CAS 330784-47-9
:Avanafil
Descripción:
Avanafil es un inhibidor selectivo de la fosfodiesterasa tipo 5 (PDE5) utilizado principalmente para el tratamiento de la disfunción eréctil. Se caracteriza por su inicio de acción rápido, típicamente dentro de 15 a 30 minutos después de la administración, lo que lo convierte en una opción popular entre los pacientes que buscan un alivio rápido. La estructura química de Avanafil incluye un núcleo de pirazolo[3,4-d]pirimidina, que contribuye a su actividad farmacológica. Tiene una alta afinidad por la enzima PDE5, lo que lleva a niveles aumentados de monofosfato de guanosina cíclico (cGMP) en el cuerpo cavernoso, facilitando la erección peneana en respuesta a la estimulación sexual. Avanafil generalmente es bien tolerado, con un perfil de efectos secundarios que puede incluir dolores de cabeza, enrojecimiento, congestión nasal y dolor de espalda. Es importante señalar que Avanafil no debe usarse en conjunto con nitratos debido al riesgo de hipotensión significativa. Al igual que con cualquier medicamento, es esencial que los pacientes consulten a profesionales de la salud para un uso adecuado y posibles interacciones.
Fórmula:C23H26ClN7O3
InChI:InChI=1S/C23H26ClN7O3/c1-34-19-6-5-15(10-18(19)24)11-27-21-17(22(33)28-13-20-25-7-3-8-26-20)12-29-23(30-21)31-9-2-4-16(31)14-32/h3,5-8,10,12,16,32H,2,4,9,11,13-14H2,1H3,(H,28,33)(H,27,29,30)/t16-/m0/s1
Clave InChI:InChIKey=WEAJZXNPAWBCOA-INIZCTEOSA-N
SMILES:C(O)[C@H]1N(C=2N=C(NCC3=CC(Cl)=C(OC)C=C3)C(C(NCC=4N=CC=CN4)=O)=CN2)CCC1
Sinónimos:- (S)-2-(2-Hydroxymethyl-1-pyrrolidinyl)-4-(3-chloro-4-methoxybenzylamino)-5-[(2-pyrimidinylmethyl)carbamoyl]pyrimidine
- (S)-2-(2-Hydroxymethyl-1-pyrrolidinyl)-4-(3-chloro-4-methoxybenzylamino)-5-[N-(2-pyrimidinylmethyl)carbamoyl]pyrimidine
- (S)-4-[(3-Chloro-4-methoxybenzyl)amino]-2-[2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)-5-pyrimidinecarboxamide
- 4-[(3-Chloro-4-methoxybenzyl)amino]-2-[2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)-5-pyrimidinecarboxamide
- 4-[(3-chloro-4-methoxybenzyl)amino]-2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide
- 4-[[(3-Chloro-4-methoxyphenyl)methyl]amino]-2-[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)-5-pyrimidinecarboxamide
- 5-Pyrimidinecarboxamide, 4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-2-[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)-
- Spedra
- Ta 1790
- Avanafil
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Encontrado 20 productos.
(S)-2-(2-Hydroxymethyl-1-pyrrolidinyl)-4-(3-chloro-4-methoxybenzylamino)-5-[(2-pyrimidinylmethyl)carbamoyl]pyrimidine
CAS:Fórmula:C23H26ClN7O3Pureza:98%Forma y color:SolidPeso molecular:483.9506Ref: IN-DA0034HA
1g35,00€5g73,00€10g111,00€15g157,00€25g177,00€50g325,00€100g701,00€250gA consultar100mg24,00€250mg25,00€4-[(3-Chloro-4-methoxybenzyl)amino]-2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide
CAS:4-[(3-Chloro-4-methoxybenzyl)amino]-2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamidePureza:98%Peso molecular:483.95064g/molAvanafil 100 µg/mL in Acetonitrile:Dimethylsulfoxide
CAS:Fórmula:C23H26ClN7O3Forma y color:Single SolutionPeso molecular:483.95Avanafil
CAS:Fórmula:C23H26ClN7O3Pureza:>98.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:483.96Avanafil
CAS:Avanafil (TA1790) is a selective inhibitor of phosphodiesterase type 5 (PDE5) and is used as therapy of erectile dysfunction.Fórmula:C23H26ClN7O3Pureza:99.03% - >99.99%Forma y color:White SolidPeso molecular:483.95Avanafil
CAS:Fórmula:C23H26ClN7O3Pureza:≥ 98.0% (dried basis)Forma y color:White to off-white crystalline powderPeso molecular:483.95Avanafil
CAS:Producto controlado<p>Applications A phosphodiesterase (PDE5) inhibitor, used to treat erectile dysfunction.<br>References Hatzimouratidis, K., et al.: Drugs, 68, 231 (2008);<br></p>Fórmula:C23H26ClN7O3Forma y color:WhitePeso molecular:483.95Avanafil - Bio-X ™
CAS:Avanafil is a phosphodiesterase-5 (PDE5) inhibitor drug that can be used as a treatment for male erectile dysfunction. It works by inhibiting the production of PDE5, which is an enzyme that regulates the levels of cGMP in the penis. Elevated levels of cGMP, results in an increase of blood flow to the penis.Fórmula:C23H26ClN7O3Pureza:Min. 95%Forma y color:PowderPeso molecular:483.95 g/molAvanafil
CAS:<p>Avanafil is a drug that can be used as a treatment for male erectile dysfunction. It works by inhibiting the production of PDE5, which is an enzyme that regulates the levels of cGMP in the penis. Avanafil has been shown to be effective when taken at a dose of 100 mg; this is because it takes about 30 minutes for avanafil to reach its peak level. Avanafil has a chemical stability that is greater than 12 hours, with an average lifespan of 24 hours. The drug also has no major drug interactions and does not inhibit any other drugs from working.</p>Fórmula:C23H26ClN7O3Pureza:Min. 98 Area-%Forma y color:White PowderPeso molecular:483.95 g/molAvanafil-13C-d3
CAS:Producto controladoFórmula:CC23D3H25ClN7O2Forma y color:NeatPeso molecular:485.989Avanafil-d5
CAS:Producto controlado<p>Applications Unlabeled compound, Avanafil (A794670), is a phosphodiesterase (PDE5) inhibitor, used to treat erectile dysfunction.<br>References Hatzimouratidis, K., et al.: Drugs, 68, 231 (2008);<br></p>Fórmula:C23H21D5ClN7O3Forma y color:NeatPeso molecular:488.98
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