CAS 2858658-44-1

Methanone, [4-(5,5-dioxidodibenzo[b,e]thiepin-11(6H)-ylidene)-1-piperidinyl]-1H-pyrrolo[3,2-c]pyridin-7-yl-

Fórmula: C₂₇H₂₃N₃O₃S

Sinónimos:

• Methanone, [4-(5,5-dioxidodibenzo[b,e]thiepin-11(6H)-ylidene)-1-piperidinyl]-1H-pyrrolo[3,2-c]pyridin-7-yl-

NZ-804

CAS: 2858658-44-1

NZ-804 is an orally active inhibitor of the SARS-CoV-2 main protease (Mpro) with an IC50 of 8.9 nM. It inhibits replication of SARS-CoV-2 in HeLa-hACE2 cells, showing an EC50 of 14 nM. NZ-804 exhibits broad-spectrum antiviral activity against various CoVs and decreases viral replication in mice and hamster models.

Fórmula: C₂₇H₂₃N₃O₃S

Peso molecular: 469.56

Ref: TM-T203497