CAS 34604-60-9

Ácido 5-hidroxipirazina-2-carboxílico

Descripción:

Ácido 5-hidroxipirazina-2-carboxílico, con el número CAS 34604-60-9, es un compuesto orgánico caracterizado por su estructura de anillo de pirazina, que es un anillo aromático de seis miembros que contiene dos átomos de nitrógeno. Este compuesto presenta un grupo hidroxilo (-OH) y un grupo ácido carboxílico (-COOH) unidos al anillo de pirazina, lo que contribuye a su naturaleza polar y potencial para la formación de enlaces de hidrógeno. Típicamente es un sólido cristalino blanco a blanco sucio, soluble en agua y varios disolventes orgánicos, lo que mejora su utilidad en reacciones químicas y formulaciones. La presencia de ambos grupos funcionales permite una reactividad diversa, lo que lo convierte en un intermediario valioso en la síntesis orgánica, particularmente en el desarrollo de productos farmacéuticos y agroquímicos. Además, su actividad biológica puede incluir propiedades antioxidantes, aunque las aplicaciones específicas pueden variar. Al igual que con muchos compuestos orgánicos, el manejo debe hacerse con cuidado, siguiendo los protocolos de seguridad apropiados para mitigar cualquier peligro potencial asociado con su uso.

Fórmula: C₅H₄N₂O₃

InChI: InChI=1S/C5H4N2O3/c8-4-2-6-3(1-7-4)5(9)10/h1-2H,(H,7,8)(H,9,10)

Clave InChI: InChIKey=CGQFCIHUUCMACC-UHFFFAOYSA-N

SMILES: C(O)(=O)C1=CNC(=O)C=N1

Sinónimos:

• 2-Pyrazinecarboxylic acid, 4,5-dihydro-5-oxo-
• 4,5-Dihydro-5-oxo-2-pyrazinecarboxylic acid
• 5-Hydropyrazine-2-Carboxylic Acid
• 5-Hydroxy-2-Pyrazinecarboxylic Acid
• 5-Hydroxy-Pyrazine-2-Carboxylic Acid
• 5-Hydroxypyrazine-2-Carboxylic Acid
• 5-Hydroxypyrazinoic Acid
• 5-Oxo-4,5-dihydropyrazine-2-carboxylic acid
• Pyrazinecarboxylic Acid, 4,5-Dihydro-5-Oxo-
• Pyrazinecarboxylic acid, 5-hydroxy-

5-Hydroxypyrazine-2-Carboxylic Acid

CAS: 34604-60-9

Fórmula: C₅H₄N₂O₃

Pureza: 98%

Forma y color: Solid

Peso molecular: 140.0969

Ref: IN-DA00BZJ0

5-Hydroxypyrazine-2-Carboxylic Acid

CAS: 34604-60-9

5-Hydroxypyrazine-2-Carboxylic Acid is a metabolite of anti-tuberculosis drug pyrazinamide.

Fórmula: C₅H₄N₂O₃

Forma y color: Brownish Powder

Peso molecular: 140.1

Ref: TM-T10171

5-Hydroxy-2-Pyrazinecarboxylic Acid

CAS: 34604-60-9

Fórmula: C₅H₄N₂O₃

Peso molecular: 140.10

Ref: 4Z-P-240003

5-Hydroxypyrazine-2-carboxylic acid

CAS: 34604-60-9

5-Hydroxypyrazine-2-carboxylic acid

Fórmula: C₅H₄N₂O₃

Pureza: 97%

Forma y color: dark brown solid

Peso molecular: 140.10g/mol

Ref: 54-OR40051

5-Hydroxypyrazine-2-carboxylic Acid

CAS: 34604-60-9

Applications A versatile building block for the synthesis of new antituberculous agents. A metabolite of Pyrazinamide (P840600).
References Wieser, M. et al.: Appl. Microbiol. Biotech., 48, 174 (1997); Lacroix, C. et al.: Eur. J. Clin. Pharmacol., 36, 395 (1989);

Fórmula: C₅H₄N₂O₃

Forma y color: Light Yellow

Peso molecular: 140.10

Ref: TR-H952675

5-Hydroxypyrazine-2-carboxylic acid

CAS: 34604-60-9

Fórmula: C₅H₄N₂O₃

Pureza: 97%

Forma y color: Solid

Peso molecular: 140.098

Ref: 10-F037360

5-Hydroxypyrazine-2-carboxylic acid

CAS: 34604-60-9

5-Hydroxypyrazine-2-carboxylic acid is a drug that inhibits the activation of proteins involved in cell signaling pathways. It has been shown to have an inhibitory effect on the activation of protein kinase C, which plays a key role in the proliferation and differentiation of cells. 5-Hydroxypyrazine-2-carboxylic acid also inhibits sorafenib, a drug used for the treatment of cancer. Sorafenib is metabolized in rats by cytochrome P450 (CYP) enzymes, which are found in human liver tissue as well. The metabolism rate of sorafenib can be reduced by coadministration with caffeine or other substances that induce CYP activity. 5-Hydroxypyrazine-2-carboxylic acid is not active against pyrazinoic acid and pyrazine-2 carboxylate, which are metabolites produced by CYP enzymes.

Fórmula: C₅H₄N₂O₃

Pureza: Min. 98 Area-%

Forma y color: Brown Powder

Peso molecular: 140.1 g/mol

Ref: 3D-FH24492

5-Hydroxy-2-Pyrazinecarboxylic Acid-13C3

CAS: 34604-60-9

Fórmula: C₅H₄N₂O₃

Peso molecular: 143.07

Ref: 4Z-P-240004