CAS 306-07-0

Clorhidrato de pargilina

Descripción:

Clorhidrato de pargilina es un compuesto farmacéutico reconocido principalmente por su papel como inhibidor de la monoaminooxidasa (IMAO). Se utiliza comúnmente en el tratamiento de ciertos tipos de depresión y se ha investigado por sus propiedades neuroprotectoras. La sustancia aparece como un polvo cristalino blanco a blanco amarillento y es soluble en agua, lo que facilita su administración en entornos clínicos. La pargilina actúa inhibiendo la enzima monoaminooxidasa, aumentando así los niveles de neurotransmisores como la serotonina, la norepinefrina y la dopamina en el cerebro, lo que puede ayudar a aliviar los síntomas depresivos. Su estructura química incluye un anillo de piridina, lo que contribuye a su actividad farmacológica. Si bien es efectiva, el uso de Clorhidrato de pargilina requiere un monitoreo cuidadoso debido a las posibles restricciones dietéticas e interacciones con otros medicamentos, particularmente aquellos que contienen tiramina, lo que puede llevar a crisis hipertensivas. Al igual que con cualquier IMAO, los pacientes deben ser informados sobre los riesgos y beneficios asociados con su uso.

Fórmula: C₁₁H₁₄ClN

InChI: InChI=1/C11H13N.ClH/c1-3-9-12(2)10-11-7-5-4-6-8-11;/h1,4-8H,9-10H2,2H3;1H

Clave InChI: InChIKey=BCXCABRDBBWWGY-UHFFFAOYSA-N

SMILES: C(N(CC#C)C)C1=CC=CC=C1.Cl

Sinónimos:

• A 19120
• Benzenemethanamine, N-methyl-N-2-propyn-1-yl-, hydrochloride (1:1)
• Benzenemethanamine, N-methyl-N-2-propynyl-, hydrochloride
• Benzylamine, N-methyl-N-2-propynyl-, hydrochloride
• Eutonyl
• Eutonyl-ten
• Methylbenzylpropynylamine hydrochloride
• Mo 911
• N-Benzyl-N-methyl-2-propynylamine hydrochloride
• N-Methyl-N-(2-propynyl)benzylamine hydrochloride
• N-Methyl-N-2-propynylbenzylamine hydrochloride
• N-benzyl-N-methylprop-2-yn-1-amine
• N-benzyl-N-methylprop-2-yn-1-amine hydrochloride (1:1)
• N-methyl-N-propargylbenzylamine hydro-chloride
• NSC 43798
• Parguline HCL
• Pargyline Hcl
• n-methyl-n-2-propynyl-benzylaminhydrochloride
• PARGYLINE HYDROCHLOR
• PARGYLINE HYDROCHLORIDE MAO INHIBITOR
• N-METHYL-N-PROPARGYLBENZYLAMINE HYDROCHLORIDE
• benzylmethylpropynylaminehydrochloride
• N-methyl-N-(phenylmethyl)-2-propyn-1-amine hydrochloride
• n-benzyl-n-methyl-2-propynylaminhydrochloride
• N-Methyl-npropargylbenzeneMethanaMine HCl
• n-benzyl-n-methyl-2-propynylaminehydrochloride
• N-METHYL-N-(2-PROPYNY)BENZYLAMINE HYDROCHLORIDE
• N-benzyl-N-methylprop-2-yn-1-amine hydrochloride
• N-methyl-N-(phenylmethyl)prop-2-yn-1-amine hydrochloride
• Pargyline Hydrochloride (200 mg)
• PARGYLINE HYDROCHLORIDE USP/EP/BP
• PARGYLINE HYDROCHLORIDE
• pargylinechloride
• benzyl-methyl-propargyl-amine hydrochloride
• N-Methyl-N-(2-propynyl)benzylamine hydrochloride, N-Methyl-N-propargylbenzylamine hydrochloride
• Pargyline hydrochloride,N-Methyl-N-(2-propynyl)benzylamine hydrochloride, N-Methyl-N-propargylbenzylamine hydrochloride
• Pargylamine hydrochloride

Pargyline Hydrochloride

CAS: 306-07-0

Forma y color: Neat

Ref: 61-FOR1912.00

Pargyline, HCl

CAS: 306-07-0

Fórmula: C₁₁H₁₄ClN

Pureza: 97%

Forma y color: Solid

Peso molecular: 195.6886

Ref: IN-DA0030N6

Pargyline hydrochloride

CAS: 306-07-0

Pargyline hydrochloride (Pargylamine hydrochloride) is an irreversible monoamine oxidase(MAO) inhibitor with antihypertensive properties.

Fórmula: C₁₁H₁₄ClN

Pureza: 99.41% - 99.91%

Forma y color: Solid

Peso molecular: 195.69

Ref: TM-T1578

Pargyline hydrochloride

CAS: 306-07-0

Pargyline hydrochloride

Pureza: ≥98%

Peso molecular: 195.69g/mol

Ref: 54-BUP17536

Pargyline hydrochloride

CAS: 306-07-0

Pargyline hydrochloride

Pureza: 98%

Forma y color: Solid

Peso molecular: 195.69g/mol

Ref: 54-OR54425

Pargyline hydrochloride

CAS: 306-07-0

Fórmula: C₁₁H₁₃N·HCl

Pureza: ≥ 98.0%

Forma y color: White to off-white crystalline powder

Peso molecular: 195.69

Ref: 7W-GP7491

Pargyline Hydrochloride

Producto controlado

CAS: 306-07-0

Fórmula: C₁₁H₁₃N·ClH

Forma y color: Neat

Peso molecular: 195.69

Ref: 86-MM1912.00

Pargyline Hydrochloride

Producto controlado

CAS: 306-07-0

Applications Pargyline Hydrochloride acts as a monoamine oxidase (MAO) inhibitor, decreasing systolic blood pressure steadily in subjects. Antihypertensive. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Fuentes, J. et al.: Eur. J. Pharm., 57, 21 (1979); Knoll, J. et al.: Tabei, R. et al.: Clin. Pharm. Ther., 11, 269 (1970);

Fórmula: C₁₁H₁₃N·ClH

Forma y color: Neat

Peso molecular: 195.69

Ref: TR-P193285

N-Benzyl-N-methylprop-2-yn-1-amine hydrochloride

CAS: 306-07-0

Fórmula: C₁₁H₁₄ClN

Pureza: 97%

Forma y color: Solid

Peso molecular: 195.69

Ref: 10-F336074

N-Methyl-N-propargylbenzylamine HCl

Producto controlado

CAS: 306-07-0

N-Methyl-N-propargylbenzylamine HCl is a nonsteroidal anti-inflammatory drug that inhibits the enzyme cyclooxygenase (COX) and blocks the production of prostaglandins. This drug has low potency, although its selectivity for COX-2 makes it an attractive candidate for treatment of inflammation associated with arthritis. N-Methyl-N-propargylbenzylamine HCl also has been shown to have receptor activity on toll-like receptor 4 in human biological samples. It has been shown to decrease dopamine levels in rats, suggesting that it may be a potential treatment for Parkinson's disease. In addition, this drug was found to decrease epithelial mesenchymal transition and increase expression of p53 protein in prostate cancer cells, as well as inhibit 5HT2 receptors in rat brain tissue. This drug also increases 5HT concentrations and decreases diastolic blood pressure in humans.

Pureza: Min. 95%

Ref: 3D-FM41823