CAS 304-20-1

Clorhidrato de hidralazina

Descripción:

Clorhidrato de hidralazina es un compuesto farmacéutico utilizado principalmente como agente antihipertensivo para manejar la hipertensión. Se clasifica como un vasodilatador, lo que significa que actúa relajando los vasos sanguíneos, reduciendo así la carga de trabajo del corazón. La fórmula química de Clorhidrato de hidralazina es C8H8N4·HCl, lo que indica que contiene un grupo hidrazina, que es esencial para su actividad biológica. Este compuesto se administra típicamente por vía oral o intravenosa y es conocido por su rápido inicio de acción. Clorhidrato de hidralazina se caracteriza por su apariencia cristalina blanca a blanco sucio y es soluble en agua, lo que lo hace adecuado para diversas formulaciones. Los efectos secundarios comunes pueden incluir dolor de cabeza, palpitaciones y trastornos gastrointestinales. Es importante monitorear a los pacientes por posibles reacciones adversas, como el síndrome similar al lupus, especialmente con el uso a largo plazo. En general, Clorhidrato de hidralazina desempeña un papel significativo en el manejo de la hipertensión, particularmente en casos donde otros tratamientos pueden no ser efectivos.

Fórmula: C₈H₈N₄·ClH

InChI: InChI=1S/C8H8N4.ClH/c9-11-8-7-4-2-1-3-6(7)5-10-12-8;/h1-5H,9H2,(H,11,12);1H

Clave InChI: InChIKey=ZUXNZUWOTSUBMN-UHFFFAOYSA-N

SMILES: N(N)=C1C=2C(C=NN1)=CC=CC2.Cl

Sinónimos:

• (Phthalazin-1-yl)hydrazine hydrochloride
• 1(2H)-Phthalazinone hydrazone
• 1(2H)-Phthalazinone, hydrazone, monohydrochloride
• 1-Hydrazinophthalazine hydrochloride
• 1-Hydrazinophthalazine monohydrochloride
• 1-Hydrazinylphthalazine
• 1-Hydrazinylphthalazine Hydrochloride (1:1)
• 1-Hydrazinylphthalazine hydrochloride
• Apresoline hydrochloride
• Apulon
• Hydralazine chloride
• Hydralazine hcl
• Hydralazine monohydrochloride
• Lopres
• Phthalazine, 1-hydrazino-, monohydrochloride
• Phthalazine, 1-hydrazinyl-, hydrochloride (1:1)

1-Hydrazinophthalazine Hydrochloride

CAS: 304-20-1, 86-54-4

Fórmula: C₈H₈N₄·HCl

Pureza: >99.0%(T)(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 196.64

Ref: 3B-H0409

1-Hydrazinophthalazine hydrochloride, 98%

CAS: 304-20-1

A monoamine oxidase inhibitor1-Hydrazinophthalazine hydrochloride is a non-nucleoside analog that inhibits DNA methylation and reactivates the expression of tumor suppressor genes. It acts as a non-selective MAO-A/B inhibitor and semicarbazide sensitive amine oxidase inhibitor. Further, it serves as

Fórmula: C₈H₈N₄•HCl

Pureza: 98%

Forma y color: White to pale cream, Powder or crystals or crystalline powder

Peso molecular: 196.64

Ref: 02-B22995

HYDRALAZINE HYDROCHLORIDE CRS

CAS: 304-20-1

HYDRALAZINE HYDROCHLORIDE CRS

Fórmula: C₈H₉ClN₄

Forma y color: Crystalline Powder. White. Powder.

Peso molecular: 196.6369

Ref: 41-H1120000

Hydralazine Hydrochloride

CAS: 304-20-1

Hydralazine hydrochloride

Fórmula: C₈H₈N₄·HCl

Forma y color: White Off-White Crystalline Powder

Peso molecular: 160.0749

Ref: 45-1313006

Phthalazine, 1-hydrazinyl-, hydrochloride (1:1)

CAS: 304-20-1

Fórmula: C₈H₉ClN₄

Pureza: 98%

Forma y color: Solid

Peso molecular: 196.6369

Ref: IN-DA003006

Hydralazine hydrochloride

CAS: 304-20-1

Hydralazine hydrochloride, an antihypertensive phthalazine, induces vasodilation and may inhibit tumor DNA methylation.

Fórmula: C₈H₉ClN₄

Pureza: 99.85% - 99.86%

Forma y color: Yellow Crystals White Crystalline Solid

Peso molecular: 196.64

Ref: TM-T1613

Hydralazine hydrochloride

CAS: 304-20-1

Hydralazine hydrochloride

Pureza: ≥98%

Peso molecular: 196.64g/mol

Ref: 54-BUP17906

Hydralazine hydrochloride

CAS: 304-20-1

Fórmula: C₈H₈N₄HCl

Peso molecular: 196.64

Ref: 7W-GL6824

Hydralazine HCl (Dihydralazine EP Impurity C HCl)

CAS: 304-20-1

Fórmula: C₈H₈N₄·HCl

Forma y color: White To Off-White Solid

Peso molecular: 160.18 36.46

Ref: 4Z-H-135

1-hydrazinyl-Phthalazine hydrochloride

CAS: 304-20-1

1-hydrazinyl-Phthalazine hydrochloride

Pureza: 98%

Peso molecular: 196.64g/mol

Ref: 54-OR1009501

Hydralazine hydrochloride

CAS: 304-20-1

Fórmula: C₈H₈N₄·ClH

Forma y color: Neat

Peso molecular: 196.64

Ref: 04-C14219100

Hydralazine Hydrochloride

Producto controlado

CAS: 304-20-1

Applications Hydralazine is a non-nucleoside analog that inhibits DNA methylation and reactivates the expression of tumour suppressor genes (1,2,3). It is also a non-selective MAO-A/B inhibitor and a semicarbazide-sensitive amine oxidase inhibitor. Antihypertensive.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References (1) Siedlecki, P., et al.: J. Med. Chem. 49, 678 (2006) (2) Link, P., et al.: Cancer Res., 68, 9358 (2008) (3) Singh, N., et al.: ChemMedChem., 4, 792 (2009)

Fórmula: C₈H₈N₄·ClH

Forma y color: Off-White

Peso molecular: 196.64

Ref: TR-H716531

1-Hydrazinylphthalazine hydrochloride

CAS: 304-20-1

Fórmula: C₈H₉ClN₄

Pureza: 98%

Forma y color: Solid, White to very pale yellow powder

Peso molecular: 196.64

Ref: 10-F236804

Hydralazine hydrochloride

CAS: 304-20-1

Hydralazine hydrochloride is a drug used to treat high blood pressure. It is an inhibitor of the enzyme phosphodiesterase, which leads to increased levels of cAMP and vasodilation in the lungs. Hydralazine hydrochloride has been shown to induce renal injury, specifically by inhibiting the synthesis of prostaglandins that protect the kidneys from damage. This drug can also cause cardiac effects such as tachycardia and arrhythmias. Hydralazine hydrochloride interacts with other drugs, including Candesartan cilexetil and other drugs that inhibit phosphodiesterase, leading to an increase in blood pressure. Hydralazine hydrochloride binds to guanine nucleotide-binding proteins (G proteins) on neural cells and increases the rate constant for G protein activation.

Fórmula: C₈H₉ClN₄

Pureza: Min. 95%

Forma y color: White Powder

Peso molecular: 196.64 g/mol

Ref: 3D-FH23871