541-83-5

GC-204 is a selective inhibitor of carbonic anhydrase ix (caix)

Fórmula: C₁₆H₁₈O₈

Forma y color: Solid

Peso molecular: 338.31

Ref: TM-T71877