CAS 31282-04-9
:Higromicina B
Descripción:
Higromicina B es un antibiótico aminoglucósido producido por la bacteria *Micromonospora hygroscopicus*. Es conocido principalmente por su capacidad para inhibir la síntesis de proteínas en bacterias y algunas células eucariotas, lo que lo convierte en una herramienta valiosa en biología molecular para seleccionar organismos genéticamente modificados. Higromicina B es efectivo contra un amplio espectro de microorganismos, incluyendo ciertas bacterias Gram-positivas y Gram-negativas, así como hongos. Su mecanismo de acción implica la unión al ARN ribosómico, interrumpiendo el proceso de traducción. El compuesto se utiliza típicamente en entornos de laboratorio para la selección de células que han sido transformadas con genes de resistencia a la higromicina. Higromicina B es soluble en agua y exhibe estabilidad bajo diversas condiciones de pH, aunque es sensible a la luz y debe almacenarse en un ambiente oscuro. Se requieren precauciones de seguridad al manipular este compuesto, ya que puede ser tóxico para los humanos y otros organismos a altas concentraciones. En general, Higromicina B es un reactivo crucial en la ingeniería genética y la investigación en biología celular.
Fórmula:C20H37N3O13
InChI:InChI=1S/C20H37N3O13/c1-23-7-2-5(21)9(26)15(10(7)27)33-19-17-16(11(28)8(4-25)32-19)35-20(36-17)18(31)13(30)12(29)14(34-20)6(22)3-24/h5-19,23-31H,2-4,21-22H2,1H3/t5-,6+,7+,8-,9+,10-,11+,12-,13+,14-,15-,16+,17+,18-,19+,20?/m1/s1
Clave InChI:InChIKey=GRRNUXAQVGOGFE-HUCHGKBZSA-N
SMILES:O[C@H]1C2(O[C@]3([C@@](O2)([C@@H](O)[C@@H](CO)O[C@H]3O[C@H]4[C@H](O)[C@@H](NC)C[C@@H](N)[C@@H]4O)[H])[H])O[C@]([C@H](CO)N)([C@H](O)[C@@H]1O)[H]
Sinónimos:- (3'R,3aS,4S,4'R,5'R,6R,6'R,7S,7aS)-4-{[(1R,2S,3R,5S,6R)-3-amino-2,6-dihydroxy-5-(methylamino)cyclohexyl]oxy}-6'-[(1S)-1-amino-2-hydroxyethyl]-6-(hydroxymethyl)octahydro-4H-spiro[1,3-dioxolo[4,5-c]pyran-2,2'-pyran]-3',4',5',7-tetrol (non-preferred name)
- <span class="text-smallcaps">D</smallcap>-Streptamine, O-6-amino-6-deoxy-<smallcap>L</smallcap>-glycero-<smallcap>D</smallcap>-galacto-heptopyranosylidene-(1→2-3)-O-β-<smallcap>D</span>-talopyranosyl-(1→5)-2-deoxy-N<sup>3</sup>-methyl-
- Antihelmycin
- Hygromix 2.4
- Hygromix-8
- Hygromycin B
- Hygromycin B - Solution
- Hygromycin B Streptomyces hygroscopicus
- Hygromycin B solution Streptomyces hygroscopicus
- Hygrovetin
- Hygrovetine
- O-6-Amino-6-deoxy-<span class="text-smallcaps">L</smallcap>-glycero-<smallcap>D</smallcap>-galacto-heptopyranosylidene-(1→2-3)-O-β-<smallcap>D</smallcap>-talopyranosyl-(1→5)-2-deoxy-N<sup>3</sup>-methyl-<smallcap>D</span>-streptamine
- hygromycin B aqueous solution
- hygromycin B from streptomyces*hygroscopicus
- hygromycin B plant cell culture tested
- D-Streptamine, O-6-amino-6-deoxy-L-glycero-D-galacto-heptopyranosylidene-(1→2-3)-O-β-D-talopyranosyl-(1→5)-2-deoxy-N3-methyl-
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Encontrado 18 productos.
Hygromycin B
CAS:Fórmula:C20H37N3O13Pureza:>80.0%(HPLC)Forma y color:White to Light yellow to Light orange powder to crystalPeso molecular:527.52Hygromycin B
CAS:<p>Hygromycin B, 31282-04-9, is an aminoglycoside antibiotic which exhibits activity against eukaryotic and prokaryotic cells through inhibition of protein synthesis. Learn more.</p>Fórmula:C20H37N3O13Forma y color:Cream to plale brown, PowderPeso molecular:527.52Hygromycin B, 50 mg/ml in distilled water, sterile-filtered
CAS:<p>Hygromycin B, 50mg/mL in distilled water, sterile-filtered</p>Fórmula:C20H37N3O13Forma y color:Liquid, Pale yellow to brownPeso molecular:527.52Hygromycin B
CAS:Hygromycin B disrupts protein synthesis in 70S ribosomes, used as an anthelmintic in swine.Fórmula:C20H37N3O13Pureza:98% - 99.78%Forma y color:solidPeso molecular:527.52Hygromycin B
CAS:Fórmula:C20H37N3O13Pureza:≥ 90.0%Forma y color:White to beige powderPeso molecular:527.53Hygromycin B, PBS solution
CAS:Hygromycin B, PBS solutionFórmula:C20H37N3O13Pureza:(hplc) min. 90.0% 91.5% (Typical Value in Batch COA)Forma y color:LiquidPeso molecular:527.52g/molHygromycin B, powder
CAS:Hygromycin B, powderFórmula:C20H37N3O13Pureza:By hplc: 99.4% (Typical Value in Batch COA)Forma y color: light tan powderPeso molecular:527.52g/molHygromycin B Deuterated (d4 major)
CAS:Producto controladoFórmula:C20H33D4N3O13Forma y color:NeatPeso molecular:531.54Hygromycin B
CAS:<p>Hygromycin B binds near the A site of 16S rRNA and induces errors in the code by inhibition of translocation of peptydil-tRNA, however to a lesser extent compared to other aminoglycosides. Hygromycin B is efficient against bacteria, fungi and other eukaryotic cells, but more often used for the selection of eukaryotic cells including yeasts, such as, P. pastoris and S. cerevisiae, and mammalian cell lines, such as, CHO.</p>Fórmula:C20H37N3O13Pureza:Min. 95%Forma y color:White PowderPeso molecular:527.52 g/molHygromycin B - min 90%
CAS:<p>Inhibitor of protein synthesis; aminoglycoside</p>Fórmula:C20H37N3O13Pureza:Min. 90 Area-%Forma y color:PowderPeso molecular:527.52 g/molHygromycin B
CAS:Producto controlado<p>Applications Hygromycin B is an aminoglycoside and a selective antibiotic agent for the hph gene. Hygromycin B inhibits protein synthesis by interfering with translocation and causing mistranslation at the 70S ribosome<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cha, T.S., et al.: World. J. Microbiol. Biotechnol., 28, 1771 (2012); Herrero, L., et al.: Biochem., 52, 171 (2013);<br></p>Fórmula:C20H37N3O13Forma y color:Off-WhitePeso molecular:527.52Hygromycin B (HGR), 90%
CAS:Fórmula:C20H37N3O13Pureza:min. 90%Forma y color:White to off - white, PowderPeso molecular:527.52Hygromycin B (HGR) for tissue culture, 90%
CAS:Fórmula:C20H37N3O13Pureza:min. 90%Forma y color:White to off white, PowderPeso molecular:527.52Hygromycin B (HGR Solution), 50mg/ml in Aq. Solution
CAS:Fórmula:C20H37N3O13Forma y color:Light yellow to very dark yellow to brown-yellow or light orange to very dark orange, Liquid, Clear to slight hazyPeso molecular:527.52
