CAS 2930726-89-7

Selenocyanic acid, 3-[[3-[[3,5-bis(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-1-yl]carbonyl]-2-oxo-2H-1-benzopyran-7-yl]oxy]propyl ester

Fórmula: C₂₉H₂₁F₂N₃O₄Se

Sinónimos:

• Selenocyanic acid, 3-[[3-[[3,5-bis(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-1-yl]carbonyl]-2-oxo-2H-1-benzopyran-7-yl]oxy]propyl ester

EMT inhibitor-3

CAS: 2930726-89-7

EMT inhibitor-3 (compound 11i) is an epithelial-mesenchymal transition (EMT) inhibitor that effectively suppresses the proliferation, migration, and invasion of SK-N-SH neuroblastoma cells, with an IC50 value of 2.5 μM. It induces mitochondrial-mediated intrinsic apoptosis in tumor cells by enhancing the Bax/Bcl-2 protein expression ratio, promoting the release of cytochrome C from mitochondria, and activating caspase 9 and caspase 3. EMT inhibitor-3 is applicable for cancer research.

Fórmula: C₂₉H₂₁F₂N₃O₄Se

Forma y color: Solid

Peso molecular: 592.45

Ref: TM-T205130