CAS 29428-50-0

Acetato de metilo 1,2,3,4-tetrahidro-2,4-dioxo-1-β-D-ribofuranosil-5-pirimidina

Descripción:

Acetato de metilo 1,2,3,4-tetrahidro-2,4-dioxo-1-β-D-ribofuranosil-5-pirimidina, con el número CAS 29428-50-0, es un compuesto químico que presenta una estructura compleja caracterizada por un anillo de pirimidina y un moiety ribofuranosilo. Este compuesto es notable por su potencial actividad biológica, particularmente en el contexto de análogos de nucleósidos, que pueden influir en el metabolismo de ácidos nucleicos. La presencia de los grupos tetrahidro y dioxo contribuye a su reactividad y estabilidad bajo diversas condiciones. Típicamente, tales compuestos pueden exhibir propiedades como solubilidad en disolventes polares, y pueden participar en enlaces de hidrógeno debido a la presencia de grupos funcionales hidroxilo y carbonilo. La funcionalidad de éster metílico sugiere que puede sufrir hidrólisis para liberar el ácido correspondiente, lo que podría afectar aún más sus interacciones biológicas. En general, las características estructurales de este compuesto lo posicionan como un candidato para la investigación en química medicinal, particularmente en el desarrollo de agentes antivirales o anticancerígenos.

Fórmula: C₁₂H₁₆N₂O₈

InChI: InChI=1/C12H16N2O8/c1-21-7(16)2-5-3-14(12(20)13-10(5)19)11-9(18)8(17)6(4-15)22-11/h3,6,8-9,11,15,17-18H,2,4H2,1H3,(H,13,19,20)/t6-,8-,9-,11-/m1/s1

Clave InChI: InChIKey=YIZYCHKPHCPKHZ-PNHWDRBUSA-N

SMILES: O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)NC(=O)C(CC(OC)=O)=C2

Sinónimos:

• 5-Carboxymethyluridine methyl ester
• 5-Methoxycarbonyl methyl uridine
• 5-Pyrimidineacetic acid, 1,2,3,4-tetrahydro-2,4-dioxo-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-, methyl ester
• Methyl 1,2,3,4-tetrahydro-2,4-dioxo-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-5-pyrimidineacetate
• Uridine, 5-(2-Methoxy-2-Oxoethyl)-
• 5-Pyrimidineacetic acid, 1,2,3,4-tetrahydro-2,4-dioxo-1-β-D-ribofuranosyl-, methyl ester
• 5-(2-Methoxy-2-oxoethyl)uridine
• Methyl 1,2,3,4-tetrahydro-2,4-dioxo-1-β-D-ribofuranosyl-5-pyrimidineacetate
• 5-Pyrimidineacetic acid, 1,2,3,4-tetrahydro-2,4-dioxo-1-beta-D-ribofur anosyl-, methyl ester
• 5-(Methoxycarbonyl) methyluridine (MCM5U
• 5-<(methylcarboxy)methyl>uridine
• 1,2,3,4-Tetrahydro-2,4-dioxo-1-beta-D-ribofuranosyl-5-pyrimidineacetic Acid Methyl Ester, 5-(Methoxy carbonyl)-methyluridine, Uridine 5-acetic acid methyl ester
• 1,2,3,4-Tetrahydro-2,4-dioxo-1-beta-D-ribofuranosyl-5-pyriMidineacetic Acid Methyl Ester
• 5-(Methoxycarbonyl) methyluridine (MCM5U),Uridine 5-acetic acid methyl ester, RNA mCm5U

5-Pyrimidineacetic acid, 1,2,3,4-tetrahydro-2,4-dioxo-1-β-D-ribofuranosyl-, methyl ester

CAS: 29428-50-0

Fórmula: C₁₂H₁₆N₂O₈

Pureza: 98%

Forma y color: Solid

Peso molecular: 316.2640

Ref: IN-DA002YCW

5-(Methoxycarbonyl)methyluridine

CAS: 29428-50-0

5-(Methoxycarbonyl)methyluridine

Pureza: ≥98%

Peso molecular: 316.26g/mol

Ref: 54-BUP20284

5-(Methoxycarbonyl)methyluridine

CAS: 29428-50-0

5-(Methoxycarbonyl)methyluridine is an important modifying nucleotide in tRNAs, and the lack of the mcm5U modification leads to increased protein aggregation.

Fórmula: C₁₂H₁₆N₂O₈

Pureza: 99.71%

Forma y color: Solid

Peso molecular: 316.26

Ref: TM-TNU0040

5-Methoxycarbonyl Methyl Uridine

Producto controlado

CAS: 29428-50-0

Applications 5-Methoxycarbonyl methyl uridine is a nucleoside constituent of yeast transfer RNA. 5-Methoxycarbonyl methyl uridine is also a derivative of 5-carboxymethyluridine, a carboxyl-containing nucleoside that was isolated from transfer RNA of Baker’s Yeast.
References Gray, M. & Lane, B.: Biochemistry, 7, 3441 (1968); Tumaitis, T. & Lane, B.: BBA-Nuc. Acid. Prot. Synth., 224, 391 (1970)

Fórmula: C₁₂H₁₆N₂O₈

Forma y color: Neat

Peso molecular: 316.26

Ref: TR-M261615

5-Methoxycarbonylmethyluridine

CAS: 29428-50-0

5-Methoxycarbonylmethyluridine is a nucleoside that is a precursor in the synthesis of other nucleotides. It has been shown to have potential as a biomarker for various diseases, such as metabolic disorders and hepatic steatosis. 5-Methoxycarbonylmethyluridine also inhibits the activity of methyltransferases, which are enzymes that catalyze the transfer of methyl groups from S-adenosylmethionine to substrates. It is also used as a model system for polymerase chain reaction in cancer research, because it has been shown to inhibit DNA replication by blocking the incorporation of uracil into DNA.
5-Methoxycarbonylmethyluridine has been found at high levels in fetal bovine serum and eukaryotic cells, but not in prokaryotes or cancerous tissues.

Fórmula: C₁₂H₁₆N₂O₈

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 316.26 g/mol

Ref: 3D-NM45525