CAS 35920-39-9

1-(6-Amino-9H-purin-9-il)-1-desoxi-N-etil-β-D-ribofuranuronamida

Descripción:

1-(6-Amino-9H-purin-9-il)-1-desoxi-N-etil-β-D-ribofuranuronamida, con el número CAS 35920-39-9, es un derivado de purina que exhibe características típicas de los nucleósidos. Este compuesto presenta una base de purina, específicamente adenina, unida a un moiety de azúcar ribofuranosa, que está modificada por la presencia de un grupo etilo en la posición del nitrógeno. El grupo amino en la posición 6 del anillo de purina contribuye a su potencial actividad biológica, posiblemente influyendo en las interacciones con estructuras de ácidos nucleicos o enzimas. La presencia del grupo desoxi indica que carece de un átomo de oxígeno en la posición 2' de la ribosa, lo cual es significativo para su estabilidad y reactividad. Este compuesto puede ser de interés en la investigación bioquímica, particularmente en estudios relacionados con el metabolismo de ácidos nucleicos, actividad antiviral, o como un posible agente terapéutico. Su solubilidad, estabilidad y reactividad dependerían de las condiciones específicas del entorno, como el pH y la temperatura, así como de la presencia de otras especies químicas.

Fórmula: C₁₂H₁₆N₆O₄

InChI: InChI=1S/C12H16N6O4/c1-2-14-11(21)8-6(19)7(20)12(22-8)18-4-17-5-9(13)15-3-16-10(5)18/h3-4,6-8,12,19-20H,2H2,1H3,(H,14,21)(H2,13,15,16)/t6-,7+,8-,12+/m0/s1

Clave InChI: InChIKey=JADDQZYHOWSFJD-FLNNQWSLSA-N

SMILES: O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](C(NCC)=O)[C@H]1O

Sinónimos:

• (2S,3R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,4-dihydroxytetrahydrofuran-2-carboxamide (non-preferred name)
• (2S,3S,4R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,4-dihydroxytetrahydrofuran-2-carboxamide (non-preferred name)
• (2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,4-dihydroxytetrahydrofuran-2-carboxamide (non-preferred name)
• 1-(6-Amino-9H-purin-9-yl)-1-deoxy-N-ethyl-beta-D-ribofuranuronamide
• 1-(6-Amino-9H-purin-9-yl)-1-deoxy-N-ethyl-β-<span class="text-smallcaps">D</span>-ribofuranuronamide
• 5'-N(Sup 6)-Ethylcarboxamidoadenosine
• 5'-N-Ethylcarboxamidoadenosine
• 5′-N⁶-Ethylcarboxamidoadenosine
• 744-96
• Adenosine 5′-ethylcarboxamide
• Adenosine-5'-(N-ethylcarboxamide)
• D-Neca
• beta-D-Ribofuranuronamide, 1-(6-amino-9H-purin-9-yl)-1-deoxy-N-ethyl-
• β-<span class="text-smallcaps">D</span>-Ribofuranuronamide, 1-(6-amino-9H-purin-9-yl)-1-deoxy-N-ethyl-
• β-D-Ribofuranuronamide, 1-(6-amino-9H-purin-9-yl)-1-deoxy-N-ethyl-

5'-N-Ethylcarboxamidoadenosine

CAS: 35920-39-9

5'-N-Ethylcarboxamidoadenosine

Pureza: ≥95%

Peso molecular: 308.29g/mol

Ref: 54-BUP06338

5''-Ethylcarboxamidoadenosine

CAS: 35920-39-9

Fórmula: C₁₂H₁₆N₆O₄

Peso molecular: 308.29

Ref: 7W-GN8868

5'-N-Ethylcarboxamidoadenosine

CAS: 35920-39-9

NECA, an adenosine receptor agonist, boosts brain extravasation of fluorescein and dextran without affecting the blood-brain barrier.

Fórmula: C₁₂H₁₆N₆O₄

Pureza: 98.95% - ≥95%

Forma y color: Powder

Peso molecular: 308.29

Ref: TM-T7340

5’-Ethylcarboxamido Adenosine

Producto controlado

CAS: 35920-39-9

Stability Hygroscopic
Applications A potent adenosine receptor agonist. Inhibits platelet aggregation and is centrally active in vivo.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Cusack and Hourani: Br. J. Pharmacol., 72, 433 (1981), Knapp, et al.: Pharmacol. Biochem. Behav., 68, 797 (2001)

Fórmula: C₁₂H₁₆N₆O₄

Forma y color: Neat

Peso molecular: 308.29

Ref: TR-E900980

5'-Ethylcarboxamidoadenosine

CAS: 35920-39-9

5'-Ethylcarboxamidoadenosine (5-ECA) is an adenosine receptor antagonist that is used as a radioligand to study the binding of adenosine and other nucleotides to their receptors. 5-ECA binds to the A3 receptor, which is a member of the G protein-coupled receptor family. This compound also inhibits platelet aggregation and has been shown to have anti-inflammatory effects in mice with colon cancer. 5-ECA was found to inhibit tumor growth in a mouse model system by suppressing IL-2 production and reducing levels of PGE2, an effect that may be due to inhibition of cyclase activity. 5-ECA can be used in vitro for studies on pluripotent cells because it does not affect their ability to differentiate.

Fórmula: C₁₂H₁₆N₆O₄

Pureza: Min. 95%

Forma y color: White Powder

Peso molecular: 308.29 g/mol

Ref: 3D-NE06155

5-Ethylcarboxamido Adenosine

CAS: 35920-39-9

Fórmula: C₁₂H₁₆N₆O₄

Peso molecular: 308.3

Ref: ST-EA-CP-A88069