CAS 32233-40-2

(3aR,4S,5R,6aS)-Hexahidro-5-hidroxi-4-(hidroximetil)-2H-ciclopenta[b]furano-2-ona

Descripción:

La sustancia química conocida como (3aR,4S,5R,6aS)-Hexahidro-5-hidroxi-4-(hidroximetil)-2H-ciclopenta[b]furano-2-ona, con el número CAS 32233-40-2, es un compuesto bicíclico caracterizado por su estructura de anillo fusionado única. Este compuesto presenta múltiples estereocentros, que contribuyen a su configuración tridimensional específica y pueden influir en su actividad biológica. La presencia de grupos hidroxilo (-OH) indica que puede exhibir características polares, mejorando su solubilidad en agua y su reactividad en varias reacciones químicas. La parte de furanona sugiere que puede participar en reacciones típicas de lactonas y éteres cíclicos, lo que lo hace de interés en la síntesis orgánica y la química medicinal. Además, la estereoquímica del compuesto puede desempeñar un papel crucial en su interacción con objetivos biológicos, lo que podría ser relevante para aplicaciones farmacológicas. En general, las características estructurales de este compuesto sugieren una utilidad potencial en varios campos, incluida el desarrollo de fármacos y la ciencia de materiales, aunque las aplicaciones específicas dependerían de investigaciones y caracterizaciones adicionales.

Fórmula: C₈H₁₂O₄

InChI: InChI=1/C8H12O4/c9-3-5-4-1-8(11)12-7(4)2-6(5)10/h4-7,9-10H,1-3H2/t4-,5-,6-,7+/m1/s1

Clave InChI: InChIKey=VYTZWRCSPHQSFX-GBNDHIKLSA-N

SMILES: C(O)[C@@H]1[C@@]2([C@](C[C@H]1O)(OC(=O)C2)[H])[H]

Sinónimos:

• (-)-6beta-Hydroxymethyl-7alpha-hydroxy-cis-2-oxabicyclo[3.3.0]octan-3-one
• (-)-Corey's lactone diol
• (-)-Coreydiol
• (3aR,4S,5R,6aS)-(-)-Hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one
• (3aR,4S,5R,6aS)-5-hydroxy-4-(hydroxymethyl)hexahydro-2H-cyclopenta[b]furan-2-one
• 2H-Cyclopenta[b]furan-2-one, hexahydro-5-hydroxy-4-(hydroxymethyl)-, [3aR-(3aα,4α,5β,6aα)]-
• 2H-Cyclopenta[b]furan-2-one, hexahydro-5-hydroxy-4-(hydroxymethyl)-, stereoisomer
• 2H-Cyclopenta[b]furan-2-one,hexahydro-5-hydroxy-4-(hydroxymethyl)-,(3aR,4S,5R,6aS)-
• Lactone diol
• (-)-Corey Lactone Diol
• (1R)-2β-(Hydroxymethyl)-3α,5α-dihydroxycyclopentane-1α-acetic acid 1,5-lactone
• (-)-COREY DIOL (COREY LACTONE)
• (1S,5R,6S,7R)-7-Hydroxy-6-hydroxymethyl-2-oxabicyclo[3.3.0]octan-3-one
• (3AR,4S,5R,6AS)-(-)-HEXAHYDRO-5-HYDROXY-4--2H-CYCLOPENTA(B)FURAN-2-ONE,
• (3aβ,4S,6aβ)-4β-(Hydroxymethyl)-5α-hydroxyhexahydro-2H-cyclopenta[b]furan-2-one
• (3AR,4S,5R,6AS)-(-)-HEXAHYDRO-5-HYDROXY-4-(HYDROXYMETHYL)-2H-CYCLOPENT A[B]FURAN-2-ONE
• Hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one.
• (3AR,4S,5R,6AS)-(-)-HEXAHYDRO-5-HYDROXY-4-HOCH2-2H-CYCLOPENTA(B)FURAN-2-ONE, 98%
• (-)-COREY LACTONE

(3aR,4S,5R,6aS)-(-)-Hexahydro-5-hydroxy-4-hydroxymethyl-2H-cyclopenta[b]furan-2-one, 98%

CAS: 32233-40-2

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₈H₁₂O₄

Pureza: 98%

Peso molecular: 172.18

Ref: 02-H56119

(3aR,4S,5R,6aS)-5-Hydroxy-4-(hydroxymethyl)hexahydro-2H-cyclopenta[b]furan-2-one

CAS: 32233-40-2

Fórmula: C₈H₁₂O₄

Pureza: 97%

Forma y color: Solid

Peso molecular: 172.1785

Ref: IN-DA0032AQ

(1S,5R,6S,7R)-(-)-7-Hydroxy-6-(hydroxymethyl)-2-oxabicyclo[3.3.0]octan-3-one

CAS: 32233-40-2

(1S,5R,6S,7R)-(-)-7-Hydroxy-6-(hydroxymethyl)-2-oxabicyclo[3.3.0]octan-3-one

Pureza: 99%

Forma y color: Solid

Peso molecular: 172.18g/mol

Ref: 54-OR52144

(-)-Corey lactone diol

CAS: 32233-40-2

(-)-Corey lactone diol

Pureza: ≥95%

Peso molecular: 172.18g/mol

Ref: 54-BUP18578

(-)-Corey Lactone Diol

CAS: 32233-40-2

Fórmula: C₈H₁₂O₄

Pureza: >98.0%(GC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 172.18

Ref: 3B-H1418

(-)-Corey lactone diol

CAS: 32233-40-2

(-)-Corey lactone diol is a pharmaceutical intermediate

Fórmula: C₈H₁₂O₄

Pureza: 98%

Forma y color: White To Beige-Brown Cryst Powder Or Crystals

Peso molecular: 172.18

Ref: TM-T8085

(3aR,4S,5R,6aS)-5-Hydroxy-4-(hydroxymethyl)hexahydro-2H-cyclopenta[b]furan-2-one

CAS: 32233-40-2

Fórmula: C₈H₁₂O₄

Pureza: 97%

Forma y color: Solid

Peso molecular: 172.18

Ref: 10-F239043

(-)-Corey Lactone Diol

Producto controlado

CAS: 32233-40-2

Applications (-)-Corey Lactone Diol is an intermediate of Iloprost (I267300) and shows inhibitory activity towards β-lactamase. Iloprost (I267300) is a synthetic analogue of Prostacyclin (PGI2) used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud's phenomenon and ischemia.
References Gal, Z. et al.: J. Chemother., 12, 274 (2000); Zamudio, T.P.: Arch. Cardiol. Mex., 77, 198 (2007); Lai, Y. et al.: Am. J. Resp. Crit. Care Med., 178, 188 (2008);

Fórmula: C₈H₁₂O₄

Forma y color: Neat

Peso molecular: 172.18

Ref: TR-C694995

(-)-Corey lactone diol

CAS: 32233-40-2

(-)-Corey lactone diol is a synthetic compound that is soluble in organic solvents. It is used for the synthesis of carbocyclic nucleosides, which are analogs of pyrimidine nucleosides. (-)-Corey lactone diol has been shown to inhibit cholesterol synthesis and the synthesis of alkene. (-)-Corey lactone diol also shows anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis.

Fórmula: C₈H₁₂O₄

Pureza: Min. 95%

Peso molecular: 172.18 g/mol

Ref: 3D-FC29747