CAS 342-69-8

6-Metilmercaptopurina ribósido

Descripción:

6-Metilmercaptopurina ribósido es un derivado de nucleósido de purina caracterizado por la presencia de un azúcar ribosa unido a una base de 6-metiltiopurina. Este compuesto es notable por su papel en el metabolismo de ácidos nucleicos y tiene implicaciones en farmacología, particularmente en el contexto del metabolismo de purinas y aplicaciones terapéuticas potenciales. Exhibe propiedades típicas de los nucleósidos, incluida la capacidad de participar en reacciones bioquímicas que involucran nucleótidos y ácidos nucleicos. La presencia del grupo metiltio en la posición 6 del anillo de purina influye en su actividad biológica y solubilidad. 6-Metilmercaptopurina ribósido puede ser sintetizado a través de diversas vías químicas y a menudo se estudia por sus efectos en el crecimiento y proliferación celular, particularmente en la investigación del cáncer. Su número CAS, 342-69-8, es un identificador único que facilita la catalogación e identificación de este compuesto en la literatura científica y bases de datos. En general, esta sustancia es de interés tanto en la investigación bioquímica como en aplicaciones terapéuticas potenciales debido a sus características estructurales y funcionales.

Fórmula: C₁₁H₁₄N₄O₄S

InChI: InChI=1S/C11H14N4O4S/c1-20-10-6-9(12-3-13-10)15(4-14-6)11-8(18)7(17)5(2-16)19-11/h3-5,7-8,11,16-18H,2H2,1H3/t5-,7-,8-,11-/m1/s1

Clave InChI: InChIKey=ZDRFDHHANOYUTE-IOSLPCCCSA-N

SMILES: O[C@H]1[C@H](N2C=3C(N=C2)=C(SC)N=CN3)O[C@H](CO)[C@H]1O

Sinónimos:

• 6-(Methylmercapto)-9-(β-<span class="text-smallcaps">D</span>-ribofuranosyl)purine
• 6-(Methylmercapto)purine ribonucleoside
• 6-(Methylthio)-9-β-<span class="text-smallcaps">D</span>-ribofuranosyl-9H-purine
• 6-(Methylthio)-9-β-<span class="text-smallcaps">D</span>-ribofuranosylpurine
• 6-(Methylthio)purine ribonucleoside
• 6-Methylmercapto-9-(β-D-ribofuranosyl)purine
• 6-Methylthioinosine
• 6-Methylthiopurine riboside
• 6-Mmpr
• 6-S-Methyl-6-thioinosine
• 9H-Purine, 6-(methylthio)-9-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
• Inosine, 6-S-methyl-6-thio-
• Methylthioinosine
• NSC 40774
• NSC 49555
• Sq 21977
• β-<span class="text-smallcaps">D</span>-Ribosyl-6-methylthiopurine
• 6-Methylmercaptopurine riboside

(2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-(methylthio)-9H-purin-9-yl)tetrahydrofuran-3,4-diol

CAS: 342-69-8

(2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-(methylthio)-9H-purin-9-yl)tetrahydrofuran-3,4-diol

Pureza: 98%

Peso molecular: 298.32g/mol

Ref: 54-OR1059382

6-Methylmercapto-9-(b-D-ribofuranosyl)purine

CAS: 342-69-8

Fórmula: C₁₁H₁₄N₄O₄S

Peso molecular: 298.32

Ref: 7W-GN6238

6-Methylmercaptopurine riboside

CAS: 342-69-8

6-Methylmercaptopurine riboside is a purine nucleoside analogue applicable to biochemical experiments and drug synthesis studies.

Fórmula: C₁₁H₁₄N₄O₄S

Forma y color: Solid

Peso molecular: 298.32

Ref: TM-TNU0494

6-Methylmercaptopurine Riboside

Producto controlado

CAS: 342-69-8

Applications 6-Methylmercaptopurine Riboside (cas# 342-69-8) is a compound useful in organic synthesis.

Fórmula: C₁₁H₁₄N₄O₄S

Forma y color: White To Off-White

Peso molecular: 298.32

Ref: TR-M321035

6-Methylmercapto-9-(b-D-ribofuranosyl)purine

CAS: 342-69-8

6-Methylmercapto-9-(b-D-ribofuranosyl)purine (6MMPR) is a nucleotide analog that is synthesized through the process of ribosylation. It has been shown to be reactive and inflammatory in the colon, which may be due to its role as an enzyme inhibitor. 6MMPR inhibits target enzymes such as 2-methylthio-6-chloropurine riboside, which are involved in DNA synthesis and repair. This drug also has anti-inflammatory properties, which may be due to its ability to inhibit the production of inflammatory cytokines by activated immune cells. 6MMPR is used for the treatment of bowel diseases such as Crohn's disease and ulcerative colitis.

Fórmula: C₁₁H₁₄N₄O₄S

Pureza: Min. 95%

Forma y color: White Powder

Peso molecular: 298.32 g/mol

Ref: 3D-NM06304

6-Methylmercaptopurine Riboside-d3 (Major)

Producto controlado

CAS: 342-69-8

Applications 6-Methylmercaptopurine Riboside-d3 is the isotope labelled analog of 6-Methylmercaptopurine Riboside (M321035); a thiopurine prodrug used as potential treatment for patients with inflammatory bowel disease.
References Haglund, S., et al.: Therap. Drug. Monitor., 33, 200 (2011); Arendt, C.S., et al.: J. BIol. Chem., 285, 6024 (2010); Fotoohi, A.K., et al.: Biochem. Pharmacol., 72, 816 (2006)

Fórmula: C₁₁H₁₁D₃N₄O₄S

Forma y color: White To Off-White

Peso molecular: 301.34

Ref: TR-M321038