CAS 2992670-33-2

PROTAC EGFR degrader 9

CAS: 2992670-33-2

PROTACEGFRdegrader 9 (Compound C6) is an orally active, CRBN-based PROTAC EGFR degrader. It has a DC50 of 10.2 nM and a Kd of 240.2 nM against EGFRL858R/T790M/C797S. PROTACEGFRdegrader 9 demonstrates effective degradation activity against various EGFR mutants while not affecting EGFRWT.

Fórmula: C₄₅H₄₈F₃N₉O₆S

Peso molecular: 899.98

Ref: TM-T209870