CAS 2921-57-5

Succinato de metilprednisolona

Descripción:

Succinato de metilprednisolona es un corticosteroide sintético con propiedades antiinflamatorias e inmunosupresoras, comúnmente utilizado en el tratamiento de diversas condiciones como alergias, trastornos autoinmunes y ciertos tipos de cáncer. Es un derivado de la metilprednisolona, que es una forma modificada de la hormona esteroide cortisol. La sustancia se caracteriza por su capacidad para inhibir la liberación de mediadores inflamatorios y modular las respuestas inmunitarias. Succinato de metilprednisolona se administra típicamente por inyección y es conocido por su rápido inicio de acción. Su estructura química incluye un éster succinato, que mejora su solubilidad y biodisponibilidad. El compuesto generalmente es bien tolerado, pero los efectos secundarios potenciales pueden incluir un mayor riesgo de infecciones, trastornos gastrointestinales y alteraciones en el metabolismo de la glucosa. Al igual que otros corticosteroides, el uso a largo plazo requiere un monitoreo cuidadoso debido a posibles efectos adversos en varios sistemas orgánicos. En general, Succinato de metilprednisolona es un agente terapéutico valioso en el manejo de condiciones inflamatorias y autoinmunes.

Fórmula: C₂₆H₃₄O₈

InChI: InChI=1S/C26H34O8/c1-14-10-16-17-7-9-26(33,20(29)13-34-22(32)5-4-21(30)31)25(17,3)12-19(28)23(16)24(2)8-6-15(27)11-18(14)24/h6,8,11,14,16-17,19,23,28,33H,4-5,7,9-10,12-13H2,1-3H3,(H,30,31)/t14-,16-,17-,19-,23+,24-,25-,26-/m0/s1

Clave InChI: InChIKey=IMBXEJJVJRTNOW-XYMSELFBSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C([C@@H](C)C3)=CC(=O)C=C4)([C@@H](O)C1)[H])[H])(CC[C@@]2(C(COC(CCC(O)=O)=O)=O)O)[H]

Sinónimos:

• (6α,11β)-21-(3-Carboxy-1-oxopropoxy)-11,17-dihydroxy-6-methylpregna-1,4-diene-3,20-dione
• 11Beta,17,21-Trihydroxy-6Alpha-Methylpregna-1,4-Diene-3,20-Dione 21-(Hydrogen Succinate)
• 4-{[(6Alpha,11Beta)-11,17-Dihydroxy-6-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl]Oxy}-4-Oxobutanoic Acid
• 6-Methylprednisolone hemisuccinate
• 6α-Methylprednisolone 21-succinate
• 6α-Methylprednisolone hemisuccinate
• Methylprednisolone 21-hemisuccinate
• Methylprednisolone succinate
• Pregna-1,4-diene-3,20-dione, 11β,17,21-trihydroxy-6α-methyl-, 21-(H succinate)
• Pregna-1,4-diene-3,20-dione, 11β,17,21-trihydroxy-6α-methyl-, 21-(hydrogen succinate)
• Pregna-1,4-diene-3,20-dione, 11β,17,21-trihydroxy-6α-methyl-, 21-succinate

Methylprednisolone Hydrogen Succinate

CAS: 2921-57-5

Forma y color: Neat

Ref: 61-FOR1515.00

METHYLPREDNISOLONE HYDROGEN SUCCINATE FOR PERFORMANCE TEST CRS

CAS: 2921-57-5

METHYLPREDNISOLONE HYDROGEN SUCCINATE FOR PERFORMANCE TEST CRS

Forma y color: Powder

Ref: 41-M1755220

METHYLPREDNISOLONE HYDROGEN SUCCINATE CRS

CAS: 2921-57-5

METHYLPREDNISOLONE HYDROGEN SUCCINATE CRS

Fórmula: C₂₆H₃₄O₈

Forma y color: Powder

Peso molecular: 474.5434

Ref: 41-M1755200

METHYLPREDNISOLONE HYDROGEN SUCCINATE FOR PEAK IDENTIFICATION CRS

CAS: 2921-57-5

METHYLPREDNISOLONE HYDROGEN SUCCINATE FOR PEAK IDENTIFICATION CRS

Fórmula: C₂₆H₃₄O₈

Forma y color: Powder

Peso molecular: 474.5434

Ref: 41-Y0001759

Methylprednisolone Hemisuccinate

CAS: 2921-57-5

Adrenal cortical hormones and their derivatives nesoi

Fórmula: C₂₆H₃₄O₈

Forma y color: White Off-White Powder

Peso molecular: 474.22537

Ref: 45-1437009

Methylprednisolone 21-Hemisuccinate (Methylprednisolone Hydrogen Succinate)

CAS: 2921-57-5

Fórmula: C₂₆H₃₄O₈

Forma y color: White To Off-White Solid

Peso molecular: 474.55

Ref: 4Z-P-11138

Methylprednisolone succinate

CAS: 2921-57-5

Methylprednisolone succinate

Pureza: ≥98%

Peso molecular: 474.54g/mol

Ref: 54-BUP11730

Methylprednisolone Hydrogen Succinate

Producto controlado

CAS: 2921-57-5

Fórmula: C₂₆H₃₄O₈

Forma y color: Neat

Peso molecular: 474.54

Ref: 86-MM1515.00

Methylprednisolone succinate

CAS: 2921-57-5

Methylprednisolone succinate (Methylprednisolone hemisuccinate) is a synthetic glucocorticoid and is widely used as an anti-inflammatory agent.

Fórmula: C₂₆H₃₄O₈

Pureza: 98.41% - 99.82%

Forma y color: White Or Almost-White Solid Powder

Peso molecular: 474.54

Ref: TM-T22367

Methylprednisolone Succinate RS

CAS: 2921-57-5

Forma y color: White Solid Crystalline Powder

Ref: 2K-1165000021

Methylprednisolone 21-Hemisuccinate

CAS: 2921-57-5

Fórmula: C₂₆H₃₄O₈

Peso molecular: 474.55

Ref: ST-EA-CP-M14014

6a-Methylprednisolone 21-Hemisuccinate

Producto controlado

CAS: 2921-57-5

Applications 6α-Methylprednisolone 21-Hemisuccinate is a derivative of methylprednisolone (M325934), a glucocorticoid and a anti-inflammatory drug used to treat central nervous system disorders such as multiple sclerosis. 6α-Methylprednisolone 21-Hemisuccinate was examined for potential therapeutic efficacy in a model of neuroinflammation in rats with acute autoimmune encephalomyelitis.
References Gaillard, P.J., et al.: J. Controlled. Release., 164, 364 (2012);

Fórmula: C₂₆H₃₄O₈

Forma y color: White To Off-White

Peso molecular: 474.54

Ref: TR-M331195

Methylprednisolone hemisuccinate

Producto controlado

CAS: 2921-57-5

Meghylprednisolone hemisuccinate is a nonsteroidal anti-inflammatory drug (NSAID) that belongs to the group of pharmacological agents. It is used for pain relief in cases of inflammatory bowel disease, and has been shown to be effective against human immunoglobulin A (IgA) nephropathy. Meghylprednisolone hemisuccinate inhibits prostaglandin synthesis by binding to the enzyme cyclooxygenase and blocking the conversion of arachidonic acid to prostaglandins. This drug also blocks the production of leukotrienes, which are mediators of inflammation and tissue injury. Meghylprednisolone hemisuccinate has been shown to be less toxic than methylprednisolone sodium succinate in rats when given at low doses orally, although it has not been studied in humans.

Fórmula: C₂₆H₃₄O₈

Pureza: Min. 95%

Peso molecular: 474.54 g/mol

Ref: 3D-FM39645