CAS 332943-64-3

VU041

CAS: 332943-64-3

VU041 inhibits mosquito Kir1 channels (IC50: An. gambiae 2.5μM, Ae. aegypti 1.7μM), less on mammalian Kir2.1 (12.7μM), and minimally on other Kir channels.

Fórmula: C₁₉H₂₀F₃N₃O

Pureza: 98%

Forma y color: Solid

Peso molecular: 363.38

Ref: TM-T17240

1-(1,2,3,4-Tetrahydroquinolin-1-yl)-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl]ethan-1-one

CAS: 332943-64-3

1-(1,2,3,4-Tetrahydroquinolin-1-yl)-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl]ethan-1-one (EBQ) is a novel small molecule that has been shown to activate the G protein coupled receptor GPR17. EBQ has also been shown to inhibit the activity of the ion channels TRPV4 and TRPA1 in vitro. EBQ is a potent inhibitor of human CDK5 and may be useful for Alzheimer's disease treatment.

Fórmula: C₁₉H₂₀F₃N₃O

Pureza: Min. 95%

Peso molecular: 363.4 g/mol

Ref: 3D-HNA94364