CAS 32981-85-4

(2R,3S)-N-benzoil-3-fenilisoserina éster metílico

Descripción:

(2R,3S)-N-benzoil-3-fenilisoserina éster metílico es un compuesto químico caracterizado por su estereoequilibrio específico y grupos funcionales. Presenta un grupo bencilo, que es un grupo carbonilo unido a un anillo fenílico, lo que indica su potencial para interacciones típicas de compuestos aromáticos. La presencia de la parte isoserina sugiere que tiene tanto grupos funcionales amino como hidroxilo, lo que contribuye a su potencial solubilidad en disolventes polares. La funcionalidad de éster metílico indica que el grupo ácido carboxílico de la isoserina está esterificado, lo que puede aumentar la lipofilia e influir en su reactividad. Este compuesto puede exhibir actividad biológica debido a su semejanza estructural con aminoácidos, lo que lo hace de interés en la química farmacéutica. Su estereoequilibrio, denotado por la configuración (2R,3S), es crucial para sus interacciones biológicas, ya que la disposición espacial de los átomos puede afectar significativamente las propiedades y el comportamiento del compuesto en sistemas biológicos. En general, la estructura única de este compuesto lo posiciona como una molécula potencialmente valiosa en la química medicinal y campos relacionados.

Fórmula: C₁₇H₁₇NO₄

InChI: InChI=1S/C17H17NO4/c1-22-17(21)15(19)14(12-8-4-2-5-9-12)18-16(20)13-10-6-3-7-11-13/h2-11,14-15,19H,1H3,(H,18,20)/t14-,15+/m0/s1

Clave InChI: InChIKey=UYJLJICUXJPKTB-LSDHHAIUSA-N

SMILES: [C@@H](NC(=O)C1=CC=CC=C1)([C@H](C(OC)=O)O)C2=CC=CC=C2

Sinónimos:

• (2R,3S)-1-benzoyl-2-hydroxy-3-aminophenylpionic acid ester
• (2R,3S)-Methyl 3-benzoylamino-2-hydroxy-3-phenylpropanoate
• (2R,3S)-N-Benzoyl-3-phenylisoserine methyl ester
• Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, methyl ester, (αR,βS)-
• Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, methyl ester, [R-(R*,S*)]-
• Isoserine, N-benzoyl-3-phenyl-, methyl ester, (2R,3S)-
• Lkt-T 0104
• Methyl (-)-(2R,3S)-3-benzoylamino-2-hydroxy-3-phenylpropionate
• Methyl(2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoale
• Methyl(2R,3S)-N-benzoylphenylisoserinate
• Methyl-(2R,3S)-N-Benzoyl-3-Phenylisos
• N-Benzoyl-3-Phenyl isoserine methyl ester
• Paclitaxel Side Chain No.4
• methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate
• methyl (2R,3S)-3-benzamido-2-hydro-3-phenylpropionate

Methyl (2R,3S)-3-benzamido-2-hydroxy-3-phenylpropionate, 98%

CAS: 32981-85-4

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₁₇H₁₇NO₄

Pureza: 98%

Peso molecular: 299.33

Ref: 02-H61641

Benzenepropanoic acid, b-(benzoylamino)-a-hydroxy-, methyl ester,(aR,bS)-

CAS: 32981-85-4

Fórmula: C₁₇H₁₇NO₄

Pureza: 98%

Forma y color: Solid

Peso molecular: 299.3212

Ref: IN-DA00I6BS

Bz-RS-ISer(3-Ph)-Ome

CAS: 32981-85-4

Bz-RS-ISer(3-Ph)-Ome

Pureza: ≥98%

Peso molecular: 299.32g/mol

Ref: 54-BUP17991

(2R,3S)-N-Benzoyl-3-phenylisoserine methyl ester

CAS: 32981-85-4

(2R,3S)-N-Benzoyl-3-phenylisoserine methyl ester

Pureza: 98%

Peso molecular: 299.32g/mol

Ref: 54-OR315016

Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate

CAS: 32981-85-4

Fórmula: C₁₇H₁₇NO₄

Peso molecular: 299.33

Ref: 7W-GY0500

Methyl (2R,3S)-3-Benzamido-2-hydroxy-3-phenylpropanoate

Producto controlado

CAS: 32981-85-4

Fórmula: C₁₇H₁₇NO₄

Forma y color: Neat

Peso molecular: 299.32

Ref: 86-MM1489.09

Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate

CAS: 32981-85-4

Fórmula: C₁₇H₁₇NO₄

Pureza: 95%~99%

Peso molecular: 299.326

Ref: BP-BP4346

Bz-RS-ISer(3-Ph)-Ome

CAS: 32981-85-4

Bz-RS-ISer(3-Ph)-Ome (Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate) is a paclitaxel derivative that inhibits the HSV replication cycle.

Fórmula: C₁₇H₁₇NO₄

Pureza: 99.36% - 99.89%

Forma y color: White Crystal

Peso molecular: 299.32

Ref: TM-T7055

Paclitaxel Impurity 11

CAS: 32981-85-4

Fórmula: C₁₇H₁₇NO₄

Peso molecular: 299.33

Ref: 4Z-P-2850

(2R,3S)-N-Benzoyl-3-phenyl Isoserine Methyl Ester

Producto controlado

CAS: 32981-85-4

Applications (2R,3S)-N-Benzoyl-3-phenyl Isoserine Methyl Ester is an intermediate in the preparation of potent anticancer drug Paclitaxel (P132500) used to study the location of the binding sites.
References Paal, K. et al.: Bioorg. Med. Chem., 15, 1323 (2007); Krawczyk, E. et al.: J. Pharm. Pharmacol., 57, 791 (2005);

Fórmula: C₁₇H₁₇NO₄

Forma y color: Off White Powder

Peso molecular: 299.32

Ref: TR-B208560

Methyl (2R,3S)-N-benzoyl-3-phenylisoserine

CAS: 32981-85-4

Methyl (2R,3S)-N-benzoyl-3-phenylisoserine is a potent anticancer drug that inhibits the growth of tumor cells. It has been shown to be effective against breast cancer and prostate cancer cell lines and is currently being tested in clinical trials for its antitumor activity. Methyl (2R,3S)-N-benzoyl-3-phenylisoserine has been shown to induce apoptosis in a number of tumor cell lines and may function by increasing the intracellular level of reactive oxygen species. This drug also binds to microtubules, which are essential for the mitotic spindle assembly checkpoint that prevents cells from entering mitosis until all chromosomes are properly aligned at the metaphase plate.
Methyl (2R,3S)-N-benzoyl-3-phenylisoserine belongs to the group of taxane drugs and was first isolated from Taxus brevif

Fórmula: C₁₇H₁₇NO₄

Pureza: Min. 95%

Forma y color: White/Off-White Solid

Peso molecular: 299.32 g/mol

Ref: 3D-FM32203

(2R,3S)-Methyl 3-benzamido-2-hydroxy-3-phenylpropanoate

CAS: 32981-85-4

Fórmula: C₁₇H₁₇NO₄

Pureza: ≥98%

Peso molecular: 299.326

Ref: 10-F213091

Paclitaxel Impurity 54

CAS: 32981-85-4

Fórmula: C₁₇H₁₇NO₄

Peso molecular: 299.33

Ref: ST-EA-CP-P36033