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CAS 3063042-81-6

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  • (R)-STU104-d6
    Targetmol
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    (R)-STU104-d6

    CAS:
    <p>(R)-STU104-d6 is a deuterium-labeled variant of (R)-STU104. This compound acts as a potent and orally active inhibitor of the interaction between TAK1 and MKK3 proteins, exhibiting IC50 values of 0.58 μM for TNF-α and 4.0 μM for MKK3 phosphorylation. By binding to MKK3, (R)-STU104 hinders TAK1's ability to phosphorylate MKK3, thereby disrupting the TAK1/MKK3/p38/MnK1/MK2/elF4E signaling pathway. It is utilized in research related to ulcerative colitis.</p>
    Fórmula:C18H182D6O4
    Forma y color:Solid
    Peso molecular:304.37

    Ref: TM-T207425