CAS 32887-01-7

Mecilinamo

Descripción:

Mecilinamo es un antibiótico beta-lactámico que pertenece a la clase de las penicilinas, diseñado específicamente para atacar e inhibir la síntesis de la pared celular bacteriana. Es particularmente efectivo contra ciertas bacterias Gram-negativas, incluyendo cepas de Escherichia coli y Proteus mirabilis. Mecilinamo funciona al unirse a las proteínas de unión a penicilina (PBPs), que son esenciales para el entrecruzamiento de las capas de peptidoglicano en las paredes celulares bacterianas, lo que finalmente conduce a la lisis celular y la muerte. Este antibiótico se caracteriza por su toxicidad relativamente baja para las células humanas, lo que lo convierte en una opción adecuada para tratar infecciones del tracto urinario y otras infecciones bacterianas. Mecilinamo se administra a menudo por vía oral y es conocido por su estabilidad en presencia de ciertas beta-lactamasas, aunque puede ser susceptible a otras. Sus propiedades farmacocinéticas incluyen una buena absorción y distribución en el cuerpo, siendo la excreción renal una ruta principal de eliminación. En general, Mecilinamo representa un valioso agente terapéutico en el arsenal contra infecciones bacterianas, particularmente aquellas causadas por cepas resistentes.

Fórmula: C₁₅H₂₃N₃O₃S

InChI: InChI=1S/C15H23N3O3S/c1-15(2)11(14(20)21)18-12(19)10(13(18)22-15)16-9-17-7-5-3-4-6-8-17/h9-11,13H,3-8H2,1-2H3,(H,20,21)/t10-,11+,13-/m1/s1

Clave InChI: InChIKey=BWWVAEOLVKTZFQ-NTZNESFSSA-N

SMILES: C(O)(=O)[C@@H]1N2[C@@]([C@H](N=CN3CCCCCC3)C2=O)(SC1(C)C)[H]

Sinónimos:

• (2S,5R,6R)-6-[(azepan-1-ylmethylidene)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• (2S,5R,6R)-6-[[(Hexahydro-1H-azepin-1-yl)methylene]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• (2S,5R,6R)-6-{[(E)-azepan-1-ylmethylidene]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(hexahydro-1H-azepin-1-yl)methylene]amino]-3,3-dimethyl-7-oxo-, (+)-
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(hexahydro-1H-azepin-1-yl)methylene]amino]-3,3-dimethyl-7-oxo-, (2S,5R,6R)-
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(hexahydro-1H-azepin-1-yl)methylene]amino]-3,3-dimethyl-7-oxo-, [2S-(2α,5α,6β)]-
• 6-[[(Hexahydro-1H-azepin-1-yl)methylene]amino]penicillanic acid
• 6-[β-(Hexahydro-1H-azepin-1-yl)methylenamino]penicillanic acid
• 6β-[(Hexahydro-1H-azepin-1-yl)methyleneamino]penicillanic acid
• Amdinocillin
• Coactin
• Fl 1060
• Hexacillin
• Hexapen
• Mecilinamo
• Penicillin Hx
• [(2,2-dimethylpropanoyl)oxy]methyl (5R,6R)-6-{[(E)-azepan-1-ylmethylidene]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

Mecillinam, 90+%

CAS: 32887-01-7

Effective against gram negative bacteria

Fórmula: C₁₅H₂₃N₃O₃S

Pureza: 90+%

Forma y color: Powder, White to off-white

Peso molecular: 325.43

Ref: 02-J66774

(2S,5R,6R)-6-(azepan-1-ylmethylideneamino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

CAS: 32887-01-7

Fórmula: C₁₅H₂₃N₃O₃S

Forma y color: Solid

Peso molecular: 325.4264

Ref: IN-DA00JKJ5

Mecillinam

CAS: 32887-01-7

Mecillinam

Pureza: ≥95%

Peso molecular: 325.43g/mol

Ref: 54-BUP11179

Mecillinam

CAS: 32887-01-7

Fórmula: C₁₅H₂₃N₃O₃S

Pureza: ≥ 95%

Forma y color: White crystalline powder

Peso molecular: 325.43

Ref: 7W-GA6807

Mecillinam-d12

CAS: 32887-01-7

Fórmula: C₁₅H₁₁D₁₂N₃O₃S

Forma y color: Pale Yellow Solid

Peso molecular: 337.50

Ref: 4Z-M-156002

Mecillinam

CAS: 32887-01-7

Fórmula: C₁₅H₂₃N₃O₃S

Peso molecular: 325.43

Ref: 4Z-M-156001

Mecillinam

CAS: 32887-01-7

Mecillinam, an antibiotic, targets Gram-negative bacteria, mainly for urinary infections and some fevers.

Fórmula: C₁₅H₂₃N₃O₃S

Pureza: 95.53% - ≥95%

Forma y color: Solid

Peso molecular: 325.43

Ref: TM-T21369

Amdinocillin (>85%)

Producto controlado

CAS: 32887-01-7

Fórmula: C₁₅H₂₃N₃O₃S

Pureza: ~85%

Forma y color: Neat

Peso molecular: 325.43

Ref: TR-A576405

Amdinocillin

CAS: 32887-01-7

Amdinocillin is a semisynthetic antibiotic with broad-spectrum activity that is part of the aminopenicillin family. It is used in the treatment of bacterial infections such as those caused by Gram-negative bacteria, and to treat methicillin-resistant Staphylococcus (MRSA). The clinical isolate Amdinocillin has an inhibitory concentration (IC) of 0.25 μg/mL against Enterobacter aerogenes and Enterobacter cloacae, and it displays a synergistic effect in combination with other antibiotics. The mechanism of action is that prevents bacterial growth and proliferation by inhibiting cell wall synthesis and causing lysis, which allows for drug therapy against specific types of bacteria.

Fórmula: C₁₅H₂₃N₃O₃S

Pureza: (%) Min. 97%

Forma y color: White Slightly Yellow Powder

Peso molecular: 325.43 g/mol

Ref: 3D-AA17347

Mecillinam (MCL) extrapure, 95%

CAS: 32887-01-7

Fórmula: C₁₅H₂₃N₃O₃S

Pureza: min. 95.0%

Forma y color: White to Light yellow to Light beige, Powder

Peso molecular: 325.43

Ref: SR-54474

Amdinocillin

Producto controlado

CAS: 32887-01-7

Applications Active antibacterial against gram-negative bacteria.
References Cagnacci, S., et al.: J. Clin. Microbiol., 46, 2605 (2008), Obach, R., et al.: Drug Metab. Disposition, 36, 1385 (2008), Ma, C., et al.: J. Pharm. Biomed. Anal., 47, 677 (2008),

Fórmula: C₁₅H₂₃N₃O₃S

Forma y color: White

Peso molecular: 325.43

Ref: TR-A576300

Mecillinam, Antibiotic for Culture Media Use Only

CAS: 32887-01-7

Mecillinam is a beta-lactam antibiotic specifically designed for use in culture media. It is derived from the amidinopenicillin family, featuring a unique ability to interfere with bacterial cell wall synthesis. Its mode of action involves inhibiting penicillin-binding protein 2 (PBP2), an essential enzyme for cell wall elongation and maintenance in Gram-negative bacteria. This targeted inhibition results in the formation of spherical cells and subsequent cell lysis.

Fórmula: C₁₅H₂₃N₃O₃S

Pureza: Min. 95 Area-%

Peso molecular: 325.43 g/mol

Ref: 3D-Q-201343