CAS 289042-10-0

Intermedios de Rosuvastatina ZD9

Descripción:

Intermedios de Rosuvastatina ZD9, con el número CAS 289042-10-0, es un compuesto químico que sirve como intermediario en la síntesis de rosuvastatina, un medicamento estatina de uso común para reducir los niveles de colesterol. Este compuesto típicamente exhibe características comunes a los intermediarios orgánicos, incluyendo una estructura molecular específica que facilita su papel en las reacciones químicas. Es probable que sea un sólido a temperatura ambiente, con solubilidad moderada en disolventes orgánicos, lo cual es típico para muchos intermediarios farmacéuticos. El compuesto puede poseer grupos funcionales que son reactivos, permitiéndole participar en transformaciones sintéticas adicionales. Las hojas de datos de seguridad indicarían precauciones de manejo, ya que los intermediarios pueden ser a menudo peligrosos. Además, su pureza y estabilidad son cruciales para la eficiencia de la síntesis del producto final. En general, Intermedios de Rosuvastatina ZD9 juega un papel vital en la industria farmacéutica, contribuyendo a la producción de terapias efectivas para reducir el colesterol.

Fórmula: C₂₈H₂₉FN₃O₃PS

InChI: InChI=1/C28H29FN3O3PS/c1-20(2)26-25(19-36(33,23-11-7-5-8-12-23)24-13-9-6-10-14-24)27(21-15-17-22(29)18-16-21)31-28(30-26)32(3)37(4,34)35/h5-18,20H,19H2,1-4H3

Clave InChI: InChIKey=CVRDGWDBQZPJJI-UHFFFAOYSA-N

SMILES: C(P(=O)(C1=CC=CC=C1)C2=CC=CC=C2)C=3C(=NC(N(S(C)(=O)=O)C)=NC3C(C)C)C4=CC=C(F)C=C4

Sinónimos:

• 4-(4-Fluorophenyl)-5-(diphenylphosphinyl)methyl-6-isopropyl-2-[(N-methyl-n-methylsulfonyl)amino]pyrimidine
• Methanesulfonamide, N-[5-[(diphenylphosphinyl)methyl]-4-(4-fluorophenyl)-6-(1-methylethyl)-2-pyrimidinyl]-N-methyl-
• N-[5-(Diphenyl-phosphinoylmethyl)-4-(4-fluoro-phenyl)-6-isopropyl-pyrimidin-2-yl]-N-methyl-methanesulfonamide
• N-[5-(Diphenylphosphinoylmethyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide
• N-[5-[(Diphenylphosphinyl)methyl]-4-(4-fluorophenyl)-6-(1-methylethyl)-2-pyrimidinyl]-N-methylmethanesulfonamide
• N-{5-[(diphenylphosphoryl)methyl]-4-(4-fluorophenyl)-6-(1-methylethyl)pyrimidin-2-yl}-N-methylmethanesulfonamide
• Z-8.1
• -4-(4-fluorophenyl)
• Diphenyl[4-(4-fluorophenyl)-6-isopropyl-2-[(2-n-Methyl-n-Methylsulfonyl)aMino]pyriMidine-5-yl-Methyl]phosphine oxide
• Rosuvastatin Intermediates ZD9
• N-(5-((Diphenylphosphoryl)methyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl)-N-methylmethan
• isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide(Z8.3)
• N-[5-(Diphenylphosphinoylmethyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfon
• Diphenyl[4-(4-Fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonyl)amino-pyrimidin-5-yl-methyl]phosph
• N-(5-((Diphenylphosphoryl)methyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesu
• N-(5-((Diphenylphosphoryl)
• Triphenyl[4-(4-fluorophenyl)-6-isopropyl-2-[(2-n-methyl-n-methylsulfonyl)amino]pyrimidine-5-yl-methyl]phosphine bromine
• N-(5-((Diphenylphosphoryl)Methyl)-4-(4-fluorophenyl)-6-isopropylpyriMidin-2-yl)-N-MethylMethanesulfonaMide
• -6-isopropylpyrimidin-2-yl)
• N-[5-(diphenylphosphorylmethyl)-4-(4-fluorophenyl)-6-propan-2-ylpyrimidin-2-yl]-N-methylmethanesulfonamide
• 4-(4-fluorophenyl)-6-isopropyl-2-[(n-methyl-n-methylsulfonyl)amino] pyriminl-5-yl- phosphine oxide
• Diphenyl [4-(4-fluorophenyl)- 6-isopropyl-2-[(n-Methyl- n-ethylsulfonyl)aMino] pyriMidine-5-yl- ethyl]phosphine
• Diphenyl[4-(4-Fluorophenyl)-6-isopropyl-2-(N-MethylMethylsulfonyl)aMino-pyriMidin-5-yl-Methyl]phosphine Oxide
• Z-8: DIPHENYL [4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-[(N-METHYL-N-METHYLSULFONYL) AMINO] PYRIMIDINE-5-YL-METHYL] PHOSPHINE OXIDE
• N-[5-(Diphenylphosphinoylmethyl)-4-(4-fluorophenyl)-6-
• Rosuvastatin InterMediate Z-8.1
• rosuvastatin intermediates Z-8.1

Methanesulfonamide, N-[5-[(diphenylphosphinyl)methyl]-4-(4-fluorophenyl)-6-(1-methylethyl)-2-pyrimidinyl]-N-methyl-

CAS: 289042-10-0

Fórmula: C₂₈H₂₉FN₃O₃PS

Pureza: 97%

Forma y color: Solid

Peso molecular: 537.5853

Ref: IN-DA002X0S

N-(5-((Diphenylphosphoryl)methyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide

CAS: 289042-10-0

N-(5-((Diphenylphosphoryl)methyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide

Pureza: 97%

Peso molecular: 537.6g/mol

Ref: 54-PC1004208

N-[5-[(Diphenylphosphinyl)methyl]-4-(4-fluorophenyl)-6-(1-methylethyl)-2-pyrimidinyl]-N-methylmethanesulfonamide

CAS: 289042-10-0

Forma y color: Neat

Ref: 86-MM0936.35

Rosuvastatin Impurity 133

CAS: 289042-10-0

Fórmula: C₂₈H₂₉FN₃O₃PS

Peso molecular: 537.59

Ref: 4Z-R-09184

Rosuvastatin Impurity 37

CAS: 289042-10-0

Fórmula: C₂₈H₂₉FN₃O₃PS

Peso molecular: 537.59

Ref: ST-EA-CP-R1105

Diphenyl[4-(4-Fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonyl)amino-pyrimidin-5-yl-methyl]phosphine Oxide

Producto controlado

CAS: 289042-10-0

Applications An intermediate in the production of Rosuvastatin (R700500) derivatives.
References Liu, Y. et al.: Guang. Huag., 39, 54 (2011);

Fórmula: C₂₈H₂₉FN₃O₃PS

Forma y color: Neat

Peso molecular: 537.59

Ref: TR-D491600