CAS 303-26-4

Norclorciclizina

Descripción:

Norclorciclizina, con el número CAS 303-26-4, es un compuesto químico que pertenece a la clase de los antihistamínicos. Es un derivado de la ciclizina, que se utiliza principalmente por sus propiedades antieméticas y antihistamínicas. Norclorciclizina exhibe una variedad de efectos farmacológicos, incluida la capacidad de aliviar los síntomas asociados con el mareo por movimiento y las alergias. El compuesto se caracteriza por sus características estructurales, que incluyen un anillo de piperazina y un sistema aromático clorado, lo que contribuye a su actividad biológica. Se administra típicamente en varias formulaciones, y su eficacia se atribuye a su capacidad para bloquear los receptores de histamina H1. Además, Norclorciclizina puede tener efectos sedantes, lo que lo hace útil en ciertos contextos terapéuticos. Sin embargo, al igual que muchos antihistamínicos, también puede causar efectos secundarios como somnolencia, boca seca y mareos. Su perfil de seguridad y farmacocinética son consideraciones importantes en el uso clínico, y es esencial adherirse a las dosis recomendadas para minimizar los efectos adversos.

Fórmula: C₁₇H₁₉ClN₂

InChI: InChI=1/C17H19ClN2/c18-16-8-6-15(7-9-16)17(14-4-2-1-3-5-14)20-12-10-19-11-13-20/h1-9,17,19H,10-13H2/p+2/t17-/m0/s1

Clave InChI: InChIKey=UZKBSZSTDQSMDR-UHFFFAOYSA-N

SMILES: C(C1=CC=C(Cl)C=C1)(C2=CC=CC=C2)N3CCNCC3

Sinónimos:

• (±)-1-(p-Chlorobenzhydryl)piperazine
• 1-(4-Chloro-α-phenylbenzyl)piperazine
• 1-(4-Chlorobenzhydryl)-piperizine
• 1-(4-Chlorophenylmethyl)piperazine
• 1-(α-Phenyl-4-chlorobenzyl)piperazine
• 1-[(4-Chlorophenyl) phenylmethyl] piperazine
• 1-[(R)-(4-chlorophenyl)(phenyl)methyl]piperazinediium
• 1-[(S)-(4-chlorophenyl)(phenyl)methyl]piperazinediium
• 1-[4-Chlorophenyl) (Phenyl)Methyl] Piperazine
• 4-(4-Chlorobenzhydryl)piperazine
• Chlorophenyl)(phenyl)methyl)piperazine,1-((4-
• N-(4-Chlorobenzhydryl)piperazine
• N-(4-Chlorophenyl)phenylmethylpiperazine
• N-(p-Chlorobenzhydryl)-piperazine
• NSC 86164
• Norchlorcyclizine
• Piperazine, 1-(p-chloro-α-phenylbenzyl)-
• Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-
• N-(4-CHLOROBENZYLHYDRYL)PIPERAZINE
• Piperazine, 1-(p-chloro-alpha-phenylbenzyl)-
• 1-((4-chlorophenyl)phenylmethyl)-piperazin
• 1-(4-Chloro-alpha-phenylbenzyl)piperazine
• TIMTEC-BB SBB002998
• 1-(4-CHLOROBENZHYDRYL)PIPERAZINE
• 1-(4-CHLORODIPHENYLMETHYL)-PIPERAZINE
• 1-(p-chloro-alpha-phenylbenzyl)-piperazin
• Piperazine, 1-(alpha-(4-chlorophenyl)benzyl)-
• AKOS BBS-00003606
• 1-(4-CHLOROBENZHYDRYL)PIPERAZINE, TECH.,
• 1-(alpha-Phenyl-4-chlorobenzyl)piperazine
• 1-[(4-CHLORO-PHENYL)-PHENYL-METHYL]-PIPERAZINE

1-(4-Chlorobenzhydryl)piperazine

CAS: 303-26-4

Fórmula: C₁₇H₁₉ClN₂

Pureza: >98.0%(GC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 286.80

Ref: 3B-C1611

1-[(4-Chlorophenyl)phenylmethyl]piperazine

CAS: 303-26-4

Forma y color: Neat

Ref: 61-FOR0380.01

MECLOZINE IMPURITY H CRS

CAS: 303-26-4

MECLOZINE IMPURITY H CRS

Fórmula: C₁₇H₁₉ClN₂

Forma y color: May Be Present In Various Forms. Powder.

Peso molecular: 286.7992

Ref: 41-Y0001311

CETIRIZINE IMPURITY A CRS

CAS: 303-26-4

CETIRIZINE IMPURITY A CRS

Fórmula: C₁₇H₁₉ClN₂

Peso molecular: 286.7992

Ref: 41-C0980651

Hydroxyzine Related Compound A (1-[(4-Chlorophenyl)phenylmethyl]piperazine)

CAS: 303-26-4

Compounds containing a pyrimidine ring, whether or not hydrogenated, or piperazine ring in the structure, nesoi

Fórmula: C₁₇H₁₉ClN₂

Forma y color: Powder

Peso molecular: 286.12368

Ref: 45-1333058

Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-

CAS: 303-26-4

Fórmula: C₁₇H₁₉ClN₂

Pureza: 95%

Forma y color: Solid

Peso molecular: 286.7992

Ref: IN-DA002ZJZ

Norchlorcyclizine, 10mM (in DMSO)

CAS: 303-26-4

Norchlorcyclizine, 10mM (in DMSO)

Pureza: ≥95%

Peso molecular: 286.8g/mol

Ref: 54-BUP19283

Cetirizine EP Impurity A (Levocetirizine EP Impurity I, Meclozine EP Impurity H, Hydroxyzine EP Impurity A, Hydroxyzine USP Related Compound A)

CAS: 303-26-4

Fórmula: C₁₇H₁₉ClN₂

Forma y color: Off-White Solid

Peso molecular: 286.80

Ref: 4Z-C-208

(RS)-1-[(4-Chlorophenyl)phenylmethyl]piperazine

Producto controlado

CAS: 303-26-4

Fórmula: C₁₇H₁₉ClN₂

Forma y color: Neat

Peso molecular: 286.80

Ref: 86-MM0380.01

1-(4-Chlorobenzhydryl)piperazine

CAS: 303-26-4

1-(4-Chlorobenzhydryl)piperazine

Pureza: 98%

Peso molecular: 286.80g/mol

Ref: 54-OR4570

Norchlorcyclizine

CAS: 303-26-4

Norchlorcyclizine (C-10) is a partially selective NPR-B inhibitor. It also is an inhibitor of human tyrosyl-DNA phosphodiesterase 1.

Fórmula: C₁₇H₁₉ClN₂

Pureza: 97.27%

Forma y color: White Solid

Peso molecular: 286.8

Ref: TM-T20499

Buclizine Impurity 2

CAS: 303-26-4

Fórmula: C₁₇H₁₉ClN₂

Peso molecular: 286.80

Ref: ST-EA-CP-B30002

Cetirizine EP Impurity A

CAS: 303-26-4

Fórmula: C₁₇H₁₉ClN₂

Peso molecular: 286.79

Ref: ST-EA-CP-C14001

Levocetirizine EP Impurity I

CAS: 303-26-4

Fórmula: C₁₇H₁₉ClN₂

Peso molecular: 286.8

Ref: ST-EA-CP-L15001

1-[(4-Chlorophenyl)phenylmethyl]piperazine

Producto controlado

CAS: 303-26-4

Impurity Hydroxyzine EP Impurity A; Cetirizine Impurity A; Cetirizine USP A
Applications A metabolite of Cetirizine (C281100) and Hydroxyzine. Citirizine impurity A. Hydroxyzine EP Impurity A. Cetirizine Impurity A. Cetirizine USP A.
References Lewis, T., et al.: Bioorg. Med. Chem. Lett., 14, 2265 (2004),

Fórmula: C₁₇H₁₉ClN₂

Forma y color: Neat

Peso molecular: 286.8

Ref: TR-C379575

1-[(4-Chlorophenyl)(phenyl)methyl]piperazine

CAS: 303-26-4

Fórmula: C₁₇H₁₉ClN₂

Pureza: 90.0%

Forma y color: Solid

Peso molecular: 286.8

Ref: 10-F068945

1-[(4-Chlorophenyl)phenylmethyl]piperazine

Producto controlado

CAS: 303-26-4

1-[(4-Chlorophenyl)phenylmethyl]piperazine is an analytical reagent that is used in the determination of meclozine, a drug used for the treatment of nausea and vomiting. 1-[(4-Chlorophenyl)phenylmethyl]piperazine is a nucleophile, which means that it can donate electrons to other molecules. It can be used as a catalyst to increase the rate of chemical reactions. 1-[(4-Chlorophenyl)phenylmethyl]piperazine may also be used in wastewater treatment because it has been shown to have phospholipidosis inhibiting properties. The levorotatory form (1R-enantiomer) of this compound has been shown to inhibit protein synthesis in vitro and is an amine oxidase inhibitor that binds to proteins with nitrogen atoms. This nucleophilic compound may also be converted into an n-oxide or dinucleotide phosphate by hydrochloric acid and

Fórmula: C₁₇H₁₉ClN₂

Pureza: Min. 95%

Peso molecular: 286.8 g/mol

Ref: 3D-FC20350