CAS 355806-00-7

1,1-Dimetiletil (3R,5S,6E)-7-[4-(4-fluorofenil)-6-(1-metiletil)-2-[metil(metilsulfonil)amino]-5-pirimidinil]-3,5-dihidroxi-6-heptenoato

Descripción:

1,1-Dimetiletil (3R,5S,6E)-7-[4-(4-fluorofenil)-6-(1-metiletil)-2-[metil(metilsulfonil)amino]-5-pirimidinil]-3,5-dihidroxi-6-heptenoato, con número CAS 355806-00-7, es un compuesto orgánico complejo caracterizado por su intrincada estructura molecular, que incluye múltiples grupos funcionales como hidroxilo, moieties de pirimidina y sulfonamida. Este compuesto es notable por su estereoquímica, presentando centros quirales específicos que contribuyen a su actividad biológica. La presencia de un grupo fluorofenilo sugiere interacciones potenciales con objetivos biológicos, lo que lo hace de interés en la química medicinal. Su esqueleto de heptenoato indica que puede exhibir insaturación, lo que puede influir en su reactividad y estabilidad. La solubilidad del compuesto, el punto de fusión y otras propiedades físicas dependerían de sus interacciones moleculares y la presencia de sustituyentes. En general, esta sustancia probablemente será estudiada por sus propiedades farmacológicas, particularmente en el contexto del desarrollo de fármacos y aplicaciones terapéuticas.

Fórmula: C₂₆H₃₆FN₃O₆S

InChI: InChI=1S/C26H36FN3O6S/c1-16(2)23-21(13-12-19(31)14-20(32)15-22(33)36-26(3,4)5)24(17-8-10-18(27)11-9-17)29-25(28-23)30(6)37(7,34)35/h8-13,16,19-20,31-32H,14-15H2,1-7H3/b13-12+/t19-,20-/m1/s1

Clave InChI: InChIKey=IJHZGLLGELSZAF-OKLSWEBGSA-N

SMILES: C(=C/[C@H](C[C@H](CC(OC(C)(C)C)=O)O)O)\C=1C(=NC(N(S(C)(=O)=O)C)=NC1C(C)C)C2=CC=C(F)C=C2

Sinónimos:

• (+)-(3r, 5s)-7-[4-(4-Fluorophenyl)-6-Isopropyl-2-(N-Methyl-N-Methanesulfonylamino)Pyrimidin-5-Yl]-(3, 5)-Dihydroxy-6(E)-Heptenoate
• (3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[(methanesulfonyl)methylamino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid tert-butyl ester
• (3R,5S,6E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonyl amino)pyrinidine-5-yl]-3,5-dihydrosy-6-heptane acid,dimethylethyl ester
• 1,1-Dimethylethyl (3R,5S,6E)-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoate
• 6-Heptenoic acid, 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-, 1,1-dimethylethyl ester, (3R,5S,6E)-
• Rosuvastatin calcium intermediate R-3
• Rosuvastatin tert-Butyl Ester
• tert-Butyl rosuvastatin
• tert-Butyl(6E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-(3R,5S)-3,5-dihydroxyhept-6-enoate
• tert-butyl (3R,5S,6E)-7-{4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoate

6-Heptenoic acid,7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-, 1,1-dimethylethyl ester, (3R,5S,6E)-

CAS: 355806-00-7

Fórmula: C₂₆H₃₆FN₃O₆S

Pureza: 98%

Forma y color: Solid

Peso molecular: 537.6439

Ref: IN-DA00I726

Rosuvastatin tert-butyl ester

CAS: 355806-00-7

Rosuvastatin tert-butyl ester

Pureza: 98%

Peso molecular: 537.64g/mol

Ref: 54-PC111420

Rosuvastatin tert-Butyl Ester

CAS: 355806-00-7

Fórmula: C₂₆H₃₆FN₃O₆S

Forma y color: White To Off-White Solid

Peso molecular: 537.65

Ref: 4Z-R-099

Rosuvastatin Impurity 37

CAS: 355806-00-7

Fórmula: C₂₆H₃₇N₃O₆S

Forma y color: White To Off-White Solid

Peso molecular: 519.66

Ref: 4Z-R-0995

Rosuvastatin tert-Butyl Ester

Producto controlado

CAS: 355806-00-7

Stability Hygroscopic
Applications Rosuvastatin tert-Butyl Ester, is a metabolite of Rosuvastatin (R700500) a selective, competitive HMG-CoA reductase inhibitor.
References Watanabe, M., et al.: Bioorg. Med. Chem., 5, 437 (1997), Lee, E., et al.: Clin. Pharmacol. Ther., 78, 330 (2005), Ferdinand, K.C., et al.: Am. J. Cardiol., 97, 229 (2006),

Fórmula: C₂₆H₃₆FN₃O₆S

Forma y color: Neat

Peso molecular: 537.64

Ref: TR-R700540

(3R,5S,6E)-7-[4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-[(METHANESULFONYL) METHYLAMINO]PYRIMIDIN-5-YL]-3,5-DIHYDROXYHEPT-6-ENOIC ACID TERT-BUTYL ESTER

CAS: 355806-00-7

Pureza: 98%

Peso molecular: 537.6500244

Ref: 10-F835716

Rosuvastatin Acid t-Butyl Ester

CAS: 355806-00-7

Fórmula: C₂₆H₃₆FN₃O₆S

Peso molecular: 537.65

Ref: ST-EA-CP-R1080

Tert-Butyl Rosuvastatin

CAS: 355806-00-7

Tert-Butyl Rosuvastatin is a synthetic statin. It has a high melting point, which can be used to separate the optical isomers. The tert-butyl group of the rosuvastatin molecule makes it soluble in organic solvents such as tetrahydrofuran, while the ester side chain makes it hydrolysis resistant. Tert-Butyl Rosuvastatin was found to be free of impurities and had a purity of at least 99% by liquid chromatography analysis. Analysis by mass spectrometry confirmed that no other alkali metal ions were present at greater than 0.1%.

Fórmula: C₂₆H₃₆FN₃O₆S

Pureza: Min. 95%

Peso molecular: 537.65 g/mol

Ref: 3D-FT35382