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CAS 3032576-92-1

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  • INNO-220
    Targetmol
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    INNO-220

    CAS:
    INNO-220 is an orally active, CRBN-dependent molecular glue degrader that targets CK1α. By degrading CK1α, INNO-220 induces cell cycle arrest at the G0/G1 phase and triggers apoptosis (Apoptosis). It disrupts the assembly and function of the CARD11/BCL10/MALT1 complex, inhibiting the NF-κB signaling pathway in T cells and lymphoma cells with activating mutations in CARD11. INNO-220 offers a novel direction for lymphoma research.
    Fórmula:C23H20N4O3
    Forma y color:Solid
    Peso molecular:400.43

    Ref: TM-T211026