CAS 34031-32-8
:Auranofin
Descripción:
Auranofin es un compuesto que contiene oro, utilizado principalmente en el tratamiento de la artritis reumatoide. Pertenece a la clase de medicamentos conocidos como sales de oro, que tienen propiedades antiinflamatorias. La fórmula química de Auranofin es C20H17AuO9PS, lo que indica que contiene oro, azufre, fósforo y varios componentes orgánicos. Auranofin funciona modulando la respuesta inmune e inhibiendo la actividad de ciertas enzimas involucradas en la inflamación. Se administra típicamente por vía oral y es conocido por su toxicidad relativamente baja en comparación con otros compuestos de oro. Sin embargo, aún puede causar efectos secundarios, incluyendo trastornos gastrointestinales y posibles reacciones alérgicas. El mecanismo de acción del compuesto implica la inhibición de la activación de macrófagos y la modulación de la producción de citoquinas, contribuyendo a sus efectos terapéuticos. Auranofin también ha despertado interés en la investigación por sus posibles aplicaciones más allá de la artritis, incluyendo sus propiedades antiparasitarias y anticancerígenas. Al igual que con cualquier medicamento, su uso debe ser monitoreado por profesionales de la salud para gestionar eficazmente cualquier efecto adverso.
Fórmula:C20H34AuO9PS
InChI:InChI=1/C6H15P.Au/c1-4-7(5-2)6-3;/h4-6H2,1-3H3;/q;+1
Clave InChI:InChIKey=AUJRCFUBUPVWSZ-XTZHGVARSA-M
SMILES:O(C(C)=O)[C@@H]1[C@@H](OC(C)=O)[C@H]([S-][Au+][P](CC)(CC)CC)O[C@H](COC(C)=O)[C@H]1OC(C)=O
Sinónimos:- (1-Thio-beta-D-glucopyranosato)(triethylphosphine)gold 2,3,4,6-tetraacetate
- 3,4,5-Triacetoxy-6-(Acetoxymethyl)Tetrahydropyran-2-Thiolate
- Aktil
- Auranofina
- Auranofine
- Crisinor
- Crisofin
- Gold Salt
- Gold(+1) Cation
- Gold, (1-thio-β-<span class="text-smallcaps">D</span>-glucopyranosato)(triethylphosphine)-, 2,3,4,6-tetraacetate
- Gold, (1-thio-β-<span class="text-smallcaps">D</span>-glucopyranose 2,3,4,6-tetraacetato-S)(triethylphosphine)-
- Gold, (1-thio-β-D-glucopyranosato)(triethylphosphine)-, 2,3,4,6-tetraacetate
- Gold, (1-thio-β-D-glucopyranose 2,3,4,6-tetraacetato-S)(triethylphosphine)-
- Gold, [1-(thio-κS)-β-<span class="text-smallcaps">D</span>-glucopyranose 2,3,4,6-tetraacetato](triethylphosphine)-
- Gold, [1-(thio-κS)-β-D-glucopyranose 2,3,4,6-tetraacetato](triethylphosphine)-
- Nsc 321521
- Phosphine, Triethyl-, Gold(1+) Salt (1:1)
- Ridaura
- Ridauran
- Skf 39162
- Skf 39162D
- Triethylphosphonium
- [(Tetra-O-acetyl-β-<span class="text-smallcaps">D</span>-glucopyranosyl)thio](triethylphosphine)gold
- [(Tetra-O-acetyl-β-D-glucopyranosyl)thio](triethylphosphine)gold
- [1-(Thio-κS)-β-<span class="text-smallcaps">D</span>-glucopyranose 2,3,4,6-tetraacetato](triethylphosphine)gold
- β-<span class="text-smallcaps">D</span>-Glucopyranose, 1-thio-, 2,3,4,6-tetraacetate, gold complex
- β-D-Glucopyranose, 1-thio-, 2,3,4,6-tetraacetate, gold complex
- [1-(Thio-κS)-β-D-glucopyranose 2,3,4,6-tetraacetato](triethylphosphine)gold
- 3,4,5-Triacetyloxy-6-(acetyloxymethyl) oxane-2-thiolate triethylphosphanium
- gold,(1-thio-beta-d-glucopyranose2,3,4,6-tetraacetato-s)(triethylphosphine)
- Gold, [1-(thio-kS)-b-D-glucopyranose2,3,4,6-tetraacetato](triethylphosphine)-
- sk&f39162
- 2,3,4,6-tetra-o-acetyl-1-thio-beta-d-glucopyranosato-s(triethylphosphine)gol
- sk&f39162d
- (1-thio-beta-d-glucopyranosato)-(triethylphosphine)gold2,3,4,6-tetraacetate
- (1-Thio-β-D-glucopyranosato)(triethylphosphine)gold-2，3，4，6-tetraacetate
- gold,(1-thio-beta-d-glucopyranosato-s)(triethylphosphine)-,2,3,4,6-tetraaceta
- AURANOFIN
- sk&fd-39162
- Adtil
- Auranofin, >=98%
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Encontrado 9 productos.
(1-Thio-β-D-glucopyranosato)(triethylphosphine)gold 2,3,4,6-tetraacetate
CAS:Fórmula:C20H34AuO9PSPureza:98%Forma y color:SolidPeso molecular:678.4839Ref: IN-DA00382F
1gA consultar1mg52,00€10mg89,00€50mg168,00€100mg271,00€250mgA consultar500mgA consultarAuranofin
CAS:<p>Auranofin (SKF-39162), an antirheumatic, treats rheumatoid arthritis and eases joint pain and stiffness.</p>Fórmula:C20H34AuO9PSPureza:97% - 99.01%Forma y color:White Crystalline Powder SolidPeso molecular:678.49((2S,3R,4S,5R,6R)-3,4,5-Triacetoxy-6-(Acetoxymethyl)Tetrahydro-2H-Pyran-2-Thio)(Triethylphosphine)Gold
CAS:((2S,3R,4S,5R,6R)-3,4,5-Triacetoxy-6-(Acetoxymethyl)Tetrahydro-2H-Pyran-2-Thio)(Triethylphosphine)GoldPureza:98%Peso molecular:678.5g/molAuranofine
CAS:Fórmula:C20H34AuO9PSPureza:≥ 95.0%Forma y color:White to off-white solidPeso molecular:678.48Auranofin
CAS:<p>Auranofin is a chrysotherapeutic agent which inhibits histamine release from human basophils. Auranofin is gold-containing salt extensively used in the treatment of rheumatoid arthritis. Auranofin has antimicrobial properties and inhibits the growth of Clostridium difficile more effectively than vancomycin and metronidazole. According to in vitro studies carried out in 2020, auranofin inhibits the replication of coronavirus SARS-CoV-2 and reduces inflammation in human cells.</p>Fórmula:C20H34AuO9PSForma y color:White Off-White PowderPeso molecular:678.49 g/molAuranofin
CAS:Producto controlado<p>Applications Auranofin is a new oral gold-based antiarthritis drug. Auranofin inhibits various leukocyte activation pathways at multiple sites. Auranofin inhibits the release of inflammatory mediators from human macrophages, basophils, and pulmonary mast cells. Auranofin is an efficient inducer of mitochondrial membrane permeability transition pore in the presence of calcium ions related to its inhibition of mitochondrial thioredoxin reductase.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kizu, R., et al.: Chem. Pharm. Bull., 41, 1261 (1993), Itokazu, M., et al.: Clin. Ther., 17, 60 (1995), Kean, W.F., et al.: Br. J. Rheumatol., 36, 560 (1997),<br></p>Fórmula:C20H34AuO9PSForma y color:NeatPeso molecular:678.48
