CAS 33342-05-1

Gliclidona

Descripción:

Gliclidona es un agente hipoglucemiante oral que pertenece a la clase de las sulfonilureas, utilizado principalmente en el manejo de la diabetes mellitus tipo 2. Funciona estimulando la secreción de insulina de las células beta pancreáticas, reduciendo así los niveles de glucosa en sangre. Gliclidona se caracteriza por su estructura química, que incluye un grupo sulfonilurea, contribuyendo a su actividad farmacológica. La sustancia se administra típicamente en forma de tabletas y es conocida por su eficacia moderada en el control glucémico. Su farmacocinética implica la absorción en el tracto gastrointestinal, con concentraciones plasmáticas máximas que ocurren dentro de unas pocas horas después de la administración. Gliclidona se metaboliza en el hígado, y sus metabolitos se excretan principalmente a través de la orina. Los efectos secundarios comunes pueden incluir hipoglucemia, trastornos gastrointestinales y reacciones alérgicas. Al igual que con otras sulfonilureas, es esencial que los pacientes monitoreen regularmente sus niveles de glucosa en sangre y mantengan una dieta equilibrada y un régimen de ejercicio para optimizar los resultados del tratamiento. Se aconseja precaución en pacientes con insuficiencia renal o hepática, ya que estas condiciones pueden afectar el metabolismo y la eliminación del fármaco.

Fórmula: C₂₇H₃₃N₃O₆S

InChI: InChI=1S/C27H33N3O6S/c1-27(2)23-14-11-20(36-3)17-22(23)24(31)30(25(27)32)16-15-18-9-12-21(13-10-18)37(34,35)29-26(33)28-19-7-5-4-6-8-19/h9-14,17,19H,4-8,15-16H2,1-3H3,(H2,28,29,33)

Clave InChI: InChIKey=LLJFMFZYVVLQKT-UHFFFAOYSA-N

SMILES: CC1(C)C=2C(C(=O)N(CCC3=CC=C(S(NC(NC4CCCCC4)=O)(=O)=O)C=C3)C1=O)=CC(OC)=CC2

Sinónimos:

• 1-Cyclohexyl-3-[4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxo-1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl]benzenesulfonyl]urea
• 1-Cyclohexyl-3-[4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxoisoquinolin-2-yl)ethyl]phenyl]sulfonylurea
• 1-Cyclohexyl-3-[[p-[2-(3,4-dihydro-7-methoxy-4,4-dimethyl-1,3-dioxo-2(1H)-isoquinoyl)ethyl]phenyl]sulfonyl]urea
• Ar 3-Ardf 26
• Ar-Df 26
• Ardf 26Se
• Beglynor
• Glichidon
• Gliquidona
• Gliquidone
• Glurenorm
• N-[(Cyclohexylamino)carbonyl]-4-[2-(3,4-dihydro-7-methoxy-4,4-dimethyl-1,3-dioxo-2(1H)-isoquinolinyl)ethyl]benzenesulfonamide
• TangShenPing
• TangShiPing
• Zinc 01482077
• Zinc 1482077

Gliquidone

CAS: 33342-05-1

Fórmula: C₂₇H₃₃N₃O₆S

Pureza: >98.0%(T)(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 527.64

Ref: 3B-G0332

1-cyclohexyl-3-({4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxo-1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl]benzene}sulfonyl)urea

CAS: 33342-05-1

Fórmula: C₂₇H₃₃N₃O₆S

Pureza: 99%

Forma y color: Solid

Peso molecular: 527.6324

Ref: IN-DA0034YT

Gliquidone

CAS: 33342-05-1

Gliquidone (AR-DF 26) is a potent, second-generation sulfonylurea with antihyperglycemic activity.

Fórmula: C₂₇H₃₃N₃O₆S

Pureza: 98.92% - 99.93%

Forma y color: Solid

Peso molecular: 527.63

Ref: TM-T0371

Gliquidone

CAS: 33342-05-1

Gliquidone

Pureza: ≥98%

Peso molecular: 527.63g/mol

Ref: 54-BUP14986

Gliquidone

CAS: 33342-05-1

Fórmula: C₂₇H₃₃N₃O₆S

Forma y color: White To Off-White Solid

Peso molecular: 527.64

Ref: 4Z-G-050001

N-(Cyclohexylcarbamoyl)-4-(2-(7-Methoxy-4,4-Dimethyl-1,3-Dioxo-3,4-Dihydroisoquinolin-2(1H)-Yl)Ethyl)Benzenesulfonamide

CAS: 33342-05-1

N-(Cyclohexylcarbamoyl)-4-(2-(7-Methoxy-4,4-Dimethyl-1,3-Dioxo-3,4-Dihydroisoquinolin-2(1H)-Yl)Ethyl)Benzenesulfonamide

Pureza: 98%

Peso molecular: 527.63g/mol

Ref: 54-OR1029252

Gliquidone

CAS: 33342-05-1

Fórmula: C₂₇H₃₃N₃O₆S

Pureza: ≥ 98.0%

Forma y color: White to off-white or pale yellow crystalline powder

Peso molecular: 527.63

Ref: 7W-GP4220

Gliquidone-d6

CAS: 33342-05-1

Fórmula: C₂₇H₂₇D₆N₃O₆S

Forma y color: White To Off-White Solid

Peso molecular: 533.67

Ref: 4Z-G-050002

Gliquidone

CAS: 33342-05-1

Fórmula: C₂₇H₃₃N₃O₆S

Forma y color: Neat

Peso molecular: 527.63

Ref: 86-MM3094.00

Gliquidone

Producto controlado

CAS: 33342-05-1

Applications Gliquidone is an anti diabetic agent used in the treatment of hypoglycemia which leads to an increased risk in diabetic cardiovascular disease. Also used in the treatment diabetic nephropathy.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Tan, Z. et al.: Chinese Med. J., 127, 1298 (2014); Ke, J, et al.: J. Endocrinol., 220, 129 (2014);

Fórmula: C₂₇H₃₃N₃O₆S

Forma y color: Neat

Peso molecular: 527.63

Ref: TR-G410500

3-Cyclohexyl-1-[4-[2-(7-methoxy -4,4-dimethyl-1,3-dioxo-isoquinolin -2-yl)ethyl]phenyl]sulfonyl-urea

CAS: 33342-05-1

3-Cyclohexyl-1-[4-[2-(7-methoxy -4,4-dimethyl-1,3-dioxo-isoquinolin -2-yl)ethyl]phenyl]sulfonyl-urea is a drug that inhibits the enzyme DPPIV, which breaks down the incretin hormone glucagon-like peptide (GLP)-1. It may be used to treat diabetes by regulating blood glucose levels. This drug has been shown to reduce postprandial blood glucose levels in patients with type 2 diabetes. 3CYCSU is also capable of reducing body weight and food intake in mice. The mechanism of action of this drug is not fully understood, but it appears to have an effect on the cytosolic calcium ion concentration and may reduce inflammatory responses in cells. 3CYCSU is a promising potential treatment for infectious diseases such as Hepatitis C virus (HCV).

Fórmula: C₂₇H₃₃N₃O₆S

Forma y color: Powder

Peso molecular: 527.63 g/mol

Ref: 3D-FG40551

GLIQUIDONE

CAS: 33342-05-1

Pureza: 99%

Peso molecular: 527.6400146

Ref: 10-F828164

Gliquidone

CAS: 33342-05-1

Forma y color: Neat

Ref: 61-FOR3094.00

Gliquidone

CAS: 33342-05-1

Gliquidone

Fórmula: C₂₇H₃₃N₃O₆S

Pureza: 99.7%

Forma y color: White

Peso molecular: 527.20901

Ref: 47-580