CAS 367514-87-2

Lurasidona

Descripción:

Lurasidona es un medicamento antipsicótico atípico utilizado principalmente en el tratamiento de la esquizofrenia y el trastorno bipolar. Funciona como un antagonista del receptor de dopamina D2 y un antagonista del receptor de serotonina 5-HT2A, lo que contribuye a sus efectos terapéuticos. La fórmula química de Lurasidona es C24H25ClN2O2S, y presenta una estructura de tienobenzodiazepina. Lurasidona es conocido por su perfil de efectos secundarios relativamente favorable en comparación con otros antipsicóticos, particularmente en términos de efectos secundarios metabólicos. Se administra típicamente por vía oral y tiene una biodisponibilidad moderada, con su farmacocinética influenciada por la ingesta de alimentos. El fármaco se metaboliza principalmente por la enzima hepática CYP3A4, que puede verse afectada por otros medicamentos que inducen o inhiben esta enzima. Los efectos secundarios comunes pueden incluir sedación, akatisia y trastornos gastrointestinales. En general, Lurasidona representa un avance significativo en el manejo de los trastornos psicóticos, ofreciendo un equilibrio entre eficacia y tolerabilidad.

Fórmula: C₂₈H₃₆N₄O₂S

InChI: InChI=1/C28H36N4O2S/c33-27-24-18-9-10-19(15-18)25(24)28(34)32(27)17-21-6-2-1-5-20(21)16-30-11-13-31(14-12-30)26-22-7-3-4-8-23(22)35-29-26/h3-4,7-8,18-21,24-25H,1-2,5-6,9-17H2/t18-,19+,20-,21-,24+,25-/m0/s1

Clave InChI: InChIKey=PQXKDMSYBGKCJA-CVTJIBDQSA-N

SMILES: O=C1[C@]2([C@]([C@]3(C[C@@]2(CC3)[H])[H])(C(=O)N1C[C@H]4[C@H](CN5CCN(CC5)C=6C=7C(SN6)=CC=CC7)CCCC4)[H])[H]

Sinónimos:

• (3aR,4S,7R,7aS)-2-((1R,2R)-2-(4-(1,2-Benzothiazol-3-yl)piperazin-1-ylmethyl)cyclohexylmethyl)hexahydro-4,7-methano-2H-isoindole-1,3-dione
• (3aR,4S,7R,7aS)-2-[[(1R,2R)-2-[[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]methyl]cyclohexyl]methyl]hexahydro-4,7-methano-1H-isoindole-1,3(2H)-dione
• (3aR,4S,7R,7aS)-2-{[(1R,2R)-2-{[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]methyl}cyclohexyl]methyl}hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione
• 2-[[(1R,2R)-2-[[4-(1,2-Benzoisothiazol-3-yl)-1-piperazinyl]methyl]cyclohexyl]methyl]hexahydro-(3aS,4R,7S,7aR)-4,7-methano-1H-isoindole-1,3(2H)-dione
• 4,7-Methano-1H-isoindole-1,3(2H)-dione, 2-[[(1R,2R)-2-[[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]methyl]cyclohexyl]methyl]hexahydro-, (3aR,4S,7R,7aS)-
• Lurasidone
• 4-{[(1R,2R)-2-{[4-(2$l^{4}-thia-6-azatricyclo[5.4.0.0^{2,6}]undeca-1(11),2,4,7,9-pentaen-5-yl)piperazin-1-yl]Methyl}cyclohexyl]Methyl}-4-azatricyclo[5.2.1.0^{2,6}]deca-1(9),2(6),7-triene-3,5-dione
• Lurasidone Base
• Lurasidone, >=98%
• Lurasidone (SM13496)
• urasidone

Lurasidone

CAS: 367514-87-2

Fórmula: C₂₈H₃₆N₄O₂S

Pureza: >98.0%(HPLC)(N)

Forma y color: White to Orange to Green powder to crystaline

Peso molecular: 492.68

Ref: 3B-L0280

(3aR,4S,7R,7aS)-2-((1R,2R)-2-(4-(1,2-Benzothiazol-3-yl)piperazin-1-ylmethyl)cyclohexylmethyl)hexahydro-4,7-methano-2H-isoindole-1,3-dione

CAS: 367514-87-2

Fórmula: C₂₈H₃₆N₄O₂S

Pureza: 99%

Forma y color: Solid

Peso molecular: 492.6760

Ref: IN-DA0037AT

Lurasidone

CAS: 367514-87-2

Lurasidone

Pureza: 99%

Peso molecular: 492.68g/mol

Ref: 54-OR1028250

Lurasidone

CAS: 367514-87-2

Lurasidone

Pureza: ≥98%

Peso molecular: 492.68g/mol

Ref: 54-BUP06576

Lurasidone

CAS: 367514-87-2

Lurasidone (SM-13496) is an antagonist of both dopamine D2 and 5-HT7(IC50=1.68 and 0.495 nM, respectively).It also a partial agonist of 5-HT1A receptor(IC50 : 6

Fórmula: C₂₈H₃₆N₄O₂S

Pureza: 99.78% - 99.91%

Forma y color: Solid

Peso molecular: 492.68

Ref: TM-T21337

Lurasidone

Producto controlado

CAS: 367514-87-2

Applications Lurasidone (cas# 367514-87-2) is a useful research chemical.

Fórmula: C₂₈H₃₆N₄O₂S

Forma y color: Neat

Peso molecular: 492.68

Ref: TR-L474958

Lurasidone

Producto controlado

CAS: 367514-87-2

Lurasidone is an atypical antipsychotic medication, which is a synthetic compound developed through pharmaceutical chemical synthesis. It functions primarily as a dopamine D2 and serotonin 5-HT2A receptor antagonist, while also exhibiting partial agonism at certain serotonin receptors and antagonism at other neurotransmitter sites such as alpha-2 adrenergic receptors.Lurasidone is widely utilized in the medical field for the treatment of psychiatric disorders, notably schizophrenia and bipolar depression. Its multifaceted receptor activity profile helps in modulating neurotransmission imbalances associated with these conditions. By targeting specific neural pathways, lurasidone can effectively alleviate symptoms of psychosis, improve mood stability, and enhance overall cognitive function in patients. Researchers and clinicians value lurasidone for its efficacy in symptom management alongside a favorable side effect profile compared to older antipsychotics. Its pharmacological properties make it an important tool in advancing therapeutic approaches for complex psychiatric disorders.

Fórmula: C₂₈H₃₆N₄O₂S

Pureza: Min. 95%

Peso molecular: 492.68 g/mol

Ref: 3D-SPA51487