CAS 330936-69-1

L-Alanina, L-metionil-L-alanil-L-prolil-L-arginilglicil-L-fenilalanil-L-seril-L-cisteinil-L-leucil-L-leucil-L-leucil-L-leucil-L-treonil-L-seril-L-a-glutamil-L-isoleucil-L-a-aspartil-L-leucil-L-prolil-L-valil-L-lisil-L-arginil-L-arginil-

Descripción:

La sustancia química a la que te refieres, con el nombre "L-Alanina, L-metionil-L-alanil-L-prolil-L-arginilglicina-L-fenilalanina-L-serina-L-cisteína-L-leucina-L-leucina-L-leucina-L-leucina-L-treonina-L-serina-L-a-glutamato-L-isoleucina-L-a-aspartato-L-leucina-L-prolina-L-valina-L-lisina-L-arginina-L-arginina-" y número CAS 330936-69-1, es un péptido complejo compuesto de múltiples aminoácidos. Esta sustancia se caracteriza por su secuencia de L-aminoácidos, que son los bloques de construcción de las proteínas. La presencia de varios aminoácidos sugiere una posible actividad biológica, posiblemente relacionada con la síntesis de proteínas o vías de señalización. La disposición específica de estos aminoácidos puede influir en la conformación del péptido, su estabilidad y sus interacciones con otras biomoléculas. Además, la presencia de aminoácidos que contienen azufre como la metionina y la cisteína puede contribuir a la formación de enlaces disulfuro, mejorando la integridad estructural. En general, las características de este péptido estarían determinadas por su secuencia, peso molecular, solubilidad y funciones biológicas potenciales, lo que lo hace de interés en la investigación bioquímica y farmacéutica.

Fórmula: C₁₁₉H₂₀₄N₃₄O₃₂S₂

Sinónimos:

• 1-24-Proteinhumanin (human)
• 188: PN: US20090053203 SEQID: 188 claimed protein
• 1: PN: JP2006213632SEQID: 1 claimed protein
• 1:PN: WO2009040017 PAGE: 98 claimed protein
• 2: PN: WO03045988 SEQID: 2 claimedsequence
• 317: PN:WO2005051988 SEQID: 317 claimed protein
• 369: PN: WO0176532 SEQID: 91 claimedprotein
• 48: PN: WO0181361 SEQID: 47 claimed protein
• 4: PN: WO2008115525 SEQID: 188claimed protein
• 60: PN:WO2008058016 SEQID: 60 claimed protein
• 7: PN: WO0121786 SEQID: 5 claimedsequence
• Humanin
• Humanin(human clone CG202524-01)
• Protein (human clone 1 humanin sequence homolog)
• Protein Humanin (human)
• T lymphocyte activation-associated protein PRO86272(human)
• Humanin Trifluoroacetate
• 1: PN: US20060100253 SEQID: 1 unclaimed sequence
• Humanin (human)
• 3: PN: WO03106683 SEQID: 3 claimed sequence
• 5: PN: WO0121787 SEQID: 5 claimed sequence
• 40: PN: WO2004047728SEQID: 7249 claimed sequence
• 4:PN: WO2006019365 SEQID: 4 claimed sequence
• 2: PN: WO2009117596 SEQID: 1 unclaimed sequence
• 7: PN: WO2009135165 SEQID: 14 unclaimed sequence
• H-MET-ALA-PRO-ARG-GLY-PHE-SER-CYS-LEU-LEU-LEU-LEU-THR-SER-GLU-ILE-ASP-LEU-PRO-VAL-LYS-ARG-ARG-ALA-OH
• Leucostoma persoonii (Nitschke) H&ouml
• MAPRGFSCLLLLTSEIDLPVKRRA
• L-Alanine, L-methionyl-L-alanyl-L-prolyl-L-arginylglycyl-L-phenylalanyl-L-seryl-L-cysteinyl-L-leucyl-L-leucyl-L-leucyl-L-leucyl-L-threonyl-L-seryl-L- alpha-glutamyl-L-isoleucyl-L-alpha-aspartyl-L-leucyl-L-prolyl-L-valyl-L-lysyl-L-arginyl-L-arginyl-
• MET-ALA-PRO-ARG-GLY-PHE-SER-CYS-LEU-LEU-LEU-LEU-THR-SER-GLU-ILE-ASP-LEU-PRO-VAL-LYS-ARG-ARG-ALA TRIFLUOROACETATE
• 1-24-Protein humanin (human)
• H-MAPRGFSCLLLLTSEIDLPVKRRA-OH
• Humanin, HN
• MET-ALA-PRO-ARG-GLY-PHE-SER-CYS-LEU-LEU-LEU-LEU-THR-SER-GLU-ILE-ASP-LEU-PRO-VAL-LYS-ARG-ARG-ALA
• Humanin (1)
• Drepanopeziza populorum (Desm.) H&ouml
• HNMET-ALA-PRO-ARG-GLY-PHE-SER-CYS-LEU-LEU-LEU-LEU-THR-SER-GLU-ILE-ASP-LEU-PRO-VAL-LYS-ARG-ARG-ALA
• MAPGSGCLLLLTSEIDLPVKRRA
• HN
• Humanin(human)trifluoroacetate
• Humanin S14-G
• Humanin(human) acetate

Humanin, human

CAS: 330936-69-1

For cellular and molecular biology applications

Fórmula: C₁₁₉H₂₀₄N₃₄O₃₂S₂

Peso molecular: 2687.22

Ref: 02-J66525

Humanin (human)

CAS: 330936-69-1

Humanin (HN) is a polypeptide suppressing neuronal cell death induced by several familial Alzheimer’s disease genes and by amyloid β-protein (1-43) (human). It has been shown that amyloid β-protein (1-40) and amyloid β-protein (1-42) secretion is not affected by humanin in F11 cells expressing the familial Alzheimer’s disease gene K595N/M596L-APP. Inhibitory actions on neuronal cell death triggered by K595N/M596L-APP directly and caused by amyloid β-protein have been suggested.

Fórmula: C₁₁₉H₂₀₄N₃₄O₃₂S₂

Pureza: 96.0%

Forma y color: White Whitish Powder

Peso molecular: 2687.27

Ref: 01-4038276

Humanin (human)

CAS: 330936-69-1

Encoded for by mitochondrial DNA, Humanin is an endogenous peptide known to be a ‘rescue factor’ with the ability to abolish neuronal cell death. This characteristic has promoted Humanin as a potential treatment for Alzheimer’s disease. Another function of Humanin is it can inhibit mitochondira-dependent apoptosis through preventing the formation of apoptotic bodies and the release of Cytochrome C.Humanin has been found to be related to aging related cardiovascular disease (ACVDs) due to evidence of Humanin serum levels as age increases. Furthermore Humanin increases the expression of antioxidant defense system proteins and impedes complexes I and III from their activity in the electron transport chain in myocardial cells and mitochondria, therefore decreasing oxidative stress damage caused by H2O2. Humanin further reduces reactive oxygen species production and protects cardiomyocytes and fibroblasts, from oxidative stress.Overall Humanin has a variety of protective functions such as mitochondrial homeostasis and redox systems regulation, anti-aging, prevention of myocardial fibrosis, anti-inflammation, metabolism improvement and autophagy promotion. It has also been found to improve beta-cell survival and thus can be used as a diabetes treatment due to it improving insulin secretion and resistance.

Fórmula: C₁₁₉H₂₀₄N₃₄O₃₂S₂

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 2,687.28 g/mol

Ref: 3D-PH17011

Humanin

CAS: 330936-69-1

Encoded for by mitochondrial DNA, Humanin is an endogenous peptide known to be a ‘rescue factor’ with the ability to abolish neuronal cell death. This characteristic has promoted Humanin as a potential treatment for Alzheimer’s disease. Another function of Humanin is it can inhibit mitochondira-dependent apoptosis through preventing the formation of apoptotic bodies and the release of Cytochrome C.
Humanin has been found to be related to aging related cardiovascular disease (ACVDs) due to evidence of Humanin serum levels as age increases. Furthermore Humanin increases the expression of antioxidant defense system proteins and impedes complexes I and III from their activity in the electron transport chain in myocardial cells and mitochondria, therefore decreasing oxidative stress damage caused by H2O2. Humanin further reduces reactive oxygen species production and protects cardiomyocytes and fibroblasts, from oxidative stress.
Overall Humanin has a variety of protective functions such as mitochondrial homeostasis and redox systems regulation, anti-aging, prevention of myocardial fibrosis, anti-inflammation, metabolism improvement and autophagy promotion. It has also been found to improve beta-cell survival and thus can be used as a diabetes treatment due to it improving insulin secretion and resistance. This product is available as a 0.5mg vial.

Fórmula: C₁₁₉H₂₀₄N₃₄O₃₂S₂

Pureza: Min. 95%

Peso molecular: 2,687.2 g/mol

Ref: 3D-PHN-4384-V