CAS 337376-15-5

Icodextrina

Descripción:

Icodextrina es un carbohidrato sintético derivado de la hidrólisis enzimática del almidón, utilizado principalmente en aplicaciones médicas, particularmente en soluciones para diálisis peritoneal. Es un polímero de glucosa compuesto de varias longitudes de cadena, lo que contribuye a sus propiedades únicas. Icodextrina se caracteriza por su capacidad para crear un gradiente osmótico, facilitando la eliminación de exceso de líquido del cuerpo mientras minimiza el riesgo de complicaciones relacionadas con la glucosa. Se presenta típicamente como una solución clara e incolora y es conocido por su biocompatibilidad y baja inmunogenicidad. La sustancia es estable en condiciones normales y tiene un peso molecular relativamente bajo, lo que permite una absorción y excreción eficientes. Además, Icodextrina tiene un bajo valor calórico, lo que lo hace adecuado para pacientes que requieren manejo de líquidos sin una ingesta calórica significativa. Su uso en entornos clínicos se ha asociado con mejores resultados en pacientes en diálisis, particularmente en términos de ultrafiltración y equilibrio de líquidos. En general, Icodextrina representa un avance significativo en el manejo de pacientes que se someten a diálisis peritoneal.

Fórmula: Unspecified

InChI: InChI=1/C46H62N4O11/c1-22(2)21-50-18-16-46(17-19-50)48-34-31-32-39(54)28(8)42-33(31)43(56)45(10,61-42)59-20-15-30(58-11)25(5)41(60-29(9)51)27(7)38(53)26(6)37(52)23(3)13-12-14-24(4)44(57)47-36(40(32)55)35(34)49-46/h12-15,20,22-23,25-27,30,37-38,41,49,52-54H,16-19,21H2,1-11H3,(H,47,57)/b13-12-,20-15-,24-14-/t23-,25-,26+,27+,30-,37-,38+,41-,45+/m1/s1

Sinónimos:

• (11beta,16beta)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
• 3-methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide
• A complex polyglucopyranose produced by the enzymatic hydrolysis of corn. It is primarily composed of alpha-1,4-glocopyranose linkage with less that 10 percent alpha-1,6 linkage
• platinum
• Adept (polysaccharide)
• 1-cyano-2-methyl-3-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)guanidine
• (3S)-2-{N-[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]-L-alanyl}-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
• A complex alpha-D-glycopyranan produced by the enzymatic hydrolysis of corn. It is primarily composed of (1-4)-alpha-D-glucopyrano linkage with less than 10 percent (1-6)-alpha linkage. Dextrin, having more than 85% of its molecules with molecular masses between 1640 and 45,000 with a claimed-average molecular mass of approximately 20,000
• 2-(2,4-difluorophenyl)-1,3-di(1H-1,2,4-triazol-1-yl)propan-2-ol
• 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
• [6-hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl]{4-[2-(piperidin-1-yl)ethoxy]phenyl}methanone
• 1-{2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
• (11beta)-11,17,21-trihydroxypregna-1,4-diene-3,20-dione
• N-(piperidin-2-ylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide
• azanide
• 2-(butan-2-yl)-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-2,4-dihydro-3H-1,2,4-triazol-3-one
• A complex polyglucopyranose produced by the enzymatic hydrolysis of corn. It is primarily composed of alpha-1,4-glocopyranose linkage with less that 10 percent alpha-1,6 linkage
• 1-{amino[(4-chlorophenyl)amino]methylidene}-2-propan-2-ylguanidine
• (11beta,16beta)-9-chloro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
• 3-(5H-dibenzo[a,d][7]annulen-5-yl)-N-methylpropan-1-amine
• 3-[({2-[(diaminomethylidene)amino]-1,3-thiazol-4-yl}methyl)sulfanyl]-N'-sulfamoylpropanimidamide
• 2-phenyl-1H-indene-1,3(2H)-dione
• 1-[4-(4-{[(2S,4R)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]ethanone
• Icodextrin
• 2-benzyl-4,5-dihydro-1H-imidazole
• 5-ethyl-5-phenylpyrimidine-2,4,6(1H,3H,5H)-trione
• 1-methyl-1,3-dihydro-2H-imidazole-2-thione
• methyl (3beta,16beta,17alpha,18beta,20alpha)-11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylate
• (6R,7R)-7-{[amino(phenyl)acetyl]amino}-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 1-(9H-carbazol-4-yloxy)-3-{[2-(2-methoxyphenoxy)ethyl]amino}propan-2-ol
• 5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}quinazoline-2,4-diamine
• Icodial
• 2-(diethylamino)ethyl 1,1'-bi(cyclohexyl)-1-carboxylate
• N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide
• 1-(1,2-benzoxazol-3-yl)methanesulfonamide
• 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one
• 6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
• (2S,5R,6R)-6-{[(2R)-2-amino-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• 1-methyl-3-phenylpyrrolidine-2,5-dione
• 5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)propyl]piperidin-4-yl}-1,3-dihydro-2H-benzimidazol-2-one
• Icodextrin, sodium chloride, sodium lactate, calcium chloride
• 1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]benzene
• N,N-dimethyl-2-[(2-methylphenyl)(phenyl)methoxy]ethanamine
• 2-hydroxy-3-(3-oxo-1-phenylbutyl)-4H-chromen-4-one
• N~4~-(7-chloroquinolin-4-yl)-N~1~,N~1~-diethylpentane-1,4-diamine
• 2-(hydroxymethyl)-4-(1-hydroxy-2-{[6-(4-phenylbutoxy)hexyl]amino}ethyl)phenol
• 1-cyclohexyl-1-phenyl-3-(pyrrolidin-1-yl)propan-1-ol
• ethyl 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylate
• (6R,7R)-3-[(carbamoyloxy)methyl]-7-{[(2E)-2-furan-2-yl-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 1,3-dibenzyl-2-oxodecahydrothieno[1',2':1,2]thieno[3,4-d]imidazol-5-ium
• 5-[bis(2-chloroethyl)amino]pyrimidine-2,4(1H,3H)-dione
• 5-[3-(tert-butylamino)-2-hydroxypropoxy]-3,4-dihydroquinolin-2(1H)-one
• N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine
• Adept
• 5-(3,4,5-trimethoxybenzyl)pyrimidine-2,4-diamine
• N,N-dimethyl-3-(10H-phenothiazin-10-yl)propan-1-amine
• Adept (polysaccharide)
• 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine
• 2-methyl-6-oxo-1,6-dihydro-3,4'-bipyridine-5-carbonitrile
• ethyl 1-methyl-4-phenylpiperidine-4-carboxylate
• 7',12'-dihydroxy-6,6'-dimethoxy-2,2',2'-trimethyltubocuraran-2'-ium
• (2S,3aS,6aS)-1-[(2S)-2-{[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino}propanoyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid (non-preferred name)
• 2-amino-1-(2,5-dimethoxyphenyl)propan-1-ol
• N-[4-(acridin-9-ylamino)-3-methoxyphenyl]methanesulfonamide
• cyclobutane-1,1-dicarboxylic acid
• (5Z,7E,22E)-9,10-secoergosta-5,7,22-trien-3-ol
• 5,5-diphenylimidazolidine-2,4-dione
• 4-amino-N-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide
• 2-[(5-nitro-1,3-thiazol-2-yl)carbamoyl]phenyl acetate
• N,N,2-trimethyl-3-(10H-phenothiazin-10-yl)propan-1-amine
• Adept
• N,2,3,3-tetramethylbicyclo[2.2.1]heptan-2-amine
• 5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine
• (11beta,17beta)-11-[4-(dimethylamino)phenyl]-17-hydroxy-17-(prop-1-yn-1-yl)estra-4,9-dien-3-one
• (5alpha,6alpha)-17-methyl-7,8-didehydro-4,5-epoxymorphinan-3,6-diol
• 2-[(carbamoyloxy)methyl]-2-methylpentyl propan-2-ylcarbamate (non-preferred name)
• 2-chloro-N-(2-chloroethyl)-N-methylethanamine
• 3-ethyl-4-methyl-N-[2-(4-{[(4-methylcyclohexyl)carbamoyl]sulfamoyl}phenyl)ethyl]-2-oxo-2,5-dihydro-1H-pyrrole-1-carboxamide
• (17beta)-estra-1,3,5(10)-triene-3,17-diol
• 5-fluoropyrimidine-2,4(1H,3H)-dione
• methyl propan-2-yl 4-(2,1,3-benzoxadiazol-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
• 17,21-dihydroxypregna-1,4-diene-3,11,20-trione
• 3,7-dimethyl-1-(5-oxohexyl)-3,7-dihydro-1H-purine-2,6-dione
• 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium
• 2-[({5-methoxy-1-[4-(trifluoromethyl)phenyl]pentylidene}amino)oxy]ethanamine
• 2-{(Z)-[5-(hydroxymethyl)-3H-indol-3-ylidene]methyl}-N'-pentylhydrazinecarboximidamide
• [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl](2,3-dihydro-1,4-benzodioxin-2-yl)methanone
• 5-methyl-N-[4-(trifluoromethyl)phenyl]-1,2-oxazole-4-carboxamide
• 2-{4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethanol
• 4-(dipropylsulfamoyl)benzoic acid
• 1-[(2S)-2-methyl-3-sulfanylpropanoyl]-L-proline
• Extraneal
• (1S,3S)-3,5,12-trihydroxy-3-(hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-arabino-hexopyranoside
• (8R)-3-(2-deoxypentofuranosyl)-3,4,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol
• (4Z)-4-(3,3-dimethyltriazanylidene)-4H-imidazole-5-carboxamide
• 9-(beta-D-arabinofuranosyl)-9H-purin-6-amine hydrate (1:1)
• (1R,5R)-3-[(3-hydroxy-2-phenylpropanoyl)oxy]-8-methyl-8-(propan-2-yl)-8-azoniabicyclo[3.2.1]octane
• platinum(2+) ethanedioate - cyclohexane-1,2-diamine (1:1:1)
• 6-(5-chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate
• 4-amino-N-[2-(diethylamino)ethyl]benzamide
• N,3-bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide
• 4-(2-{[4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)benzene-1,2-diol
• (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate
• 2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
• (1S,3S)-3-acetyl-3,5,12-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside
• 4-{[(E)-(4-chlorophenyl)(3-fluoro-6-oxocyclohexa-2,4-dien-1-ylidene)methyl]amino}butanamide
• 3-ethyl-3-methylpyrrolidine-2,5-dione
• 4-(diethylamino)but-2-yn-1-yl cyclohexyl(hydroxy)phenylacetate
• (3S)-9,10-secocholesta-5,7,10-trien-3-ol
• 9-methyl-3-(2H-tetrazol-5-yl)-4H-pyrido[1,2-a]pyrimidin-4-one
• 2-[(1E)-1-(4-methylphenyl)-3-pyrrolidin-1-ylprop-1-en-1-yl]pyridine
• 4-chloro-N-(propylcarbamoyl)benzenesulfonamide
• (2S,5R,6R)-6-{[(2R)-2-{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• 2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-5-ethyl-4-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
• (5alpha)-3,14-dihydroxy-17-methyl-4,5-epoxymorphinan-6-one
• N-[(1R)-1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl-L-proline
• ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylate
• N~2~-[(1S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-proline
• 5-{4-[(6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-chromen-2-yl)methoxy]benzyl}-1,3-thiazolidine-2,4-dione
• 6-phenylpteridine-2,4,7-triamine
• 3-(dibutylamino)-1-[1,3-dichloro-6-(trifluoromethyl)phenanthren-9-yl]propan-1-ol
• 1-{[(1Z)-(5-nitrofuran-2-yl)methylidene]amino}imidazolidine-2,4-dione
• ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
• 4-aminohex-5-enoic acid
• 2,2'-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl]-3-C-formyl-alpha-L-lyxofuranosyl}oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine
• (6R,7R)-7-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-8-oxo-3-[(1E)-prop-1-en-1-yl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 1-(beta-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide
• 2-[(5-nitrofuran-2-yl)methylidene]hydrazinecarboxamide
• 2-O-sulfohexopyranuronosyl-(1->4)-2-deoxy-3-O-sulfo-2-(sulfoamino)hexopyranosyl-(1->4)-2-O-sulfohexopyranuronosyl-(1->4)-2-(acetylamino)-2-deoxy-6-O-sulfohexopyranose
• 3-[(1R,2S)-2-amino-1-hydroxypropyl]phenol
• methyl (5S,7S,9S)-9-[(2beta,3beta,4beta,5alpha,12beta,19alpha)-3-carbamoyl-3,4-dihydroxy-16-methoxy-1-methyl-6,7-didehydroaspidospermidin-15-yl]-5-ethyl-5-hydroxy-1,4,5,6,7,8,9,10-octahydro-2H-3,7-methanoazacycloundecino[5,4-b]indole-9-carboxylate
• [2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetic acid
• (3S)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine
• 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
• 2,2'-hexane-1,6-diylbis(1-{amino[(4-chlorophenyl)amino]methylidene}guanidine)
• [(3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis[1,3]dioxolo[4,5-b:4',5'-d]pyran-3a-yl]methyl sulfamate (non-preferred name)
• (3E)-6-oxo-3-{[4-(pyridin-2-ylsulfamoyl)phenyl]hydrazono}cyclohexa-1,4-diene-1-carboxylic acid
• 5,5-dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]imidazolidine-2,4-dione
• propan-2-yl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate
• N,N-bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide
• 2,2'-[(1,4-dioxobutane-1,4-diyl)bis(oxy)]bis(N,N,N-trimethylethanaminium)
• 3-cyclohexyl-N,N,N-triethyl-3-hydroxy-3-phenylpropan-1-aminium
• 2-{4-[(1Z)-4-chloro-1,2-diphenylbut-1-en-1-yl]phenoxy}-N,N-dimethylethanamine
• [(3S)-3-{[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino}-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic acid
• (9S,12Z,14R,15R,16S,17S,18S,19S,20R,21R,22Z,24Z)-6,18,20-trihydroxy-14-methoxy-7,9,15,17,19,21,25-heptamethyl-1'-(2-methylpropyl)-5,10,26-trioxo-3,5,9,10-tetrahydrospiro[9,4-(epoxypentadeca[1,11,13]trienoimino)furo[2',3':7,8]naphtho[1,2-d]imidazole-2,4'-piperidin]-16-yl acetate
• 1-{4-[2-(cyclopropylmethoxy)ethyl]phenoxy}-3-(propan-2-ylamino)propan-2-ol
• 8-chloro-11-(4-methylpiperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine
• (1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetic acid
• (3Z)-3-[hydroxy(pyridin-2-ylamino)methylidene]-2-methyl-2,3-dihydro-4H-thieno[2,3-e][1,2]thiazin-4-one 1,1-dioxide
• 2'-deoxy-5-iodouridine
• (5alpha)-3,14-dihydroxy-17-prop-2-en-1-yl-4,5-epoxymorphinan-6-one
• 4-amino-1-[(2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2(1H)-one
• 4-[(3-methylphenyl)amino]-N-(propan-2-ylcarbamoyl)pyridine-3-sulfonamide
• (1S)-1-{[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]methyl}dodecyl N-formyl-L-leucinate
• 2-amino-9-[(2-hydroxyethoxy)methyl]-3,9-dihydro-6H-purin-6-one
• 4-amino-5-chloro-N-{1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-yl}-2-methoxybenzamide
• N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine
• N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino]propyl}tetrahydrofuran-2-carboxamide
• 5-chloro-1,3-benzoxazol-2(3H)-one
• 5-ethyl-3-methyl-5-phenylimidazolidine-2,4-dione
• (11E)-13-[(2S,3R,4R,5S)-3,4-dihydroxy-5-({(2R,3S)-3-[(1S,2S)-2-hydroxy-1-methylpropyl]oxiran-2-yl}methyl)tetrahydro-2H-pyran-2-yl]-12-methyl-10-oxotridec-11-enoic acid (non-preferred name)

Icodextrin

CAS: 337376-15-5

Pureza: 95%

Forma y color: Solid

Peso molecular: G/Mol

Ref: IN-DA0037O4