CAS 29457-07-6

Ticarcilina disódica

Descripción:

Ticarcilina disódica es un antibiótico penicilínico semisintético que se utiliza principalmente para tratar infecciones causadas por bacterias Gram-negativas susceptibles. Se caracteriza por su actividad de amplio espectro, particularmente contra Pseudomonas aeruginosa y otras Enterobacteriaceae. El compuesto es una sal disódica de ticarcilina, que mejora su solubilidad en soluciones acuosas, haciéndolo adecuado para la administración intravenosa. La ticarcilina actúa inhibiendo la síntesis de la pared celular bacteriana, lo que lleva a la lisis celular y a la muerte. A menudo se utiliza en combinación con otros antibióticos, como el ácido clavulánico, para superar los mecanismos de resistencia. La sustancia se administra típicamente en un entorno clínico, y su farmacocinética incluye una rápida distribución en los tejidos del cuerpo, siendo la excreción renal la principal vía de eliminación. Los efectos secundarios comunes pueden incluir reacciones alérgicas, trastornos gastrointestinales y alteraciones en la coagulación sanguínea. Al igual que con todos los antibióticos, se recomienda realizar pruebas de susceptibilidad adecuadas para garantizar la efectividad contra patógenos específicos.

Fórmula: C₁₅H₁₆N₂O₆S₂·2Na

InChI: InChI=1S/C15H16N2O6S2.2Na/c1-15(2)9(14(22)23)17-11(19)8(12(17)25-15)16-10(18)7(13(20)21)6-3-4-24-5-6;;/h3-5,7-9,12H,1-2H3,(H,16,18)(H,20,21)(H,22,23);;/t7-,8-,9+,12-;;/m1../s1

Clave InChI: InChIKey=IPRJTUDVZGEREZ-QBGWIPKPSA-N

SMILES: N(C([C@H](C(O)=O)C=1C=CSC1)=O)[C@H]2[C@@]3(N([C@@H](C(O)=O)C(C)(C)S3)C2=O)[H].[Na]

Sinónimos:

• 3-Thiophenemalonamic acid, N-(2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-6-yl)-, disodium salt, <span class="text-smallcaps">D</span>-(-)-
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[(carboxy-3-thienylacetyl)amino]-3,3-dimethyl-7-oxo-, disodium salt, [2S-[2α,5α,6β(S*)]]-
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-2-carboxy-2-(3-thienyl)acetyl]amino]-3,3-dimethyl-7-oxo-, sodium salt (1:2), (2S,5R,6R)-
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-carboxy-3-thienylacetyl]amino]-3,3-dimethyl-7-oxo-, disodium salt, (2S,5R,6R)-
• 6-<span class="text-smallcaps">D</span>(-)-(α-Carboxy-3-thienylacetamido)penicillanic acid disodium salt
• 6-<span class="text-smallcaps">D</span>-(-)-α-Carboxy-3-thienylmethylacetamido penicillanic acid
• Ab 2288
• Brl 2288
• Disodium ticarcillin
• Monapen
• Ticar
• Ticarcillin Disodium
• Ticarcillin disodium salt
• Ticarcillin sodium
• Ticarcillin sodium salt
• Ticarpen
• disodium (2R,5R,6R)-6-{[carboxylato(thiophen-3-yl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
• disodium (2S,5R,6R)-6-{[(2R)-2-carboxylato-2-thiophen-3-ylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
• α-Carboxy-3-thienylmethylpenicillin disodium salt
• 3-Thiophenemalonamic acid, N-(2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-6-yl)-, disodium salt, D-(-)-

Ticarcillin sodium

CAS: 29457-07-6

Ticarcillin sodium

Pureza: ≥95%

Peso molecular: 430.41g/mol

Ref: 54-BUP16405

Ticarcillin sodium

CAS: 29457-07-6

Ticarcillin sodium: a semisynthetic, broad-spectrum antibiotic effective against various aerobic and anaerobic bacteria.

Fórmula: C₁₅H₁₆N₂O₆S₂·2Na

Pureza: 99.09%

Forma y color: Solid

Peso molecular: 430.41

Ref: TM-T6706

Ticarcillin Disodium Salt (Contain 10% Methanol)

Producto controlado

CAS: 29457-07-6

Stability Hygroscopic
Applications The disodium salt of Ticarcillin, a carboxypenicillin belonging to the beta-lactam class of antibiotics. Ticarcillin is an injectable antibiotic used in the treatment of infections caused by gram-negative bacteria, particularly Pseudomonas aeruginosa.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Paisley, J.W. et al.: Antimicrob. Agents Chemother., 14, 224 (1978); Fass, R.J. et al.: Rev. Infect. Dis., 2, 841 (1980); Husson, M.O. et al.: Drugs Exp. Clin. Res., 9, 843 (1983);

Fórmula: C₁₅H₁₄N₂O₆S₂·2Na

Forma y color: Neat

Peso molecular: 428.39

Ref: TR-T437901

Ticarcillin disodium

CAS: 29457-07-6

Ticarcillin is a bactericidal antibiotic that is used to treat many types of infections caused by gram-positive bacteria, such as Streptococcus pneumoniae, Enterococcus faecalis and Enterococcus faecium. Ticarcillin has been shown to be effective against antibiotic-resistant strains of bacteria, including multidrug efflux pumps. This drug also has been shown to inhibit the growth of gram-negative bacteria such as Escherichia coli and Pseudomonas aeruginosa. Ticarcillin is used in combination with clavulanic acid for the treatment of infections caused by beta-lactamase producing organisms. It is also used in wastewater treatment to inhibit the growth of gram-negative bacteria that are resistant to other antibiotics. Ticarcillin can interfere with other medications by inhibiting their metabolism through cytochrome P450 enzymes or through competition for protein binding sites.

Fórmula: C₁₅H₁₆N₂Na₂O₆S₂

Pureza: Min. 80.0 Area-%

Forma y color: White Powder

Peso molecular: 430.41 g/mol

Ref: 3D-FC75007

Ticarcillin Disodium Salt-13C3 (Contain 10% Methanol)

Producto controlado

CAS: 29457-07-6

Fórmula: C₃C₁₂H₁₄N₂Na₂O₆S₂

Forma y color: Neat

Peso molecular: 431.369

Ref: TR-T437902