CAS 3556-56-7

Éster 4-nitrofenil de N-[(fenilmetoxi)carbonil]-L-tirosina

Descripción:

Éster 4-nitrofenil de N-[(fenilmetoxi)carbonil]-L-tirosina, con número CAS 3556-56-7, es un compuesto químico que pertenece a la clase de derivados de aminoácidos. Presenta una estructura de backbone de tirosina, que es un aminoácido aromático conocido por su papel en la síntesis de proteínas y como precursor de neurotransmisores. El compuesto se caracteriza por la presencia de un grupo protector fenilmetoxicarbonilo (Pmc), que se utiliza comúnmente en la síntesis de péptidos para proteger el grupo amino del aminoácido. Además, el grupo éster de 4-nitrofenilo contribuye a su reactividad, haciéndolo útil en diversas reacciones químicas, particularmente en la síntesis de péptidos y otras moléculas orgánicas complejas. El compuesto es típicamente un sólido a temperatura ambiente y puede exhibir solubilidad en disolventes orgánicos. Sus propiedades, como el punto de fusión, solubilidad y reactividad, pueden variar según las condiciones específicas y la pureza de la muestra. En general, este compuesto es significativo en la síntesis orgánica y la bioquímica, particularmente en el desarrollo de productos farmacéuticos y bioconjugados.

Fórmula: C₂₃H₂₀N₂O₇

InChI: InChI=1S/C23H20N2O7/c26-19-10-6-16(7-11-19)14-21(24-23(28)31-15-17-4-2-1-3-5-17)22(27)32-20-12-8-18(9-13-20)25(29)30/h1-13,21,26H,14-15H2,(H,24,28)/t21-/m0/s1

Clave InChI: InChIKey=WUHIFOXZYIQZFP-NRFANRHFSA-N

SMILES: [C@H](CC1=CC=C(O)C=C1)(C(OC2=CC=C(N(=O)=O)C=C2)=O)NC(OCC3=CC=CC=C3)=O

Sinónimos:

• 4-nitrophenyl N-[(benzyloxy)carbonyl]tyrosinate
• <span class="text-smallcaps">L</span>-Tyrosine, N-[(phenylmethoxy)carbonyl]-, 4-nitrophenyl ester
• N-(Benzyloxycarbonyl)-<span class="text-smallcaps">L</span>-tyrosine p-nitrophenyl ester
• N-CBZ-L-Tyrosine-p-nitrophenyl ester N-Carbobenzyloxy-L-tyrosine-p-nitrophenyl ester
• N-Carbobenzoxy-<span class="text-smallcaps">L</span>-tyrosine p-nitrophenyl ester
• N-[(Phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-tyrosine 4-nitrophenyl ester
• N-α-Carbobenzoxy-<span class="text-smallcaps">L</span>-tyrosine p-nitrophenyl ester
• NSC 88489
• Tyrosine, N-carboxy-, N-benzyl p-nitrophenyl ester, <span class="text-smallcaps">L</span>-
• Z-Tyr-ONp
• p-Nitrophenyl N-benzyloxycarbonyl-<span class="text-smallcaps">L</span>-tyrosine
• α-N-Benzyloxycarbonyl-<span class="text-smallcaps">L</span>-tyrosine p-nitrophenyl ester
• Tyrosine, N-carboxy-, N-benzyl p-nitrophenyl ester, L-
• N-α-Carbobenzoxy-L-tyrosine p-nitrophenyl ester
• N-[(Phenylmethoxy)carbonyl]-L-tyrosine 4-nitrophenyl ester
• N-(Benzyloxycarbonyl)-L-tyrosine p-nitrophenyl ester

Z-Tyr-Onp

CAS: 3556-56-7

Fórmula: C₂₃H₂₀N₂O₇

Pureza: 98%

Forma y color: Solid

Peso molecular: 436.4141

Ref: IN-DA00BYAK

Z-Tyr-Onp

CAS: 3556-56-7

Z-Tyr-Onp

Pureza: 98%

Peso molecular: 436.41g/mol

Ref: 54-OR1015469

Z-L-tyrosine 4-nitrophenyl ester

CAS: 3556-56-7

Z-L-tyrosine 4-nitrophenyl ester is a synthetic, inactivated amide that binds to the active site of enzyme, preventing its enzymatic activity. It prevents the formation of clots by cleaving the clotting factors and is used in blood transfusions. Z-L-tyrosine 4-nitrophenyl ester has been shown to inhibit the synthesis of surfactant and is used as an antiseptic. This drug can be prepared by reacting L-tyrosine with nitrophenol (NO2) in the presence of a base such as sodium hydroxide or potassium carbonate, followed by purification on sephadex g-100 columns. The product is then treated with hydrostatic pressure to remove any unreacted starting materials. This drug also has a sedimentation rate of about 1.5 x 10^6 cm/s.

Fórmula: C₂₃H₂₀N₂O₇

Pureza: Min. 95%

Forma y color: White/Off-White Solid

Peso molecular: 436.41 g/mol

Ref: 3D-FT47319

Z-Tyr-ONp

CAS: 3556-56-7

Z-Tyr-ONp is a synthetic, water soluble, non-toxic fibrinogen activator. It has been shown to be effective at low concentrations in the activation of fibrinogen and in the prevention of clotting. Z-Tyr-ONp hydrolyzes fibrinogen to form fibrin clots, which are needed for blood coagulation. This process is mediated by the enzyme alpha-thrombin and is dependent on calcium ions. Z-Tyr-ONp also exhibits surfactant properties that allow it to stabilize micelles that contain lipase enzymes and bile salts, which are required for digestion of dietary fats. The presence of lipase enzymes can enhance the proteolytic activity of Z-Tyr-ONp and increase its ability to dissolve clots.

Fórmula: C₂₃H₂₀N₂O₇

Pureza: Min. 95%

Peso molecular: 436.41 g/mol

Ref: 3D-SYN-3016