CAS 30246-33-4

ácido (6R-trans)-7-amino-3-[[(5-metil-1,3,4-tiadiazol-2-il)tio]metil]-8-oxo-5-tia-1-azabiciclo[4.2.0]oct-2-eno-2-carboxílico

Descripción:

La sustancia química conocida como ácido (6R-trans)-7-amino-3-[[(5-metil-1,3,4-tiadiazol-2-il)tio]metil]-8-oxo-5-tia-1-azabiciclo[4.2.0]oct-2-eno-2-carboxílico, con el número CAS 30246-33-4, es un compuesto sintético que pertenece a la clase de los antibióticos. Presenta una estructura bicíclica, que es característica de ciertos antibióticos beta-lactámicos, y contiene un grupo tiadiazol que contribuye a su actividad biológica. La presencia de un grupo amino y un grupo funcional ácido carboxílico sugiere interacciones potenciales con objetivos biológicos, mejorando sus propiedades farmacológicas. Este compuesto es conocido por su actividad antibacteriana, particularmente contra una variedad de bacterias Gram-positivas y Gram-negativas. Sus características estructurales únicas también pueden influir en su solubilidad, estabilidad y mecanismo de acción. Al igual que con muchos antibióticos, comprender sus características es crucial para evaluar su potencial terapéutico y perfil de seguridad en aplicaciones clínicas.

Fórmula: C₁₁H₁₂N₄O₃S₃

InChI: InChI=1/C11H12N4O3S3/c1-4-13-14-11(21-4)20-3-5-2-19-9-6(12)8(16)15(9)7(5)10(17)18/h6,9H,2-3,12H2,1H3,(H,17,18)/t6-,9-/m0/s1

Clave InChI: InChIKey=HJSGHKMSDOLGJJ-HZGVNTEJSA-N

SMILES: C(O)(=O)C=1N2[C@@]([C@H](N)C2=O)(SCC1CSC=3SC(C)=NN3)[H]

Sinónimos:

• (6R,7R)-7-Amino-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6S,7S)-7-ammonio-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• (7R)-7-amino-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-, (6R-trans)-
• 7-Amino-3-(5-methyl-1,3,4-thiadiazol-2-ylthiomethyl)-δ-3-cephem-4-carboxylic acid
• 7-Amino-3-[(2-methyl-1,3,4-thiadiazol-5-ylthio)methyl]-3-cephem-4-carboxylic acid
• 7-Amino-3-[(5-Methyl-1,3,4-Thiadiazol-2-Yl)Thiomethyl]Cephalosphoranic Acid
• 7-Amino-3-[(5-methyl-1,3,4-thiadiazol-2-ylthio)methyl]-3-cephem-4-carboxylic acid
• 7-Tda
• 7-Zaca
• Parent nucleus of cefazedone
• (6R-trans)-7-Amino-3-(((5-methyl-1,3,4-thiadiazol-2-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid
• Cefazolin EP Impurity A
• Cefuroxime nucleus (7-TDA)
• (7r)-7-amino-3-[(5-methyl-1,3,4-thiadiazol-2-yl)thiomethyl]-3-cephem-4-carboxylicacid
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 7-amino-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-, (6R,7R)-
• Parent nucleus of cefazedone (7-TDA)
• Cefazolin Impurity 7(Cefazolin EP Impurity A)
• Cefazolin USP Impurity K
• TDA
• 3,5-Dichloro-4-hydroxypyridine，7-Amino-3-[(5-methyl-1,3,4-thiadiazol- 2-ylthio)methyl]-3-cephem-4- carboxylic Acid
• Cefazolin Impurity EP-A
• 7-Amino-3-[[(5-methyl-1,3,4-thiadiazol-2yl)thiomethyl]-3-cephalosporanicacid
• 7-Amino-3-[(5-methyl-1,3,4-thiadiazol-2-yl)-thiomethyl]-cephalosporanic aci
• 7-ammonio-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• Cefazolin IMpurity A
• (6R)-7α-Amino-3-(5-methyl-1,3,4-thiadiazol-2-ylthiomethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• Cefazolin Sodium Impurity A
• (6R,7R)-7-amino-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 7-Amino-3-([5-methyl-1,3,4-thiadiazol-2-yl] thiomethyl)-3-cephem-4-carboxylic acid

7-Amino-3-[(5-Methyl-1,3,4-Thiadiazol-2-Yl)Thiomethyl]Cephalosphoranic Acid

CAS: 30246-33-4

Fórmula: C₁₁H₁₂N₄O₃S₃

Pureza: 97%

Forma y color: Solid

Peso molecular: 344.4330

Ref: IN-DA00BDYC

Cefazolin EP Impurity A

CAS: 30246-33-4

Fórmula: C₁₁H₁₂N₄O₃S₃

Forma y color: White To Off-White Solid

Peso molecular: 344.44

Ref: 4Z-C-9611

7-Amino-3-[(5-Methyl-1,3,4-Thiadiazol-2-yl)Thiomethyl]Cephalosphoranic Acid

CAS: 30246-33-4

7-Amino-3-[(5-Methyl-1,3,4-Thiadiazol-2-yl)Thiomethyl]Cephalosphoranic Acid

Pureza: 99%

Peso molecular: 344.44g/mol

Ref: 54-OR1012052

7-ZACA

CAS: 30246-33-4

7-ZACA (cefazolin decarboxylated) is a decarboxylated derivative of cefazolin.

Fórmula: C₁₁H₁₂N₄O₃S₃

Pureza: 99.73%

Forma y color: Solid

Peso molecular: 344.42

Ref: TM-T66940

7-Amino-3-[(5-methyl-1,3,4-thiadiazol-2-ylthio)methyl]-3-cephem-4-carboxylic Acid

Producto controlado

CAS: 30246-33-4

Impurity Cefazolin EP Impurity A
Applications 7-Amino-3-[(5-methyl-1,3,4-thiadiazol-2-ylthio)methyl]-3-cephem-4-carboxylic Acid (Cefazolin EP Impurity A) is a substrate used in the assessment of immobilized PGA orientation and in the synthesis of beta lactam antibiotics.
References Serra, I. et al.: Anal. Bioanal. Chem., 405, 745 (2013); Terreni, M. et al.: App. Microbiol. Biotech., 77, 579 (2007); Kurochkina, V. et al.: Biocat. Biotransform., 20, 35 (2002)

Fórmula: C₁₁H₁₂N₄O₃S₃

Forma y color: Neat

Peso molecular: 344.43

Ref: TR-A618190

(6R,7R)-7-Amino-3-(((5-methyl-1,3,4-thiadiazol-2-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

CAS: 30246-33-4

Pureza: 97.0%

Peso molecular: 344.4200134277344

Ref: 10-F546079

Cefazolin impurity A

CAS: 30246-33-4

Cefazolin impurity A is a by-product in the synthesis of Cefazolin, which is a drug product. It has CAS No. 30246-33-4 and is used as an impurity standard for analytical purposes. The Impurity Standard is also known as Metabolite A. Research and Development (R&D) studies are needed to identify the appropriate analytical impurities for this API, which will be reported on Pharmacopoeia's List of Impurities for reference. The high purity and custom synthesis of this API makes it ideal for use in R&D studies, HPLC standards, or niche markets.
CAS No.: 30246-33-4
Synonyms: Metabolite A
Formula: C11H14N2O5S
Molecular weight: 289.24 g/mol
Appearance: white solid powder

Fórmula: C₁₁H₁₂N₄O₃S₃

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 344.44 g/mol

Ref: 3D-IC63651

Cefazolin EP Impurity A

CAS: 30246-33-4

Fórmula: C₁₁H₁₂N₄O₃S₃

Peso molecular: 344.42

Ref: ST-EA-CP-C149001